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Table 4 Tribe-wise phenotype distribution and allele frequency of HbS and α-thalassaemia among the unrelated 13 PVTGs of Odisha

From: A community based study on haemoglobinopathies and G6PD deficiency among particularly vulnerable tribal groups in hard-to-reach malaria endemic areas of Odisha, India: implications on malaria control

PVTG Tribe

AA

AS

SS

HbS

χ2

αα/αα

αα/–α

–α/–α

Hbα

χ2

Juang

64

2

0

0.015

0.0156

ND

ND

ND

  

Kutia Kondho

96

1

0

0.005

0.0026

ND

ND

ND

  

Paudi Bhuyan

202

6

1

0.019

11.57*

205

6

0

0.0142

0.0439

Dongoria Kondho

115

2

0

0.009

0.008

115

2

0

0.0085

0.0087

Langia Saora

117

10

0

0.039

0.213

120

7

0

0.0276

0.102

Didayi

67

6

0

0.041

0.134

70

3

0

0.0205

0.0321

Saora

139

13

0

0.042

0.303

146

5

1

0.023

10.989*

  1. AA normal individual; AS sickle cell heterozygote; SS sickle cell homozygote; HbS sickle cell allele; χ2 chi square value; αα/αα normal α gene; αα/–α α gene single gene deletion; -α/–α α double gene deletion; Hbα allele frequency of α gene deletion; ND not detected
  2. *Statistically significant (p < 0.05)