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Table 2 Stratum-specific odds ratios of effect modifiers to the association of gravidity as a multi-level variable and placental malaria, among Ghanaian mothers aged 14–49, estimated by logistic regression fitted with interaction parameters after adjustmenta,b for confounders

From: Assessing the relationship between gravidity and placental malaria among pregnant women in a high transmission area in Ghana

Variable Category Gravidity group % PM (pm/N) Stratum specific OR (95% CI) P-value (LRT)
Stratified by area (N = 1823) Urban Multigravidae 29.5% (59/200) 1a 0.07
Secundigravidae 35.9% (33/92) 1.04 (0.60–1.81)a
Primigravidae 57.7% (52/90) 2.09 (1.17–3.71)a
Rural Multigravidae 25.8% (240/930) 1a
Secundigravidae 47.8% (119/249) 1.87 (1.34–2.62)a
Primigravidae 68.7% (180/262) 3.79 (3.61–5.51)a
Stratified by wealth index (N = 1823) Higher Multigravidae 23.1% (98/424) 1b 0.008
Secundigravidae 32.9% (51/155) 1.21 (0.79–1.86)b
Primigravidae 52.0% (78/150) 2.14 (1.38–3.35)b
Lower Multigravidae 28.5% (201/706) 1b
Secundigravidae 54.3% (101/186) 2.05 (1.41–2.98)b
Primigravidae 76.2% (154/202) 4.73 (3.08–7.25)b
Stratified by ITN use (N = 1782) Don’t use Multigravidae 23.9% (137/573) 1a 0.10
Secundigravidae 43.3% (62/143) 1.83 (1.20–2.79)a
Primigravidae 70.0% (100/145) 4.22 (2.68–6.67)a
Use Multigravidae 29.6% (158/532) 1a
Secundigravidae 45.6% (87/191) 1.39 (0.95–2.04)a
Primigravidae 62.6% (124/198) 2.36 (1.54–3.60)a
Doses of Fansidar (IPTp) (N = 1820) 0 Multigravidae 16.1% (10/62) 1 0.12
Secundigravidae 38.1% (8/21) 2.00 (0.63–6.27)
Primigravidae 69.2% (9/13) 7.13 (1.76–28.81)
1 Multigravidae 26.6% (37/139) 1
Secundigravidae 38.6% (17/44) 1.28 (0.61–2.69)
Primigravidae 78.4% (40/51) 5.50 (2.46–12.32)
2 Multigravidae 25.5% (72/282) 1
Secundigravidae 48.3% (42/87) 2.09 (1.22–3.56)
Primigravidae 71.0% (64/90) 4.86 (2.71–8.73)
3 Multigravidae 27.8% (179/645) 1
Secundigravidae 45.0% (85/189) 1.56 (1.07–2.28)
Primigravidae 60.4% (119/197) 2.38 (1.59–3.57)
  1. LRT Likelihood ratio test
  2. aAdjusted for age, wealth and relationship status
  3. bAdjusted for age relationship