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Fig. 4 | Malaria Journal

Fig. 4

From: Efficacy of three anti-malarial regimens for uncomplicated Plasmodium falciparum malaria in Cambodia, 2009–2011: a randomized controlled trial and brief review

Fig. 4

Comparing in vitro parasite drug resistance against common anti-malarials. Samples from 83 subject isolates with > 6400 parasites/µL were run in a classical isotopic P. falciparum in vitro drug resistance assay. In vitro resistance was calculated as the 50% inhibitory concentrations (IC50) based on serial dilutions of artesunate (AS), mefloquine (MQ), dihydroartemisin (DHA), piperaquine (PPQ), chloroquine (CQ) and quinine (QN). Resistance cut-offs established for the assays where known were used (MQ, CQ and QN). Resistance was compared between the three treatment groups (artesunate–mefloquine (A/M) in black circles; dihydroartemisin-piperaquine (DP) in blue squares, and atovaquone–proguanil (AP) in green triangles

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