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Table 3 The univariate and multivariate analyses of G6PD deficiency/G6PD normal, G6PD MahidolG487A/G6PD wildtype and haemoglobin levels adjusted by age, gender, parasite species, parasite density, PKLRR41Q, thalassaemia and haemoglobinopathies

From: Haematological profile of malaria patients with G6PD and PKLR variants (erythrocytic enzymopathies): a cross-sectional study in Thailand

Analysis type Variable Haemoglobin Variable Haemoglobin
B* SE Beta p-value B* SE Beta p-value
Univariate
  G6PD deficiency/G6PD normal − 1.619 0.417 − 0.248 < 0.001 G6PD Mahidol/G6PD wildtype − 1.415 0.495 − 0.182 0.005
  Gender − 0.773 0.66 − 0.074 0.243 Gender − 0.773 0.66 − 0.074 0.243
  Age 0.002 0.014 0.008 0.905 Age 0.002 0.014 0.008 0.905
  Parasite count 5.492 × 106 0.000 0.106 0.095 Parasite count 5.462 × 106 0.000 0.106 0.095
  Parasite species (P. falciparum/P. vivax) − 0.485 0.264 − 0.117 0.067 Parasite species (P. falciparum/P. vivax) − 0.485 0.264 − 0.117 0.067
  PKLRR14Q 0.723 0.605 0.076 0.233 PKLRR14Q 0.723 0.605 0.076 0.233
  Thalassaemia, haemoglobinopathies − 0.467 0.258 − 0.114 0.072 Thalassaemia, haemoglobinopathies − 0.467 0.258 − 0.114 0.072
Multivariate
  G6PD deficiency/G6PD normal − 1.895 0.447 − 0.270 < 0.001 G6PD Mahidol/G6PD wildtype − 2.01 0.555 − 0.232 < 0.001
  Gender − 1.292 0.780 − 0.108 0.099 Gender − 0.865 0.643 − 0.088 0.18
  Age 0.002 0.014 0.011 0.871 Age 0.009 0.013 0.042 0.525
  Parasite count 1.011 × 105 0.000 0.183 0.008 Parasite count 9.231 × 106 0.000 0.179 0.009
  Parasite species (P. falciparum/P. vivax) − 0.753 0.292 − 0.176 0.011 Parasite species (P. falciparum/P. vivax) − 0.594 0.277 − 0.145 0.033
  PKLRR14Q 0.862 0.616 0.089 0.164 PKLRR14Q 0.766 0.574 0.085 0.184
  Thalassaemia, haemoglobinopathies − 0.496 0.271 − 0.117 0.069 Thalassaemia, haemoglobinopathies − 0.491 0.259 − 0.122 0.060
  Constant 14.567 1.196   < 0.001 Constant 13.883 1.064   < 0.001
  1. Bold values indicate statistical significance at the p -value <0.05 level