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Table 3 Assessment of the diagnostic performance of the XN-31p using microscopy, RDT, and PCR as standards

From: Potential application of the haematology analyser XN-31 prototype for field malaria surveillance in Kenya

  Microscopy RDT PCR
Pos Neg Pos Neg Pos Neg
XN-31p (venous blood)
 Pos 16 2 18 0 18 0
 Neg 0 146 0 146 4 142
  Value 95% CI Value 95% CI Value 95% CI
 Sen 1.000 0.713–1.000 1.000 0.740–1.000 0.818 0.597–0.948
 Spe 0.986 0.952–0.998 1.000 0.963–1.000 1.000 0.962–1.000
 PPV 0.889 0.653–0.986 1.000 0.740–1.000 1.000 0.740–1.000
 NPV 1.000 0.963–1.000 1.000 0.963–1.000 0.973 0.931–0.992
XN-31p (capillary blood)
 Pos 16 2 18 0 18 0
 Neg 0 140 0 140 3 137
  Value 95% CI Value 95% CI Value 95% CI
 Sen 1.000 0.713–1.000 1.000 0.740–1.000 0.857 0.637–0.970
 Spe 0.986 0.950–0.998 1.000 0.961–1.000 1.000 0.960–1.000
 PPV 0.889 0.653–0.986 1.000 0.740–1.000 1.000 0.740–1.000
 NPV 1.000 0.961–1.000 1.000 0.961–1.000 0.979 0.939–0.996
  1. Pos positive, Neg negative, Sen sensitivity, Spe Specificity, PPV positive predictive value, NPV negative predictive value