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  1. Long-lasting insecticidal nets (LLIN) are now standard for the prevention of malaria. However, only products with recommendation for public use from the World Health Organization should be used and this evalua...

    Authors: Albert Kilian, Wilson Byamukama, Olivier Pigeon, John Gimnig, Francis Atieli, Lizette Koekemoer and Natacha Protopopoff
    Citation: Malaria Journal 2011 10:299
  2. In Uganda, malaria and lymphatic filariasis (causative agent Wuchereria bancrofti) are transmitted by the same vector species of Anopheles mosquitoes, and thus are likely to share common environmental risk factor...

    Authors: Anna-Sofie Stensgaard, Penelope Vounatsou, Ambrose W Onapa, Paul E Simonsen, Erling M Pedersen, Carsten Rahbek and Thomas K Kristensen
    Citation: Malaria Journal 2011 10:298
  3. Roll Back Malaria (RBM) interventions such as insecticide-treated mosquito nets (ITN) and artemisinin-based combination therapy (ACT) have become implemented with different velocities in the endemic countries ...

    Authors: Claudia Beiersmann, Mamadou Bountogo, Justin Tiendrébeogo, Manuela De Allegri, Valérie R Louis, Boubacar Coulibaly, Maurice Yé and Olaf Mueller
    Citation: Malaria Journal 2011 10:296
  4. Anti-malarial drug resistance threatens to undermine efforts to eliminate this deadly disease. The resulting omnipresent requirement for drugs with novel modes of action prompted a national consortium initiati...

    Authors: John VW Becker, Marina M van der Merwe, Anna C van Brummelen, Pamisha Pillay, Bridget G Crampton, Edwin M Mmutlane, Chris Parkinson, Fanie R van Heerden, Neil R Crouch, Peter J Smith, Dalu T Mancama and Vinesh J Maharaj
    Citation: Malaria Journal 2011 10:295
  5. Despite the wide spread use of lumefantrine, there is no study reporting the detailed preclinical pharmacokinetics of lumefantrine. For the development of newer anti-malarial combination(s) and selection of be...

    Authors: Wahajuddin, Sheelendra P Singh, Kanumuri SR Raju, Asad Nafis, Sunil K Puri and Girish K Jain
    Citation: Malaria Journal 2011 10:293
  6. Plasmodium vivax is the most prevalent cause of human malaria in tropical regions outside the African continent. The lack of a routine continuous in vitro culture of this parasite makes it difficult to develop sp...

    Authors: Voravuth Somsak, Chairat Uthaipibull, Parichat Prommana, Somdet Srichairatanakool, Yongyuth Yuthavong and Sumalee Kamchonwongpaisan
    Citation: Malaria Journal 2011 10:291
  7. WHO guidelines for the treatment of young children with suspected malaria have recently changed from presumptive treatment to anti-malarial treatment guided by a blood slide or malaria rapid diagnostic test (R...

    Authors: George Mtove, Ilse CE Hendriksen, Ben Amos, Hedwiga Mrema, Victor Mandia, Alphaxard Manjurano, Florida Muro, Alma Sykes, Helena Hildenwall, Christopher JM Whitty and Hugh Reyburn
    Citation: Malaria Journal 2011 10:290
  8. Genetic diversity is a key factor that enables adaptation and persistence of natural populations towards environmental conditions. It is influenced by the interaction of a natural population's dynamics and the...

    Authors: Kija R Ng'habi, Bart GJ Knols, Yoosook Lee, Heather M Ferguson and Gregory C Lanzaro
    Citation: Malaria Journal 2011 10:289
  9. To improve effectiveness of malaria control interventions, it is essential to deepen the knowledge of contextual factors that govern people's practice for preventive and curative measures. The aim of this stud...

    Authors: Allassane F Ouattara, Giovanna Raso, Constant VA Edi, Jürg Utzinger, Marcel Tanner, Mamadou Dagnogo and Benjamin G Koudou
    Citation: Malaria Journal 2011 10:288
  10. In 2009, Santa Isabel Province in the Solomon Islands embarked on a malaria elimination programme. However, very little is known in the Province about the anopheline fauna, which species are vectors, their bio...

