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  1. Sequential analysis enables repeated statistical analyses to be performed throughout a trial recruitment period, while maintaining a pre-specified power and type I error. Thus the trial can be stopped as soon ...

    Authors: Stéphane Ranque, Sékéné Badiaga, Jean Delmont and Philippe Brouqui

    Citation: Malaria Journal 2002 1:13

    Content type: Methodology

    Published on:

  2. The increasing levels of Plasmodium falciparum resistance to chloroquine (CQ) in Thailand have led to the use of alternative antimalarials, which are at present also becoming ineffective. In this context, any str...

    Authors: Dinora Lopes, Kanchana Rungsihirunrat, Fátima Nogueira, Aree Seugorn, José Pedro Gil, Virgilio E do Rosário and Pedro Cravo

    Citation: Malaria Journal 2002 1:12

    Content type: Research

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  3. Results from numerous studies point convincingly to correlations between mutations at selected genes and phenotypic resistance to antimalarials in Plasmodium falciparum isolates. In order to move molecular assays...

    Authors: Tomas Jelinek, Gabriele Peyerl-Hoffmann, Nikolai Mühlberger, Ole Wichmann, Michael Wilhelm, Nadja Schmider, Martin P Grobusch, Frank von Sonnenburg, Joaquim Gascon, Hermann Laferl, Christoph Hatz, Michael Alifrangis, Gerd Burchard, Paul McWhinney, Marco Schulze, Herwig Kollaritsch…

    Citation: Malaria Journal 2002 1:11

    Content type: Research

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  4. Plasmodium-refractory mosquitoes are being rapidly developed for malaria control but will only succeed if they can successfully compete for mates when released into the wild. Pre-copulatory behavioural traits mai...

    Authors: FM Okanda, A Dao, BN Njiru, J Arija, HA Akelo, Y Touré, A Odulaja, JC Beier, JI Githure, G Yan, LC Gouagna, BGJ Knols and GF Killeen

    Citation: Malaria Journal 2002 1:10

    Content type: Research

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  5. Much communicable disease control research has had little impact on local control programme policy and practice for want of an operational component. The operational research model – the systematic search for ...

    Authors: David N Durrheim, Richard Speare and Anthony D Harries

    Citation: Malaria Journal 2002 1:9

    Content type: Research

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  6. Based on sensitivity analysis of the MacDonald-Ross model, it has long been argued that the best way to reduce malaria transmission is to target adult female mosquitoes with insecticides that can reduce the lo...

    Authors: Gerry F Killeen, Ulrike Fillinger and Bart GJ Knols

    Citation: Malaria Journal 2002 1:8

    Content type: Opinion

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  7. Plasmodium falciparum erythrocyte membrane protein-1, a variant antigen of the malaria parasite, is potentially a target for the immune response. It would be important to determine whether there are CD4 T cells t...

    Authors: Latifu A Sanni, Catherine EM Allsopp, Lieke Reubsaet, Ambaliou Sanni, Chris Newbold, Virander S Chauhan and Jean Langhorne

    Citation: Malaria Journal 2002 1:7

    Content type: Methodology

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  8. In host erythrocytes, the malaria parasite must contend with ion and drug transport across three membranes; its own plasma membrane, the parasitophorous membrane and the host plasma membrane. Isolation of pure...

    Authors: Laurence M Elandalloussi and Pete J Smith

    Citation: Malaria Journal 2002 1:6

    Content type: Methodology

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  9. Reversible protein phosphorylation is relatively unexplored in the intracellular protozoa of the Apicomplexa family that includes the genus Plasmodium, to which belong the causative agents of malaria. Members of ...

    Authors: Rajinder Kumar, Brian Adams, Anja Oldenburg, Alla Musiyenko and Sailen Barik

    Citation: Malaria Journal 2002 1:5

    Content type: Research

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  10. We report the first in vitro and genetic confirmation of Malarone® (GlaxoSmithKline; atovaquone and proguanil hydrochloride) resistance in Plasmodium falciparum acquired in Africa. On presenting with malaria two ...

    Authors: Quinton L Fivelman, Geoffrey A Butcher, Ipemida S Adagu, David C Warhurst and Geoffrey Pasvol

    Citation: Malaria Journal 2002 1:1

    Content type: Case report

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