Test drugs (IC50 nM, 95% CI) | |||||||
---|---|---|---|---|---|---|---|
 | ART | AS | DHA | AM | LUM | AQ | RSA% |
3D7 | 4.58 (4.17–5.00) | 2.75 (2.66–2.85) | 4.08 (3.76–4.41) | 4.60 (4.38–4.82) | 8.52 (7.49–9.55) | 7.16 (6.40–7.93) | 0.0 |
D30 | 4.65 (3.19–6.11) | 6.17 (5.08–7.25) | 5.35 (3.76–6.93) | 7.23 (5.92–8.55) | 15.71 (13.43–17.98) | 11.8 (8.91–14.69) | 13.0 |
D10 | 10.81 (9.69–11.94) | 9.28 (8.22–10.35) | 11.78 (10.31–13.25) | 7.21 (6.33–8.10) | 10.28 (9.59–10.96) | 11.87 (10.83–12.91) | 19.0 |
P52 | 12.93 (11.22–14.65) | 6.64 (6.19–7.10) | 5.18 (4.16–6.20) | 5.95 (5–60-9.00) | 9.16 (8.79–9.53) | 11.4 (10.9–11.89) | 0.0 |
P32 | 6.43 (5.35–7.5) | 6.06 (5.37–6.74) | 4.55 (3.42–5.68) | 7.49 (6.03–8.95) | 16.43 (14.44–18.41) | 15.02 (12.41–17.63) | 0.0 |
S22 | 5.75 (4.38–7.12) | 6.33 (5.10–7.56) | 6.70 (5.93–7.46) | 6.71 (5.41–8.01) | 11.26 (10.46–12.06) | 21.78 (18.54–225.0) | 0.0 |
S19 | 5.09 (2.95–7.23) | 5.13 (3.5–6.77) | 3.57 (2.29–4.85) | 8.31 (6.11–10.50) | 9.73 (7.9–11.57) | 12.23 (8.9–15.55) | 0.0 |