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Table 4 The summarization of number of each genotypes for all patients

From: Association between CYP2D6 phenotype and recurrence of Plasmodium vivax infection in south Korean patients

Genotype

Frequency (%)

Genotype

Frequency (%)

*1/*1

11 (7.9)

*4/*10B

2 (1.4)

*1/*2

9 (6.5)

*5/*10B

9 (6.5)

*1/*2xN†

1 (0.7)

*5/*41

1 (0.7)

*1/*5

6 (4.3)

*5/*14B

1 (0.7)

*1/*10B

33 (23.7)

*10B/*10B

36 (25.9)

*1/*14B

1 (0.7)

*10B/*21B

1 (0.7)

*1/*21B

2 (1.4)

*10B/*41

2 (1.4)

*1/*41

3 (2.2)

*10B/*49

1 (0.7)

*1xN††/*5

1 (0.7)

*10B/*52

2 (1.4)

*2/*2

1 (0.7)

  

*2/*5

2 (1.4)

  

*2/*10B

10 (7.2)

  

*2/*14B

1 (0.7)

  

*2/*41

3 (2.2)

  
  1. †The phenotype of CYP2D6*2XN maintain UM even if the CYP gene duplicated or more
  2. ††The phenotype will be IM if CYP2D6*1XN gene is duplicated, and the phenotype changes to UM if multiplicated. According to the CYP2D6 frequency and CYP2D6 Allele Functionality Table (https://www.pharmgkb.org/page/cyp2d6RefMaterials), however, in East Asians, including Koreans, triplication or more copies are rarely reported, so it is generally assumed as duplication
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Malaria Journal

ISSN: 1475-2875

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