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  1. The most important factor for effective zooprophylaxis in reducing malaria transmission is a predominant population of a strongly zoophilic mosquito, Anopheles arabiensis. The feeding preference behaviour of Anop...

    Authors: Aneth Mahande, Franklin Mosha, Johnson Mahande and Eliningaya Kweka

    Citation: Malaria Journal 2007 6:100

    Content type: Research

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  2. Severe falciparum malaria in children was studied as part of the characterization of the Kassena-Nankana District Ghana for future malaria vaccine trials. Children aged 6–59 months with diagnosis suggestive of...

    Authors: Abraham R Oduro, Kwadwo A Koram, William Rogers, Frank Atuguba, Patrick Ansah, Thomas Anyorigiya, Akosua Ansah, Francis Anto, Nathan Mensah, Abraham Hodgson and Francis Nkrumah

    Citation: Malaria Journal 2007 6:96

    Content type: Research

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  3. The C-terminal region of merozoite surface protein-1 (MSP-1) is one of the leading candidates for vaccination against the erythrocytic stages of malaria. However, a major concern in the development of MSP-1 ba...

    Authors: Anitha Mamillapalli, Sujatha Sunil, Suraksha S Diwan, Surya K Sharma, Prajesh K Tyagi, Tridibes Adak, Hema Joshi and Pawan Malhotra

    Citation: Malaria Journal 2007 6:95

    Content type: Research

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  4. In 2003, artesunate-amodiaquine (AS+AQ) was introduced as the new first-line treatment for uncomplicated malaria in Burundi. After confirmed diagnosis, treatment was delivered at subsidized prices in public he...

    Authors: Sibylle Gerstl, Sandra Cohuet, Kodjo Edoh, Christopher Brasher, Alexandre Lesage, Jean-Paul Guthmann and Francesco Checchi

    Citation: Malaria Journal 2007 6:94

    Content type: Research

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  5. African highlands often suffer of devastating malaria epidemics, sometimes in conjunction with complex emergencies, making their control even more difficult. In 2000, Burundian highlands experienced a large ma...

    Authors: Natacha Protopopoff, Michel Van Herp, Peter Maes, Tony Reid, Dismas Baza, Umberto D'Alessandro, Wim Van Bortel and Marc Coosemans

    Citation: Malaria Journal 2007 6:93

    Content type: Case study

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  6. A combination of artesunate (AS) plus sulphadoxine/pyrimethamine (SP) as first-line and artemether-lumefantrine (AL) as second-line treatment are currently recommended against uncomplicated P. falciparum infectio...

    Authors: Ebtihal A Mukhtar, Nahla B Gadalla, Salah-Eldin G El-zaki, Izdihar Mukhtar, Fathi A Mansour, Ahmed Babiker and Badria B El-Sayed

    Citation: Malaria Journal 2007 6:92

    Content type: Research

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  7. Having reliable forecasts is critical now for producers, malaria-endemic countries and agencies in order to adapt production and procurement of the artemisinin-based combination treatments (ACTs), the new firs...

    Authors: Jean-Marie Kindermans, Daniel Vandenbergh, Ed Vreeke, Piero Olliaro and Jean-Pierre D'Altilia

    Citation: Malaria Journal 2007 6:91

    Content type: Research

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  8. The objective of this study was to investigate whether the infection of C57BL/6 mice by P. berghei ANKA, which causes severe malaria, was modulated by co-infection with Trypanosoma cruzi.

    Authors: Claudia M Egima, Silene F Macedo, Gisela RS Sasso, Charles Covarrubias, Mauro Cortez, Fernando Y Maeda, Fabio T Costa and Nobuko Yoshida

    Citation: Malaria Journal 2007 6:90

    Content type: Research

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  9. Intermittent preventive treatment with sulphadoxine-pyrimethamine (IPT-SP) is currently the recommended regimen for prevention of malaria in pregnancy in endemic areas. This study sets out to evaluate the effe...

    Authors: Catherine O Falade, Bidemi O Yusuf, Francis F Fadero, Olugbenga A Mokuolu, Davidson H Hamer and Lateef A Salako

    Citation: Malaria Journal 2007 6:88

    Content type: Research

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  10. Genetic linkage mapping identified a region of chromosome 2L in the Anopheles gambiae genome that exerts major control over natural infection by Plasmodium falciparum. This 2L Plasmodium-resistance interval was m...

    Authors: Michelle M Riehle, Kyriacos Markianos, Louis Lambrechts, Ai Xia, Igor Sharakhov, Jacob C Koella and Kenneth D Vernick

    Citation: Malaria Journal 2007 6:87

    Content type: Research

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  11. Asexual stage antibody responses following initial Plasmodium falciparum infections in previously healthy adults may inform vaccine development, yet these have not been as intensively studied as they have in popu...

