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Table 3 Case fatality rates associated with the different clinical presentations

From: Hospital-based surveillance of severe paediatric malaria in two malaria transmission ecological zones of Burkina Faso

 

CFR (%, 95%CI)

 

Clinical presentation

Lower transmission area

Higher transmission area

Overall

Coma

2/13 (15.3%, 1.9–45.4%)

9/53 (16.9%, 8.1–29.8%))

11/66 (16.7%, 8.6–27.9%))

Convulsions

7/102 (6.9%, 2.8–13.6%))

7/86 (8.1%, 3.3–16.0%)

14/188 (7.4%, 4.1–12.2%)

Prostration

10/154 (6.5%, 3.1–11.6%)

18/213 (5.1–13.0%)

28/367 (7.6%, 5.1–10.8%)

Respiratory Distress

5/21 (23.8%, 8.2–47.2%)

8/29 (27.6%, 12.8–47.2%)

13/50 (26.0%, 14.6–40.3%)

Abnormal bleeding

Circulatory collapse/shock

0/2 (–)

2/9 (22.2%, 2.8–60.0%)

2/11 (18.2%, 2.3–51.8%)

Haemoglobinuria

1/23 (4.3%, 0.1–21.9%))

3/53 (5.7%, 1.2–15.7%)

4/76 (5.3%, 1.4–12.9%)

Incoercible vomiting

3/56 (5.4%, 1.1–14.9%)

1/42 (2.4%, 0.1–12.6%)

4/98 (4.1%, 1.1–10.1%)

Lethargy

5/144 (3.5%, 1.1–7.9%)

3/34 (8.8%, 1.8–23.7%)

8/178 (4.5%, 1.9–8.7%)

Inability to drink /suck

5/18 (27.8%, 9.7–53.5%)

2/18 (11.1%, 1.4–34.7%)

7/36 (19.4%, 8.2–36.0%)

Severe anaemia

7/243 (2.9%, 1.2–5.8%)

8/180 (4.4%, 1.9–8.6%)

15/423 (3.5%, 2.0–5.8%)

Hypoglycaemia

3/17 (17.6%, 3.8–43.4%)

7/23 (30.4%, 13.2–52.9%)

10/40 (25%, 12.7–41.2%)