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Fig. 2 | Malaria Journal

Fig. 2

From: Apicoplast ribosomal protein S10-V127M enhances artemisinin resistance of a Kelch13 transgenic Plasmodium falciparum

Fig. 2

Growth and development of the modified parasites. A Giemsa-stained parasites at 0, 24, 48, 72 and 96 h after initial invasion (hpi). Most parasites in each population of modified parasites were at the same stage of development as parental 3D7 parasites. B Fold increase in percentage parasitaemia over 2 cycles (96 h). The results are shown as means ± SD of 3 independent experiments. One-way ANOVA with Dunnett’s multiple comparisons test was performed. The growth of all transgenic parasites was not significantly different from 3D7 (95% CI). KMT = k13C580Y mutation, FMT = fdD193Y mutation, AMT = arps10V127M mutation

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