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Table 3 Assessment of the diagnostic performance of the XN-31p using microscopy, RDT, and PCR as standards

From: Potential application of the haematology analyser XN-31 prototype for field malaria surveillance in Kenya

 

Microscopy

RDT

PCR

Pos

Neg

Pos

Neg

Pos

Neg

XN-31p (venous blood)

 Pos

16

2

18

0

18

0

 Neg

0

146

0

146

4

142

 

Value

95% CI

Value

95% CI

Value

95% CI

 Sen

1.000

0.713–1.000

1.000

0.740–1.000

0.818

0.597–0.948

 Spe

0.986

0.952–0.998

1.000

0.963–1.000

1.000

0.962–1.000

 PPV

0.889

0.653–0.986

1.000

0.740–1.000

1.000

0.740–1.000

 NPV

1.000

0.963–1.000

1.000

0.963–1.000

0.973

0.931–0.992

XN-31p (capillary blood)

 Pos

16

2

18

0

18

0

 Neg

0

140

0

140

3

137

 

Value

95% CI

Value

95% CI

Value

95% CI

 Sen

1.000

0.713–1.000

1.000

0.740–1.000

0.857

0.637–0.970

 Spe

0.986

0.950–0.998

1.000

0.961–1.000

1.000

0.960–1.000

 PPV

0.889

0.653–0.986

1.000

0.740–1.000

1.000

0.740–1.000

 NPV

1.000

0.961–1.000

1.000

0.961–1.000

0.979

0.939–0.996

  1. Pos positive, Neg negative, Sen sensitivity, Spe Specificity, PPV positive predictive value, NPV negative predictive value