Fig. 2

Distribution patterns of immediate ex vivo susceptibilities of Plasmodium falciparum clinical isolates to isoliensinine and standard anti-malarial drugs. Geometric mean IC_50s^IEV for the 10 clinical isolates were; CQ = 0.011 µM (95% CI 0.008–0.016), AMQ = 0.005 µM (95% CI 0.004–0.007), DHA = 0.005 µM (95% CI 0.003–0.010), ARS = 0.002 µM (95% CI 0.002–0.004), MQ = 0.016 µM (0.010–0.026), ARM = 0.005 µM (95% CI 0.003–0.007), PPQ = 0.046 µM (95% CI 0.030–0.070), ATQ = 0.003 µM (95% CI 0.001–0.005), ART = 0.010 µM (95% CI 0.007–0.014), LUM = 0.132 µM (95% CI 0.070–0.250), QN = 0.062 µM (95% CI 0.038–0.102), and isoliensinine = 1.433 µM (95% CI 0.917–2.242). Each point represents a single isolate. The horizontal lines between the distribution patterns represent median IC_50s for respective treatments