    Authors: Hugo Bugoro, Charlie Iro'ofa, Donna O Mackenzie, Allen Apairamo, Watson Hevalao, Sarah Corcoran, Albino Bobogare, Nigel W Beebe, Tanya L Russell, Cheng-Chen Chen and Robert D Cooper
    Citation: Malaria Journal 2011 10:287
  11. Malaria rapid diagnostic tests (RDTs) are now widely used for prompt on-site diagnosis in remote endemic areas where reliable microscopy is absent. Aberrant results, whereby negative test results occur at high...

    Authors: Jennifer Luchavez, Joanne Baker, Sheila Alcantara, Vicente Belizario Jr, Qin Cheng, James S McCarthy and David Bell
    Citation: Malaria Journal 2011 10:286
  12. To be effective, national malaria guidelines must be properly followed. This study evaluated nurses' practices in the management of uncomplicated malaria cases at a District Hospital. Its objective was to iden...

    Authors: Sophie Sarrassat, Richard Lalou, Moustapha Cissé and Jean-Yves Le Hesran
    Citation: Malaria Journal 2011 10:285
  13. Malaria Rapid Diagnostic Tests (RDTs) are widely used to diagnose malaria. The present study evaluated a new RDT, the Clearview® Malaria pLDH test targeting the pan-Plasmodium antigen lactate dehydrogenase (pLDH)...

    Authors: Sandrine Houzé, Véronique Hubert, Dorit Pessler Cohen, Baruch Rivetz and Jacques Le Bras
    Citation: Malaria Journal 2011 10:284
  14. Recently, Plasmodium falciparum parasites bearing Pfdhfr I164L single mutation were found in Madagascar. These new mutants may challenge the use of antifolates for the intermittent preventive treatment of malaria...

    Authors: Valérie Andriantsoanirina, Rémy Durand, Bruno Pradines, Eric Baret, Christiane Bouchier, Arsène Ratsimbasoa and Didier Ménard
    Citation: Malaria Journal 2011 10:283
  15. Reports of severe cases and increasing levels of drug resistance highlight the importance of improved Plasmodium vivax case management. Whereas monitoring P. vivax resistance to anti-malarial drug by in vivo and

    Authors: Céline Barnadas, David Kent, Lincoln Timinao, Jonah Iga, Laurie R Gray, Peter Siba, Ivo Mueller, Peter J Thomas and Peter A Zimmerman
    Citation: Malaria Journal 2011 10:282
  16. Following the development of resistance to anti-malarial mono-therapies, malaria endemic countries in Africa now use artemisinin-based combination therapy (ACT) as recommended first-line treatment for uncompli...

    Authors: Harriet Lawford, Dejan Zurovac, Laura O'Reilly, Sarah Hoibak, Alice Cowley, Stephen Munga, John Vulule, Elizabeth Juma, Robert W Snow and Richard Allan
    Citation: Malaria Journal 2011 10:281
  17. It is controversial to what degree α+-thalassaemia protects against episodes of uncomplicated malaria and febrile disease due to infections other than Plasmodium.

    Authors: Jacobien Veenemans, Esther JS Jansen, Amrish Y Baidjoe, Erasto V Mbugi, AyÅŸe Y Demir, Rob J Kraaijenhagen, Huub FJ Savelkoul and Hans Verhoef
    Citation: Malaria Journal 2011 10:280
  18. Malaria still remains a life-threatening disease worldwide causing between 190 and 311 million cases of malaria in 2008. Due to increased resistance to sulphadoxine-pyrimethamine (SP), the Ministry of Health i...

    Authors: Linda V Kalilani-Phiri, Douglas Lungu and Renia Coghlan
    Citation: Malaria Journal 2011 10:279
  19. Parasite clearance rates are important measures of anti-malarial drug efficacy. They are particularly important in the assessment of artemisinin resistance. The slope of the log-linear segment in the middle of...

    Authors: NJ White
    Citation: Malaria Journal 2011 10:278
  20. Malaria is one of the leading causes of sickness and death in the developing world, causing more than a million deaths and around 250 million new cases annually worldwide. The aim of this comprehensive survey ...

    Authors: Mahdi Mohammadi, Alireza Ansari-Moghaddam, Ahmad Raiesi, Fatemeh Rakhshani, Fatemeh Nikpour, Aliakbar Haghdost, Mansoor Ranjbar, Rahim Taghizadeh-Asl, Mohammad Sakeni, Reza Safari and Mehdi Saffari
    Citation: Malaria Journal 2011 10:277
  21. The characterization of malaria parasite populations circulating in an area is part of site characterization, as a basis for evaluating the impact of malaria interventions on genetic diversity, parasite specie...

