Skip to main content

Table 3 Performance characteristics of two malaria rapid diagnostic tests, Aweil, South Sudan, 2019*

From: Evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria and prevalence of pfhrp2/3 deletions in Aweil, South Sudan

Characteristic test

Microscopy as gold standard

PCR as gold standard

N

Value

95% CI

N

Value

95% CI

Sensitivity

 pLDH

471

99.4

98.1–99.9

542

97.0

95.3–98.3

 HRP2

471

99.2

97.8–99.8

542

96.5

94.6–97.9

Specificity

 pLDH

329

55.0

49.5–60.5

258

65.1

59.0–70.9

 HRP2

329

61.7

56.2–67.0

258

72.9

67.0–78.2

PPV

 pLDH

616

76.0

72.4–79.3

616

85.4

82.3–88.1

 HRP2

593

78.8

75.2–82.0

593

88.2

85.3–90.7

NPV

 pLDH

184

98.4

95.3–99.7

184

91.3

86.3–94.9

 HRP2

207

98.1

95.1–99.5

207

90.8

86.0–94.4

  1. *PPV positive predictive value, NPV negative predictive value
  2. For sensitivity, N represents all true positives by microscopy or PCR; for specificity, N represents all true negatives by microscopy or PCR; for PPV, N represents all RDT test positives; and for NPV, N represents all RDT test negatives