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Table 7 Determinants of death within 28 days following enrolment

From: Key factors predicting suspected severe malaria case management and health outcomes: an operational study in the Democratic Republic of the Congo

Determinants

N

%

Adjusted OR

95% CI

p value

Age

     

 Children (0–2 years)

1255

57.6

Ref.

  

 Children (2–5 years)

923

42.4

0.44

0.29–0.65

< 0.001

Health Zone

     

 Ipamu

845

38.8

Ref.

  

 Kenge

749

34.4

0.66

0.35–1.24

0.19

 Kingandu

584

26.8

0.78

0.41–1.50

0.45

iCCM danger signs

     

 No/Others

415

19.1

Ref.

  

 Yes (iCCM general danger signs)

1614

74.1

1.57

0.94–2.61

0.08

 Unable to sit

149

6.8

0.14

0.02–1.13

0.07

RAS administration

     

 No

308

14.1

Ref.

  

 Yes

1870

85.9

1.50

0.86–2.60

0.15

Malaria test (RHF)

     

 Negative/Not done

999

45.9

Ref.

  

 Positive

1179

54.1

1.89

0.98–3.65

0.06

Anaemia on arrival at RHF

     

 No/mild anaemia/not done

1430

65.7

Ref.

  

 Anaemia (Hb < 5 g/dL)

748

34.3

2.13

1.22–3.69

0.008

Other comorbidities

     

 No

1501

68.9

Ref.

  

 Yes

677

31.1

1.13

0.67–1.91

0.64

Injectable antimalarial

     

 No/NA

970

44.5

Ref.

  

 Yes

1208

55.5

2.07

0.72–5.95

0.18

Oral antimalarial given at RHF

     

 No

1076

49.4

Ref.

  

 Yes

1102

50.6

0.13

0.07–0.26

< 0.001

Oral treatment given at discharge or prescribed

     

 No/NA

1499

68.8

Ref.

  

 Yes

679

31.2

0.53

0.25–1.13

0.10

Injectable antimalarial & ACT

     

 No

920

42.2

Ref.

  

 Yes

1258

57.8

0.26

0.09–0.79

0.018

  1. N = 2178. OR: Odds ratio; CHW: Community Health Worker; iCCM: integrated Community Case Management; PHC: Primary Health Care; RHF: Referral Health Facility; RAS: rectal artesunate; 95% CI: 95% confidence intervals; ACT: artemisinin-based combination therapy; Hb: Haemoglobin; NA: not applicable