Table 5 Association between OP and IgG3 to merozoite P. falciparum antigens
Opsonic phagocytosis | Coef. | 95% CI | P value | |
|---|---|---|---|---|
Model 1: OP THP-1 | ||||
IgG3_AMA1 | Number of observations = 87 | |||
High | 7.93 | −0.38;16.24 | 0.061 | Adj R2 = 0.24 |
Low (reference) | ||||
IgG3_MSP1 | ||||
High | −2.68 | −9.69; 4.33 | 0.454 | |
Low (reference) | ||||
IgG3_MSP3 | ||||
High | −0.97 | −7.85;5.90 | 0.781 | |
Low (reference) | ||||
IgG3_MSP2-3D7 | ||||
High | 9.54 | −1.69;20.76 | 0.096 | |
Low (reference) | ||||
IgG3_MSP2-FC27 | ||||
High | 1.94 | −9.63;13.53 | 0.742 | |
Low (reference) | ||||
IgG3_GLURP-R0 | ||||
High | 1.14 | −5.74;8.04 | 0.744 | |
Low (reference) | ||||
IgG3_GLURP-R2 | ||||
High | 1.63 | −4.71;7.99 | 0.613 | |
Low (reference) | ||||
Model 2: OP Neutrophils | ||||
IgG3_AMA1 | Number of observations = 87 | |||
High | 20.4 | 7.64;33.15 | 0.002 | Adj R2 = 0.30 |
Low (reference) | ||||
IgG3_MSP1 | ||||
High | −6.12 | −16.88;4.63 | 0.265 | |
Low (reference) | ||||
IgG3_MSP3 | ||||
High | −0.74 | −11.29;9.80 | 0.890 | |
Low (reference) | ||||
IgG3_MSP2-3D7 | ||||
High | 7 | −10.24;24.25 | 0.426 | |
Low (reference) | ||||
IgG3_MSP2-FC27 | ||||
High | 0.72 | −17.04;18.05 | 0.936 | |
Low (reference) | ||||
IgG3_GLURP-R0 | ||||
High | −5.34 | −15.92;5.23 | 0.322 | |
Low (reference) | ||||
IgG3_GLURP-R2 | ||||
High | 5.51 | −4.23;15.26 | 0.268 | |
Low (reference) | ||||