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Table 2 Distribution of children with acute uncomplicated malaria according to symptoms other than fever at presentation by treatment groups

From: Efficacy and safety of pyronaridine–artesunate versus artemether–lumefantrine in the treatment of acute uncomplicated malaria in children in South-West Nigeria: an open-labelled randomized controlled trial

Presenting complaint

Total population

Artemether–lumefantrine

Pyronaridine–artesunate

ρ-value

N = 172 (100)

N = 87 (100%)

N = 85 (100%)

Headaches

120 (69.8)

61 (70.1)

59 (69.4)

1.000

Chills and rigors

117 (68.0)

66 (75.9)

51 (60)

0.033

Loss of appetite

101 (58.7)

59 (67.8)

42 (49.4)

0.014

Vomiting

82 (47.7)

44 (50.6)

38 (44.7)

0.450

Abdominal pain

68 (39.5)

33 (37.9)

35 (41.7)

0.642

Nausea

54 (31.4)

30 (34.5)

24 (28.6)

0.417

Cough

45 (26.2)

21 (24.1)

24 (28.6)

0.603

Diarrhea

32 (18.6)

18 (20.7)

14 (16.5)

0.558

Irritability

33 (19.2)

13 (14.9)

20 (23.5)

0.178

Insomnia

17 (9.9)

10 (11.5)

7 (8.3)

0.611

Palpitations

10 (5.8)

5 (6.0)

5 (5.7)

1.000