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Table 1 Summary of molecular markers of artemisinin and lumefantrine “resistance”

From: Making data map-worthy—enhancing routine malaria data to support surveillance and mapping of Plasmodium falciparum anti-malarial resistance in a pre-elimination sub-Saharan African setting: a molecular and spatiotemporal epidemiology study

 

Artemisinin

Lumefantrine

Marker name

k13

Pf mdr186

Pf crtK76T

Samples assayed (n)

2385

2812

2122

Wild type

2385 (100%)

2803 (99.7%)

2121 (99.9%)

Mutant

0(0%)

9 (0.3%)

0 (0%)

Mixed

0(0%)

0 (0%)

1 (0.1%)

  1. Prevalence of k13, mdr186 and crt76 mutations in individual patients with P. falciparum infections, Nkomazi Sub-District, Mpumalanga (March 2018–Feb 2020). Markers showing sensitive parasites include the wild type-k13, mutant-mdr186, and mutant/mixed crtK76T and potentially reduced susceptibility (or tolerant) markers with wild type-mdr186 and crtK76T