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Table 2 Association between clinical presentation and malaria endemicity

From: Hospital-based surveillance of severe paediatric malaria in two malaria transmission ecological zones of Burkina Faso

    

Odd ratio (OR)

Clinical presentation

Total

Lower transmission area

Higher transmission area

Unadjusted OR (with 95% CI)

Adjusted OR (with 95% CI)

Coma

70

13 (2.6%)

57 (13.7%)

6.0 (3.2–11.2)**

6.5 (3.4–12.1) **

Convulsions

196

105 (20.8%)

91 (21.9%)

1.0 (0.8–1.5)

1.1 (0.8–1.5)

Prostration

385

162 (32.0%)

223 (53.7%)

2.5 (1.9–3.2) **

2.5 (1.9–3.3) **

Respiratory Distress

53

22 (4.3%)

31 (7.5%)

1.8 (1.0–3.1) **

1.8 (1.0–3.2) **

Abnormal bleeding

8

7 (1.4%)

1 (0.2%)

0.2 (0.02–1.4)

0.2 (0.1–1.3)

Circulatory collapse/shock

11

2 (0.4%)

9 (2.2%)

5.6 (1.2–26.0) **

5.9 (1.3–27.9) **

Haemoglobinuria

80

26 (5.1%)

54 (13.0%)

2.8 (1.7–4.5) **

2.7 (1.6–4.3) **

Incoercible vomiting

99

57 (11.2%)

42 (10.1%)

0.9 (0.6–1.4)

0.9 (0.6–1.3)

Lethargy

184

149 (29.4%)

35 (8.4%)

0.2 (0.1–0.3)

0.2 (0.1–0.3)

inability to drink /suck

37

19 (3.7%)

18 (4.3%)

1.2 (0.6–2.2)

1.1 (0.6–2.2)

Severe anaemia

448

252 (50.7%)

196 (47.5%)

0.9 (0.7–1.1)

0.9 (0.7–1.1)

Hypoglycaemia

43

17 (3.4%)

26 (6.4%)

1.9 (1.0–3.6) **

1.9 (1.0–3.6) **

  1. **statistically significant difference between LMT and HMT