    Authors: Pembe Issamou Mayengue, Mathieu Ndounga, Freddy Vladimir Malonga, Michel Bitemo and Francine Ntoumi
    Citation: Malaria Journal 2011 10:276
  22. Sulphadoxine-pyrimethamine, in combination with artesunate or amodiaquine, is recommended for the treatment of uncomplicated malaria and is being evaluated for intermittent preventive treatment. Yet, limited d...

    Authors: Mamadou M Tekete, Sékou Toure, Alfia Fredericks, Abdoul H Beavogui, Cheick PO Sangare, Alicia Evans, Peter Smith, Hamma Maiga, Zoumana I Traore, Ogobara K Doumbo, Karen I Barnes and Abdoulaye A Djimde
    Citation: Malaria Journal 2011 10:275
  23. Developing resistance towards existing anti-malarial therapies emphasize the urgent need for new therapeutic options. Additionally, many malaria drugs in use today have high toxicity and low therapeutic indice...

    Authors: David J Sullivan Jr, Nikola Kaludov and Martin N Martinov
    Citation: Malaria Journal 2011 10:274
  24. The control of malaria in schools is receiving increasing attention, but there remains currently no consensus as to the optimal intervention strategy. This paper analyses the costs of intermittent screening an...

    Authors: Thomas L Drake, George Okello, Kiambo Njagi, Katherine E Halliday, Matthew CH Jukes, Lindsay Mangham and Simon Brooker
    Citation: Malaria Journal 2011 10:273
  25. The influence of host genetics on susceptibility to Plasmodium falciparum malaria has been extensively studied over the past twenty years. It is now clear that malaria parasites have imposed strong selective forc...

    Authors: Adel Driss, Jacqueline M Hibbert, Nana O Wilson, Shareen A Iqbal, Thomas V Adamkiewicz and Jonathan K Stiles
    Citation: Malaria Journal 2011 10:271
  26. Various methods have been studied as replacement of human landing catches (HLC) for mosquito sampling in entomological studies on malaria transmission. Conflicting results have been obtained in comparing relat...

    Authors: Mamadou O Ndiath, Catherine Mazenot, Ablaye Gaye, Lassana Konate, Charles Bouganali, Ousmane Faye, Cheikh Sokhna and Jean-Francois Trape
    Citation: Malaria Journal 2011 10:270
  27. The different taxa belonging to Anopheles gambiae complex display phenotypic differences that may impact their contribution to malaria transmission. More specifically, their susceptibility to infection, resulting...

    Authors: Mamadou O Ndiath, Anna Cohuet, Ablaye Gaye, Lassana Konate, Catherine Mazenot, Ousmane Faye, Christian Boudin, Cheikh Sokhna and Jean-François Trape
    Citation: Malaria Journal 2011 10:269
  28. Decreased in vitro susceptibility to dihydroartemisinin (21.2 nM) and artesunate (16.3 nM) associated with decreased susceptibility or resistance to quinine (1131 nM), mefloquine (166 nM), lumefantrine (114 nM), ...

    Authors: Bruno Pradines, Lionel Bertaux, Christelle Pomares, Pascal Delaunay and Pierre Marty
    Citation: Malaria Journal 2011 10:268
  29. The role of brain oedema in the pathophysiology of cerebral malaria is controversial. Coma associated with severe Plasmodium falciparum malaria is multifactorial, but associated with histological evidence of para...

    Authors: Isabelle M Medana, Nicholas PJ Day, Navakanit Sachanonta, Nguyen TH Mai, Arjen M Dondorp, Emsri Pongponratn, Tran T Hien, Nicholas J White and Gareth DH Turner
    Citation: Malaria Journal 2011 10:267
  30. Malaria remains a global public health challenge. It is widely believed that an effective vaccine against malaria will need to incorporate multiple antigens from the various stages of the parasite's complex li...

    Authors: Harini D de Silva, Suha Saleh, Svetozar Kovacevic, Lina Wang, Casilda G Black, Magdalena Plebanski and Ross L Coppel
    Citation: Malaria Journal 2011 10:266
  31. During the past decade the malaria control community has been successful in dramatically increasing the number of households that own mosquito nets. However, as many as half of nets already in households go un...

    Authors: Carol A Baume and Ana Cláudia Franca-Koh
    Citation: Malaria Journal 2011 10:265
  32. In human malaria, the naturally-acquired immune response can result in either the elimination of the parasite or a persistent response mediated by cytokines that leads to immunopathology. The cytokines are res...

