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Table 2 Natural selection test and recombination analysis of Henan Province imported PfCSP and African native PfCSP C-termini

From: Genetic polymorphism of circumsporozoite protein of Plasmodium falciparum among Chinese migrant workers returning from Africa to Henan Province

Sample source

N

K

S

H

Hd ± SD

dN-dS

Tajima's D

Fu and Li's D

Fu and Li's F

Ra

Rb

Rm

Africa

   

 Congo

3

9.000

13

3

1.000 ± 0.272

0.076

 Cameroon

9

4.556

12

7

0.944 ± 0.070

0.038

− 0.84239

− 0.68964

− 0.81319

0.1006

15.9

2

 Kenya

18

5.843

18

13

0.928 ± 0.052

0.043

− 0.16823

− 0.13098

− 0.16414

0.1500

23.7

6

 Ghana

34

5.062

18

19

0.930 ± 0.027

0.042

− 0.20329

0.46554

0.29096

0.1025

16.2

6

 Gambia

44

5.966

18

21

0.951 ± 0.016

0.049

0.77207

1.34810

1.36435

0.1962

31.0

5

 Tanzania

60

6.382

21

29

0.966 ± 0.009

0.053

0.60634

0.80724

0.87500

0.2013

31.8

6

 Equatorial Guinea

96

4.906

21

33

0.948 ± 0.009

0.040

0.02365

− 0.40660

− 0.28991

0.1968

31.1

6

 Total

264

5.566

27

60

0.959 ± 0.004

0.046

0.19441

− 0.70174

− 0.38625

0.1683

26.6

7

Cases from Africa back to Henan province

  

 North Africa

3

3.333

5

2

0.667 ± 0.314

0.027

 East Africa

10

4.311

11

9

0.978 ± 0.054

0.035

− 0.28143

− 0.26257

− 0.30086

0.8861

140

2

 Central Africa

48

5.561

17

23

0.942 ± 0.017

0.046

0.56577

0.29295

0.45903

0.1108

17.5

6

 South Africa

57

6.056

18

30

0.963 ± 0.012

0.05

0.85180

1.37988

1.41794

0.3728

58.9

7

 West Africa

83

5.692

20

34

0.964 ± 0.008

0.047

0.55706

0.32378

0.49098

0.1399

22.1

6

 Total

201

5.719

21

60

0.964 ± 0.004

0.047

0.95250

1.00540

1.18403

0.1905

30.1

9

  1. N Sample size, SD standard deviation
  2. *P < 0.05; – The corresponding value cannot be calculated because there were few sequences (≤ 3)