    Authors: Damon P Eisen, Lina Wang, Helene Jouin, E Elsa H Murhandarwati, Casilda G Black, Odile Mercereau-Puijalon and Ross L Coppel

    Citation: Malaria Journal 2007 6:86

    Content type: Research

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  12. The anti-malarial chloroquine can modulate the outcome of infection during the Plasmodium sporogonic development, interfering with Plasmodium gene expression and subsequently, with transmission. The present study...

    Authors: Henrique Silveira, Susana Ramos, Patrícia Abrantes, Luís Filipe Lopes, Virgílio E do Rosario and Mitchell S Abrahamsen

    Citation: Malaria Journal 2007 6:84

    Content type: Research

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  13. Prompt access to effective treatment is central in the fight against malaria. However, a variety of interlinked factors at household and health system level influence access to timely and appropriate treatment...

    Authors: Manuel W Hetzel, Nelly Iteba, Ahmed Makemba, Christopher Mshana, Christian Lengeler, Brigit Obrist, Alexander Schulze, Rose Nathan, Angel Dillip, Sandra Alba, Iddy Mayumana, Rashid A Khatib, Joseph D Njau and Hassan Mshinda

    Citation: Malaria Journal 2007 6:83

    Content type: Case study

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  14. Data suggest that antibody responses to malaria parasites merozoite antigens are generally short-lived and this has implications for serological studies and malaria vaccine designs. However, precise data on th...

    Authors: Samson M Kinyanjui, David J Conway, David E Lanar and Kevin Marsh

    Citation: Malaria Journal 2007 6:82

    Content type: Research

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  15. On the borders of Thailand, Plasmodium falciparum has become resistant to nearly all available drugs, and there is an urgent need to find new antimalarial drugs or drug combinations. Ferroquine (SSR97193) is a ne...

    Authors: Marion Barends, Anchalee Jaidee, Nopparat Khaohirun, Pratap Singhasivanon and François Nosten

    Citation: Malaria Journal 2007 6:81

    Content type: Case study

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  16. In view of the high level of chloroquine resistance in many countries, WHO has recommended the use of combination therapy with artemisinin derivatives in the treatment of uncomplicated malaria due to Plasmodium f...

    Authors: Babacar Faye, Jean-Louis Ndiaye, Daouda Ndiaye, Yemou Dieng, Oumar Faye and Oumar Gaye

    Citation: Malaria Journal 2007 6:80

    Content type: Research

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  17. Malaria microscopy, while the gold standard for malaria diagnosis, has limitations. Efficacy estimates in drug and vaccine malaria trials are very sensitive to small errors in microscopy endpoints. This fact l...

    Authors: Colin Ohrt, Peter Obare, Ampon Nanakorn, Christine Adhiambo, Ken Awuondo, Wendy Prudhomme O'Meara, Shon Remich, Kurt Martin, Earnest Cook, Jean-Paul Chretien, Carmen Lucas, Joseph Osoga, Peter McEvoy, Martin Lucas Owaga, James Sande Odera and Bernhards Ogutu

    Citation: Malaria Journal 2007 6:79

    Content type: Case study

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  18. The var multigene family encodes PfEMP1, which are expressed on the surface of infected erythrocytes and bind to various host endothelial receptors. Antigenic variation of PfEMP1 plays a key role in malaria patho...

    Authors: Madeleine Dahlbäck, Thomas Lavstsen, Ali Salanti, Lars Hviid, David E Arnot, Thor G Theander and Morten A Nielsen

    Citation: Malaria Journal 2007 6:78

    Content type: Research

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  19. Investigation of host responses to blood stages of Plasmodium spp, and the immunopathology associated with this phase of the life cycle are often performed on mice infected directly with infected red blood cel...

    Authors: Luis Fonseca, Elsa Seixas, Geoffrey Butcher and Jean Langhorne

    Citation: Malaria Journal 2007 6:77

    Content type: Research

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  20. Mosquito larval control may prove to be an effective tool for incorporating into integrated vector management (IVM) strategies for reducing malaria transmission. Here the efficacy of microbial larvicides against

    Authors: Silas Majambere, Steven W Lindsay, Clare Green, Balla Kandeh and Ulrike Fillinger

    Citation: Malaria Journal 2007 6:76

    Content type: Research

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  21. During blood feeding, the mosquito injects saliva into the vertebrate host. This saliva contains bioactive components which may play a role in pathogen transmission and in host-vector relationships by inducing...

