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Table 2 Effect of PMCA4 inhibition of ATA on the body weight changes and the red blood cells concentrations

From: Treatment with specific and pan-plasma membrane calcium ATPase (PMCA) inhibitors reduces malaria parasite growth in vitro and in vivo

Dosage

Day post infection

Monitoring indicators

Body weight

RBC

Weight (g)

Loss (%)

Count

Concentrations

Loss (%)

Sulfadoxine

25 mg/kg BW

1

20.75 (± .50)

0

89 (± 12.25)

4.5E+09 (± 6.1E+08)

0

9

21.25 (± 1.71)

2.41

78 (± 14.31)

3.9E+09 (± 7.2E+08)

− 12.36

14

21.75 (± 1.26)

4.82

101.5 (± 19.28)

5.1E+09 (± 9.6E+08)

14.04

Untreated

1

20.2 (± 1.48)

0

73.4 (± 10.31)

3.7E + 09 (± 5.2E+08)

0

9

21.2 (± .84)

4.95

45 (± 12.23)

2.3E+09 (± 6.1E+08)

− 38.69

14

18.4 (± .55)

− 8.91

32 (± 9.08)

1.6E+09 (± 4.5E+08)

− 56.40

ATA

30 mg/kg BW

1

17.00 (± 1.83)

0

69.7 (± 11.67)

3.5E+09 (± 5.8E+08)

0

9

16.57 (± .53)

− 2.52

61 (± 13.60)

3.1E+09 (± 6.8E+08)

− 12.50

14

16.17 (± .98)

− 4.90

36.3 (± 17.04)

1.8E+09 (± 8.5E+08)

− 47.95