Table 2 Distributions of SNPs/MNPs/INDELs of P. falciparum kelch 13 (PfK13), Pfcoronin, multidrug resistance protein 1(Pfmdr1), multidrug resistance protein 2 (Pfmdr2), dihydropteroate synthetase (Pfdhps), dihydrofolate reductase (Pfdhfr), multidrug resistance-associated protein 2 (Pfmrp2), and signal peptide peptidase (PfSPP) genes for D10 and D30 (RSA Positive) and P32 and P36 (RSA Negative) isolates and their frequencies
Sample ID | Â | D30 | D10 | P36 | P32 | SNPs/INDELs total |
|---|---|---|---|---|---|---|
Gene name | SNPs/INDELs | |||||
PfCoronin | S183G | 1 | Â | 1 | Â | 2 |
| Â | V424I | 1 | 1 | Â | Â | 2 |
PfK13 | K189T | Â | 1 | 1 | 1 | 3 |
| Â | K188* | 1 | Â | Â | Â | 1 |
Pfmdr1 | Y184F | Â | 1 | Â | 1 | 2 |
| Â | D650N | Â | 1 | Â | Â | 1 |
| Â | N86Y | 1 | Â | Â | Â | 1 |
| Â | N652D | Â | 1 | Â | Â | 1 |
Pfmdr2 | S208N | 1 | 1 | Â | 1 | 3 |
| Â | F423Y | 1 | 1 | Â | 1 | 3 |
| Â | N245S | Â | 1 | Â | Â | 1 |
| Â | I492V | Â | 1 | Â | 1 | 2 |
| Â | Del (ATT/ASN) | 1 | 1 | 1 | 1 | 4 |
Pfdhfr | S108N | 1 | 1 | 1 | 1 | 4 |
| Â | N51I | 1 | 1 | 1 | Â | 3 |
| Â | D212I | 1 | Â | Â | Â | 1 |
| Â | C59R | 1 | 1 | 1 | Â | 3 |
Pfdhps | I431M | Â | Â | 1 | Â | 1 |
| Â | A613S | Â | Â | 1 | 1 | 2 |
| Â | S436A | Â | 1 | 1 | 1 | 3 |
| Â | A581G | Â | Â | 1 | Â | 1 |
SPP | Insert (T) | Â | 1 | Â | Â | 1 |
Pfmrp2 | L199V | 1 | 1 | 1 | 1 | 4 |
| Â | D634N | 1 | Â | 1 | 1 | 3 |
| Â | D650N | 1 | Â | Â | Â | 1 |
| Â | N642D | 1 | Â | 1 | 1 | 3 |
| Â | D1951N | 1 | 1 | Â | Â | 2 |
| Â | K714I | 1 | Â | 1 | 1 | 3 |
| Â | L295V | Â | Â | Â | 1 | 1 |
| Â | L1531I | 1 | Â | 1 | 1 | 3 |
| Â | S1527T | 1 | 1 | 1 | 1 | 4 |
| Â | K1842I | Â | Â | Â | 1 | 1 |
| Â | S1371N | Â | Â | Â | 1 | 1 |
| Â | D631G | Â | 1 | 1 | 1 | 3 |