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Table 5 Epidemiological profile of pregnant women with microscopic parasitaemia versus those with sub-microscopic infection at GA ≥ 36 weeks in the Mount Cameroon area

From: Sub-microscopic Plasmodium falciparum parasitaemia, dihydropteroate synthase (dhps) resistance mutations to sulfadoxine–pyrimethamine, transmission intensity and risk of malaria infection in pregnancy in Mount Cameroon Region

Variable

Category

Malaria infection status [% (n)]

Unadjusted odds ratio (95% CI)

Adjusted odds ratio (95% CI)

p-value

Microscopic

Sub-microscopic

Age group (years)

 < 21

50.0 (16)

50.0 (16)

2.10 (0.88–5.03)

1.26 (0.31–5.16)

0.752

21–25

31.4 (16)

68.6 (35)

0.96 (0.43–2.13)

1.34 (0.44–4.08)

0.603

 > 25

32.3 (20)

67.7 (42)

REF

REF

 

Season

Rainy

27.1 (26)

72.9 (70)

0.33 (0.16–0.67)

0.36 (0.14–0.94)

0.036

Dry

53.1 (26)

46.9 (23)

REF

REF

 

Study area

Semi-rural

56.1 (37)

43.9 (29)

5.02 (2.41–10.45)

7.09 (2.59–19.42)

 < 0.001

Semi-urban

19.0 (15)

81.0 (64)

REF

REF

 

Gravidity status

Primigravidae

46.3 (19)

53.7 (22)

1.73 (0.77–3.37)

1.13 (0.29–4.37)

0.859

Secundigravidae

29.3 (12)

70.7 (29)

0.83 (0.35–1.94)

0.67 (0.21–2.13)

0.502

Multigravidae

33.3 (21)

66.7 (42)

REF

REF

 

Dosage frequency of SP

 ≥ 3 doses

37.5 (21)

62.5 (35)

0.78 (0.34–1.79)

0.49 (0.17–1.41)

0.187

2 doses

28.0 (14)

72.0 (36)

0.50 (0.21–1.22)

0.29 (0.09–0.90)

0.032

 ≤ 1 dose

43.6 (17)

56.4 (22)

REF

REF

 

ITN usage

Yes

38.6 (32)

61.4 (51)

1.51 (0.64 – 3.56)

1.81 (0.58–5.66)

0.305

No

35.7 (10)

64.3 (18)

1.25 (0.38 – 4.08)

4.35 (0.99–19.06

0.052

No ITN

29.4 (10)

70.6 (24)

REF

REF

 

Fever history

Yes

44.4 (28)

55.6 (35)

1.93 (0.97–3.85)

2.60 (1.07–6.31)

0.035

No

29.3 (24)

70.7 (58)

REF

REF

 

DHPS mutation status

A437G only

23.8 (5)

76.2 (16)

0.84 (0.26–2.76)

1.12 (0.28–4.47)

0.875

A581G only

33.3 (16)

66.7 (32)

1.35 (0.56–3.23)

1.39 (0.48–4.00)

0.546

Double mutation

64.3 (18)

35.7 (10)

4.85 (1.78–13.19)

6.65 (1.85–23.96)

0.004

Negative for dhps mutation

27.1 (13)

72.9 (35)

REF

REF