    Authors: Tiago S Medina, Sheyla PT Costa, Maria D Oliveira, Ana M Ventura, José M Souza, Tassia F Gomes, Antonio CR Vallinoto, Marinete M Póvoa, João S Silva and Maristela G Cunha
    Citation: Malaria Journal 2011 10:264
  33. Artesunate (AS) is a clinically versatile artemisinin derivative utilized for the treatment of mild to severe malaria infection. Given the therapeutic significance of AS and the necessity of appropriate AS dos...

    Authors: Carrie A Morris, Stephan Duparc, Isabelle Borghini-Fuhrer, Donald Jung, Chang-Sik Shin and Lawrence Fleckenstein
    Citation: Malaria Journal 2011 10:263
  34. The main vector of malaria in Solomon Islands is Anopheles farauti, which has a mainly coastal distribution. In Northern Guadalcanal, Solomon Islands, high densities of An. farauti are supported by large brackish...

    Authors: Hugo Bugoro, Jeffery Hii, Tanya L Russell, Robert D Cooper, Benny KK Chan, Charles Iro'ofa, Charles Butafa, Allen Apairamo, Albino Bobogare and Cheng-Chen Chen
    Citation: Malaria Journal 2011 10:262
  35. Insecticide resistance monitoring is essential to help national programmers to implement more effective and sustainable malaria control strategies in endemic countries. This study reported the spatial and seas...

    Authors: Innocent Djègbè, Olayidé Boussari, Aboubakar Sidick, Thibaud Martin, Hilary Ranson, Fabrice Chandre, Martin Akogbéto and Vincent Corbel
    Citation: Malaria Journal 2011 10:261
  36. Zambia has achieved significant reductions in the burden of malaria through a strategy of "scaling-up" effective interventions. Progress toward ultimate malaria elimination will require sustained prevention co...

    Authors: Ryan G Davis, Aniset Kamanga, Carlos Castillo-Salgado, Nnenna Chime, Sungano Mharakurwa and Clive Shiff
    Citation: Malaria Journal 2011 10:260
  37. Placental malaria and pre-eclampsia occur frequently in women in tropics and are leading causes of maternal and perinatal morbidities and mortality. Few data exist concerning the interaction between placental ...

    Authors: Ishag Adam, Elhassan M Elhassan, Ahmed A Mohmmed, Magdi M Salih and Mustafa I Elbashir
    Citation: Malaria Journal 2011 10:258
  38. The reemergence of Plasmodium vivax in South Korea since 1993 represents a serious public health concern. Despite the importance in understanding genetic diversity for control strategies, however, studies remain ...

    Authors: Hajime Honma, Jung-Yeon Kim, Nirianne MQ Palacpac, Toshihiro Mita, Wonja Lee, Toshihiro Horii and Kazuyuki Tanabe
    Citation: Malaria Journal 2011 10:257
  39. Rapid and fast acting anti-malarials are essential to treat severe malaria. Quinine has been the only option for parenteral therapy until recently. While current evidence shows that intravenous artesunate is m...

    Authors: Jakob P Cramer, Rogelio López-Vélez, Gerd D Burchard, Martin P Grobusch and Peter J de Vries
    Citation: Malaria Journal 2011 10:256
  40. Since 2000, under the Fifth and subsequent Framework Programmes, the European Commission has funded research to spur the development of a malaria vaccine. This funding has contributed to the promotion of an in...

    Authors: Regitze L Thøgersen, Anthony A Holder, Adrian VS Hill, David E Arnot, Egeruan B Imoukhuede and Odile Leroy
    Citation: Malaria Journal 2011 10:255
  41. In patients with malaria mixed species infections are common and under reported. In PCR studies conducted in Asia mixed infection rates often exceed 20%. In South-East Asia, approximately one third of patients...

    Authors: Mallika Imwong, Supatchara Nakeesathit, Nicholas PJ Day and Nicholas J White
    Citation: Malaria Journal 2011 10:253
  42. Immune evasion and drug resistance in malaria have been linked to chromosomal recombination and gene copy number variation (CNV). These events are ideally studied using comparative genomic analyses; however in...

    Authors: Matthew C Riley, Benjamin C Kirkup Jr, Jake D Johnson, Emil P Lesho and Christian F Ockenhouse
    Citation: Malaria Journal 2011 10:252

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