Impact of insecticide resistance on malaria vector competence: a literature review

Suh, Pierre Fongho; Elanga-Ndille, Emmanuel; Tchouakui, Magellan; Sandeu, Maurice Marcel; Tagne, Darus; Wondji, Charles; Ndo, Cyrille

doi:10.1186/s12936-023-04444-2

Malaria Journal

Table 1 Summary of studies evaluating the impact of insecticide resistance on malaria vectors susceptibility to P. falciparum infection

From: Impact of insecticide resistance on malaria vector competence: a literature review

Mosquito species	Type of experiment performed	Type of infection	Infection outcome		References
Mosquito species	Type of experiment performed	Type of infection	Prevalence	Intensity	References
An. gambiae^a	kdr-resistant strain compared to susceptible strain	Natural	Higher sporozoite infection prevalence in resistant strain^s		[27]
An. funestus s.s^a	GSTe2-resistant genotypes compared to susceptible genotypes	Natural	No difference in oocysts infection prevalence ^ns Higher sporozoite infection prevalence in resistant strain^s		[28]
An. gambiae s.l.^a	ace-1-resistant strain compared to susceptible strain	Natural	Higher oocyst infection prevalence in resistant strain^s		[29]
An. gambiae s.l.^a	kdr-resistant strain compared to susceptible strain	Natural	No difference in oocysts infection prevalence ^ns		[29]
An. gambiae^a	kdr-resistant strain compared to susceptible strain	Experimental	Higher oocyst infection prevalence in resistant strain^s Higher sporozoite infection prevalence in resistant strain^s	Higher oocyst load in the resistant strain^s Higher sporozoite infection load in the resistant strain^s	[30]
An. coluzzii^a	kdr-resistant strain compared to susceptible strain	Experimental	Higher oocyst prevalence in the resistant strain^s Higher sporozoite infection prevalence in resistant strain^s	Higher oocysts load in the resistant strain^s Higher sporozoite load prevalence in the resistant strain^s	[30]
An. funestus s.s^a	GSTe2-resistant genotypes compared to susceptible genotypes	Experimental	Lower oocyst infection prevalence in homozygous resistant genotypes^s	Higher oocysts load in homozygous and heterozygous resistant genotypes^s	[31]
An. gambiae^b	ace-1-resistant strain compared to susceptible strain	Experimental	Higher oocyst prevalence infection in resistant strain^s No difference in sporozoite infection prevalence^ns	No difference in oocyst and sporozoite infection load^ns	[32]
An. gambiae^b	kdr-resistant strain compared to susceptible strain	Experimental	Higher oocyst infection prevalence in resistant strain^s Higher sporozoite infection prevalence in resistant strain^s	Lower oocyst and sporozoite infection load in resistant strain^s	[32]
An. gambiae^b	ace-1-resistant strain compared to susceptible strain		Higher oocyst infection prevalence in resistant strain^s		[33]
An. gambiae^b	kdr-resistant strain compared to susceptible strain	Experimental	Higher oocyst infection prevalence in resistant strain^s		[33]
An. gambiae^b	kdr-resistant strain compared to kdr-resistant strain exposed to insecticides		Lower oocyst infection prevalence in resistant strain^s	No difference in oocyst infection load^ns	[34]
An. gambiae^b	ace-1-resistant strain compared to ace-1-resistant strain exposed to insecticides	Experimental	Lower oocyst infection prevalence in resistant strain^s	Lower oocyst infection load in resistant strain^s	[34]
An. gambiae^a	kdr-resistant strain compared to kdr-resistant strain exposed to insecticide-treated nets	Experimental	Lower oocyst infection prevalence in resistant strain^s	Lower oocyst infection load in resistant strain^s	[35]

a: field strain; b: laboratory strain; ns: Non Significant; s: Significant; α: insecticide exposure to confirm resistance status probably post infection; β: insecticide exposure to confirm resistance status prior to infection

Back to article page

ISSN: 1475-2875

Contact us

Submission enquiries: journalsubmissions@springernature.com