Naturally acquired antibodies from Beninese infants promote Plasmodium falciparum merozoite-phagocytosis by human blood leukocytes: implications for control of asymptomatic malaria infections

Table 3 Association between OP and total IgG to merozoite P. falciparum antigens

Opsonic phagocytosis	Coef.	95% CI	P value
Model 1: OP THP-1
AMA1	1.76	0.39;3.14	0.012	Number of observations = 87
MSP1	0.6	−1.34;2.54	0.544	Adj R² = 0.28
MSP3	16.56	−4.63;37.76	0.126
MSP2-3D7	−3	−6.99;0.98	0.140
MSP2-FC27	1.04	−3.47;5.54	0.652
GLURP-R0	−20.80	−50.45;8.84	0.169
GLURP-R2	12.24	1.35;23.12	0.028
Model 2: OP Neutrophils
AMA1	2.3	0.06;4.54	0.044	Number of observations = 87
MSP1	0.67	−2.49;3.84	0.677	Adj R² = 0.21
MSP3	23.89	−8.71;34.45	0.176
MSP2-3D7	−2.27	−6.27;1.99	0.493
MSP2-FC27	1.60	−5.59;3.80	0.669
GLURP-R0	17.65	−57.45;2.74	0.474
GLURP-R2	5.09	1.67;23.62	0.574

This table presents the generalized linear model obtained through the control variables bednet use, sex, and HbS. Total IgG to merozoite P. falciparum antigens were quantified at 18 months of age
In bold: significant P value at the 0.05 threshold

ISSN: 1475-2875