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Table 6 IgG G3m phenotype distribution (A) and association between OP and IgG G3m phenotypes (B) 

From: Naturally acquired antibodies from Beninese infants promote Plasmodium falciparum merozoite-phagocytosis by human blood leukocytes: implications for control of asymptomatic malaria infections

A IgG G3m phenotypes

Number (n, %)

G3m5,10,11,13,14

35 (34.6)

G3m5,6,10,11,13,14,24

28 (27.7)

G3m5,6,10,11,13,14

12 (11.9)

G3m5,10,11,13,14,15

3 (3)

G3m5,6,11,24

6 (6)

G3m5,6,10,11,14

6 (6)

G3m5,6,10,11,13,14,15

3 (3)

G3m5,6,10,11,13,15,24

8 (7.9)

B Opsonic phagocytosis

Coef.

95% CI

P value

 

Model 1: OP neutrophils

   

Number of observations = 92

G3m5,10,11,13,14 (reference)

   

Adj R2 = 0.19

G3m5,6,10,11,13,14,24

13.46

2.37;24.54

0.017

 

G3m5,6,10,11,13,14

−4.31

−18.59;9.96

0.554

 

G3m5,10,11,13,14,15

6.86

−17.50;31.22

0.581

 

G3m5,6,11,24

2.08

−15.83;19.99

0.820

 

G3m5,6,10,11,14

7.82

−13.94;29.58

0.481

 

G3m5,6,10,11,13,14,15

29.27

−0.47;59.01

0.050

 

G3m5,6,10,11,13,15,24

−2.41

−17.58;12.75

0.755

 

Model 2: OP THP-1

   

Number of observations = 92

G3m5,10,11,13,14 (reference)

   

Adj R2 = 0.24

G3m5,6,10,11,13,14,24

7.46

0.31;14.61

0.041

 

G3m5,6,10,11,13,14

−6.00

−15.2;3.2

0.201

 

G3m5,10,11,13,14,15

−0.71

−16.41;14.99

0.929

 

G3m5,6,11,24

1.81

−9.73;13.36

0.759

 

G3m5,6,10,11,14

2.47

−11.56;16.49

0.730

 

G3m5,6,10,11,13,14,15

7.93

−11.24;27.10

0.417

 

G3m5,6,10,11,13,15,24

−2.92

−12.70;6.85

0.558

 
  1. This table presents the Generalized linear model obtained through the control variables bednet use, sex, birthweight and HbS. The reference group was G3m5,10,11,13,14
  2. In bold: significant P value at the 0.05 threshold