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Table 3 The univariate and multivariate analyses of G6PD deficiency/G6PD normal, G6PD MahidolG487A/G6PD wildtype and haemoglobin levels adjusted by age, gender, parasite species, parasite density, PKLRR41Q, thalassaemia and haemoglobinopathies

From: Haematological profile of malaria patients with G6PD and PKLR variants (erythrocytic enzymopathies): a cross-sectional study in Thailand

Analysis type

Variable

Haemoglobin

Variable

Haemoglobin

B*

SE

Beta

p-value

B*

SE

Beta

p-value

Univariate

 

G6PD deficiency/G6PD normal

− 1.619

0.417

− 0.248

< 0.001

G6PD Mahidol/G6PD wildtype

− 1.415

0.495

− 0.182

0.005

 

Gender

− 0.773

0.66

− 0.074

0.243

Gender

− 0.773

0.66

− 0.074

0.243

 

Age

0.002

0.014

0.008

0.905

Age

0.002

0.014

0.008

0.905

 

Parasite count

5.492 × 106

0.000

0.106

0.095

Parasite count

5.462 × 106

0.000

0.106

0.095

 

Parasite species (P. falciparum/P. vivax)

− 0.485

0.264

− 0.117

0.067

Parasite species (P. falciparum/P. vivax)

− 0.485

0.264

− 0.117

0.067

 

PKLRR14Q

0.723

0.605

0.076

0.233

PKLRR14Q

0.723

0.605

0.076

0.233

 

Thalassaemia, haemoglobinopathies

− 0.467

0.258

− 0.114

0.072

Thalassaemia, haemoglobinopathies

− 0.467

0.258

− 0.114

0.072

Multivariate

 

G6PD deficiency/G6PD normal

− 1.895

0.447

− 0.270

< 0.001

G6PD Mahidol/G6PD wildtype

− 2.01

0.555

− 0.232

< 0.001

 

Gender

− 1.292

0.780

− 0.108

0.099

Gender

− 0.865

0.643

− 0.088

0.18

 

Age

0.002

0.014

0.011

0.871

Age

0.009

0.013

0.042

0.525

 

Parasite count

1.011 × 105

0.000

0.183

0.008

Parasite count

9.231 × 106

0.000

0.179

0.009

 

Parasite species (P. falciparum/P. vivax)

− 0.753

0.292

− 0.176

0.011

Parasite species (P. falciparum/P. vivax)

− 0.594

0.277

− 0.145

0.033

 

PKLRR14Q

0.862

0.616

0.089

0.164

PKLRR14Q

0.766

0.574

0.085

0.184

 

Thalassaemia, haemoglobinopathies

− 0.496

0.271

− 0.117

0.069

Thalassaemia, haemoglobinopathies

− 0.491

0.259

− 0.122

0.060

 

Constant

14.567

1.196

 

< 0.001

Constant

13.883

1.064

 

< 0.001

  1. Bold values indicate statistical significance at the p -value <0.05 level