From: A review of efficacy and safety of Ugandan anti-malarial plants with application of RITAM score
Parameters | Inclusion criteria | Exclusion criteria |
---|---|---|
Part of the plant studied (Leaves, Stembark, Roots, Fruits, Flowers) | Leaves, Fruits, Stembark, Seeds (In case of activities reported on different parts, the one with best activity is considered for scores) | Flowers and Roots |
Extraction solvent—Aqueous., Petroleum Ether, Dichloromethane, Ethanol, Methanol) | The one which gives the best activity | The one with less activity |
Location of the study plant part collection (Uganda, E. Africa, Africa) | In Uganda and from all other parts if the active compound is known | Outside Uganda and active anti-malarial compound is not known for the plant species |
RITAM SCORE [19] | ||
Test | Test Result Range | Score |
In vitro Antiplasmodial Test (µg/mL) | Not tested | 0 |
 < 2 | 10 | |
2.0 – 5.0 | 5 | |
5.1 – 10 | 3 | |
11 – 25 | 2 | |
26 – 50 | 1 | |
Activity confirmed in more than one strain of P. falciparum | 2 | |
In vivo Antiplasmodial Test in mice (% inhibition) | Not tested | 0 |
100 – 90 | 10 | |
 | 90 – 50 | 9 – 5 |
 | 50 – 10 | 5 – 1 |
 | 0 | -2 |