Table 3 Diagnostic accuracy of microscopy and RDT using qPCR as reference
Performance metric | Test | |
|---|---|---|
RDT | Microscopy | |
TP (qPCR = 438) | 244 | 172 |
FP (qPCR negative) | 11 | 10 |
TN (qPCR = 602) | 591 | 592 |
FN (qPCR positive) | 194 | 266 |
Sensitivity % (95% C.I.) | 55.7 (51.0–60.3) | 39.3 (34.8–43.9) |
Specificity % (95% C.I.) | 98.2 (96.8–99.0) | 98.3 (97.0–99.1) |
PPV % (95% C.I.) | 95.7 (92.4–97.6) | 94.5 (90.2–97.0) |
NPV % (95% C.I.) | 75.3 (72.2–78.2) | 69.0 (65.8–72.0) |
Accuracy % | 80.3 | 73.5 |
kappa value (95% C.I.) | 0.571 (0.523–0.620) | 0.409 (0.359–0.458) |