Compound | 24Â h | 48Â h | 72Â h | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
0.2 µM | 1.0 µM | 5.0 µM | 25.0 µM | 0.2 µM | 1.0 µM | 5.0 µM | 25.0 µM | 0.2 µM | 1.0 µM | 5.0 µM | 25.0 µM | |
phen | 1.06 ± 0.06 | 1.08 ± 0.09 | 0.91 ± 0.05 | 0.80 ± 0.04 | 1.78 ± 0.78 | 1.31 ± 0.21 | 1.40 ± 0.13 | 1.32 ± 0.31 | 1.35 ± 0.71 | 1.17 ± 0.44 | 1.08 ± 0.51 | 1.21 ± 1.25 |
1 | 1.04 ± 0.03 | 0.86 ± 0.04 | 0.59 ± 0.02 | 0.04 ± 0.03 | 0.32 ± 0.02 | 0.33 ± 0.05 | 0.72 ± 0.12 | 0.52 ± 0.26 | 1.09 ± 0.07 | 1.33 ± 0.41 | 1.69 ± 0.22 | − 1.66 ± 0.63 |
2 | 1.07 ± 0.05 | 1.10 ± 0.09 | 1.00 ± 0.02 | 1.04 ± 0.06 | − 0.54 ± 0.19 | − 0.44 ± 0.25 | − 0.07 ± 0.27 | − 0.97 ± 1.12 | 0.00 ± 0.03 | 0.34 ± 0.04 | 0.16 ± 0.04 | − 0.72 ± 0.02 |
3 | 0.04 ± 0.33 | − 0.64 ± 0.33 | − 1.32 ± 0.57 | − 7.33 ± 0.59 | 0.52 ± 0.60 | 0.66 ± 0.50 | 2.53 ± 0.85 | 3.39 ± 0.66 | − 0.24 ± 0.52 | − 0.79 ± 0.09 | 8.43 ± 0.60 | − 0.38 ± 0.32 |
4 | − 0.27 ± 0.19 | 0.44 ± 0.25 | − 0.41 ± 0.15 | − 2.29 ± 0.66 | − 1.53 ± 0.39 | − 0.42 ± 0.38 | 0.43 ± 0.09 | 0.39 ± 0.36 | − 0.03 ± 0.11 | 0.45 ± 0.32 | 0.33 ± 0.01 | 0.13 ± 0.05 |
Positive control | 24Â h | 48Â h | 72Â h | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
8 µM | 40 µM | 200 µM | 1000 µM | 8 µM | 40 µM | 200 µM | 1000 µM | 8 µM | 40 µM | 200 µM | 1000 µM | |
H2O2 | 1.10 ± 0.04 | 1.16 ± 0.13 | 1.08 ± 0.18 | 1.15 ± 0.22 | 1.78 ± 0.16 | 1.54 ± 0.28 | 1.41 ± 0.16 | 1.68 ± 0.28 | 1.82 ± 0.15 | 1.17 ± 0.36 | 2.06 ± 0.25 | 3.71 ± 0.14 |