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Fig. 5 | Malaria Journal

Fig. 5

From: Gene Coverage Count and Classification (GC3): a locus sequence coverage assessment tool using short-read whole genome sequencing data, and its application to identify and classify histidine-rich protein 2 and 3 deletions in Plasmodium falciparum

Fig. 5

Median of standardized coverage between longitudinal subgroups. Median of standardized coverage [SUM (Coverage/Subtelomeric Mean Coverage)/ Total Samples] in hrp2 and hrp3 grouped by year of sample collection (Year). Countries include A. Cambodian hrp2 and hrp3 positions (n = 127), B. Malawi hrp2 and hrp3 positions (n = 150), C. Mali hrp2 and hrp3 positions (n = 90). Tan shading marks intron positions of target gene, whereas unshaded areas are exon positions (hrp2—> exon 1: 1,375,299–1,385,231; intron: 1,375,230–1,375,085; exon 2: 1,375,084–1,374,236; hrp3—> exon 1: 2,841,703–2,841,635; intron: 2,841,634–2,841,486; exon 2: 2,841,485–2,840,727). Analysis and figures were generated using R v4.1.1

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Malaria Journal

ISSN: 1475-2875

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