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Table 4 Case-specific parameters used by Dietz et al. [22]

From: Patient variability in the blood-stage dynamics of Plasmodium falciparum captured by clustering historical data

Notation

Definition

 

Calculation

m

Multiplication factor of the parasite

 

Maximum two-day multiplication factor by which the parasite density was multiplied by during the first wave (no units)

Pc

Critical effective density that determines the strength of the innate immune response

 

Critical parasite density at which the current multiplication factor was reduced by 50% (PRBC/µl)

Pm

Cumulative effective density that determines the strength of the adaptive immune response

 

Cumulative parasite density at which the current multiplication factor was reduced by 50% (PRBC/µl)

δ0

Delay of the onset of adaptive immunity

 

Estimated time of the first inflection points of the parasitaemia density (days)

  1. Notation, definitions and calculations of the case-specific parameters used by Dietz et al. [22]