    Authors: Sylvie Cornelie, Franck Remoue, Souleymane Doucoure, Tofene NDiaye, Francois-Xavier Sauvage, Denis Boulanger and Francois Simondon

    Citation: Malaria Journal 2007 6:75

    Content type: Research

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  22. Malaria rapid diagnostic tests (RDTs) are relatively simple to perform and provide results quickly for making treatment decisions. However, the accuracy and application of RDT results depends on several factor...

    Authors: Devanand Moonasar, Ameena Ebrahim Goga, John Frean, Philip Kruger and Daniel Chandramohan

    Citation: Malaria Journal 2007 6:74

    Content type: Research

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  23. Enhanced production of nitric oxide (NO) following upmodulation of the inducible isoform of NO synthase (iNOS) by haemozoin (HZ), inflammatory cytokines and LPS may provide protection against Plasmodium falciparu...

    Authors: Oleksii A Skorokhod, Evelin Schwarzer, Monica Ceretto and Paolo Arese

    Citation: Malaria Journal 2007 6:73

    Content type: Research

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  24. Sulphadoxine/sulphalene-pyrimethamine (SP) was adopted in Kenya as first line therapeutic for uncomplicated malaria in 1998. By the second half of 2003, there was convincing evidence that SP was failing and ha...

    Authors: Abdinasir A Amin, Dejan Zurovac, Beth B Kangwana, Joanne Greenfield, Dorothy N Otieno, Willis S Akhwale and Robert W Snow

    Citation: Malaria Journal 2007 6:72

    Content type: Research

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  25. Because of the belief that Nairobi is a low risk zone for malaria, little empirical data exists on malaria risk in the area. The aim of this study was to explore the risk of perceived malaria and some associat...

    Authors: Yazoumé Yé, Elizabeth Kimani-Murage, John Kebaso and Frederick Mugisha

    Citation: Malaria Journal 2007 6:71

    Content type: Research

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  26. The study investigated the pharmacokinetics of fosmidomycin when given alone and in combination with clindamycin in patients with acute uncomplicated falciparum malaria.

    Authors: Kesara Na-Bangchang, Ronnatrai Ruengweerayut, Juntra Karbwang, Anurak Chauemung and David Hutchinson

    Citation: Malaria Journal 2007 6:70

    Content type: Research

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  27. The overlap in geographical distribution of Plasmodium falciparum malaria and endemic Burkitt's lymphoma (eBL) – an aggressive Epstein-Barr virus (EBV)-associated B-cell tumour occurring almost exclusively in the...

    Authors: Godfred Futagbi, Jennifer E Welbeck, John Kweku A Tetteh, Lars Hviid and Bartholomew D Akanmori

    Citation: Malaria Journal 2007 6:69

    Content type: Research

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  28. The acceptability and efficacy of a new kit with a new formulation of quinine alkaloids designed for the intra-rectal administration in the treatment of non-per os malaria was assessed in the peripheral health...

    Authors: Mahamadou A Thera, Falaye Keita, Mahamadou S Sissoko, Oumar B Traoré, Drissa Coulibaly, Massambou Sacko, Valerie Lameyre, Jean Pascal Ducret and Ogobara Doumbo

    Citation: Malaria Journal 2007 6:68

    Content type: Research

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  29. Anaemic status is determined by haemoglobin using the HemoCue system or haematocrit measurements, and a threefold conversion is commonly used to equate the two measures (haemoglobin = haematocrit/3). The valid...

    Authors: Ilona A Carneiro, Chris J Drakeley, Seth Owusu-Agyei, Bruno Mmbando and Daniel Chandramohan

    Citation: Malaria Journal 2007 6:67

    Content type: Research

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  30. Sensitive detection of parasite surface antigens expressed on erythrocyte membranes is necessary to further analyse the molecular pathology of malaria. This study describes a modified biotin labelling/osmotic ...

    Authors: Lisa Sharling, Kordai MP Sowa, Joanne Thompson, Helen M Kyriacou and David E Arnot

    Citation: Malaria Journal 2007 6:66

    Content type: Methodology

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  31. Data concerning antimalarial combination treatment for uncomplicated malaria in Madagascar are largely lacking. Randomized clinical trial was designed to assess therapeutic efficacies of chloroquine (CQ), amod...

    Authors: Didier Ménard, Nohary Nina Harimanana Andrianina, Zakaherizo Ramiandrasoa, Arthur Randriamanantena, Noéline Rasoarilalao, Martial Jahevitra, Arsène Ratsimbasoa, Luciano Tuseo and Andrianirina Raveloson

    Citation: Malaria Journal 2007 6:65

    Content type: Research

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  32. Paroxysms are recurrent febrile episodes, characteristic of Plasmodium vivax infections, which coincide with the rupture of schizont-infected erythrocytes in the patients' circulation. The present study describes...

    Authors: Nadira Karunaweera, Deepani Wanasekara, Vishvanath Chandrasekharan, Kamini Mendis and Richard Carter

    Citation: Malaria Journal 2007 6:62

    Content type: Research

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  33. Intracellular malaria parasites leave their host erythrocytes to infect neighbouring cells after each cycle of asexual replication. No method is currently available for the direct quantification of parasite re...

    Authors: Svetlana Glushakova, Dan Yin, Nicole Gartner and Joshua Zimmerberg

    Citation: Malaria Journal 2007 6:61

    Content type: Methodology

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  34. Molecular techniques have facilitated the studies on genetic diversity of Plasmodium species particularly from field isolates collected directly from patients. The msp-1 and msp-2 are highly polymorphic markers a...

    Authors: Hema Joshi, Neena Valecha, Anju Verma, Asha Kaul, Prashant K Mallick, Sneh Shalini, Surendra K Prajapati, Surya K Sharma, Vas Dev, Sukla Biswas, Nutan Nanda, MS Malhotra, Sarala K Subbarao and Aditya P Dash

    Citation: Malaria Journal 2007 6:60

    Content type: Research

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  35. Immune responses to malaria blood stage infection are in general defective, with the need for long-term exposure to the parasite to achieve immunity, and with the development of immunopathology states such as ...

    Authors: Leonardo JM Carvalho, Maria F Ferreira-da-Cruz, Claudio T Daniel-Ribeiro, Marcelo Pelajo-Machado and Henrique L Lenzi

    Citation: Malaria Journal 2007 6:59

    Content type: Research

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  36. An assessment of the accuracy of Paracheck Pf®, a malaria rapid diagnostic test (RDT) detecting histidine rich protein 2 was undertaken amongst children aged 6–59 months in eastern Democratic Republic of Congo.

    Authors: Todd D Swarthout, Helen Counihan, Raphael Kabangwa K Senga and Ingrid van den Broek

    Citation: Malaria Journal 2007 6:58

    Content type: Research

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  37. Global malaria control strategies highlight the need to increase early uptake of effective antimalarials for childhood fevers in endemic settings, based on a presumptive diagnosis of malaria in this age group....

    Authors: Timothy O Abuya, Wilfred Mutemi, Baya Karisa, Sam A Ochola, Greg Fegan and Vicki Marsh

    Citation: Malaria Journal 2007 6:57

    Content type: Research

    Published on:

  38. The emergence of Anopheles populations capable of withstanding lethal doses of insecticides has weakened the efficacy of most insecticide based strategies of vector control and, has highlighted the need for devel...

    Authors: Rousseau F Djouaka, Adekunle A Bakare, Honore S Bankole, Julien MC MC Doannio, Hortense Kossou and Martin C Akogbeto

    Citation: Malaria Journal 2007 6:56

    Content type: Research

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  39. Nigeria's national standard has recently moved to artemisinin combination treatments for malaria. As clinicians in the private sector are responsible for attending a large proportion of the population ill with...

    Authors: Martin Meremikwu, Uduak Okomo, Chukwuemeka Nwachukwu, Angela Oyo-Ita, John Eke-Njoku, Joseph Okebe, Esu Oyo-Ita and Paul Garner

    Citation: Malaria Journal 2007 6:55

    Content type: Research

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  40. In the last five years, countries have been faced with changing their malaria treatment policy to an artemisinin-based combination therapy (ACT), many with no national data on which to base their decision. Thi...

    Authors: Maryline Bonnet, Cally Roper, Martine Félix, Léonie Coulibaly, Gabriel Mufuta Kankolongo and Jean Paul Guthmann

    Citation: Malaria Journal 2007 6:54

    Content type: Research

    Published on:

  41. A comprehensive malaria control intervention was initiated in February 2004 on Bioko Island, Equatorial Guinea. This manuscript reports on the continuous entomological monitoring of the indoor residual spray (...

    Authors: Brian L Sharp, Frances C Ridl, Dayanandan Govender, Jaime Kuklinski and Immo Kleinschmidt

    Citation: Malaria Journal 2007 6:52

    Content type: Research

    Published on:

  42. The origin of highly competent malaria vectors has been linked to productive larval habitats in the field, but there isn't solid quantitative or qualitative data to support it. To test this, the effect of larv...

    Authors: Bernard A Okech, Louis C Gouagna, Guiyun Yan, John I Githure and John C Beier

    Citation: Malaria Journal 2007 6:50

    Content type: Research

    Published on:

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