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  1. The development of safe, effective and affordable drug combinations against malaria in Africa is a public health priority. Methylene blue (MB) has a similar mode of action as chloroquine (CQ) and has moreover ...

    Authors: Peter E Meissner, Germain Mandi, Boubacar Coulibaly, Steffen Witte, Théophile Tapsoba, Ulrich Mansmann, Jens Rengelshausen, Wolfgang Schiek, Albrecht Jahn, Ingeborg Walter-Sack, Gerd Mikus, Jürgen Burhenne, Klaus-Dieter Riedel, R Heiner Schirmer, Bocar Kouyaté and Olaf Müller

    Citation: Malaria Journal 2006 5:84

    Content type: Research

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  2. The naturally-acquired immune response to Plasmodium vivax variant antigens (VIR) was evaluated in individuals exposed to malaria and living in different endemic areas for malaria in the north of Brazil.

    Authors: Tatiane R Oliveira, Carmen Fernandez-Becerra, Maria Carolina S Jimenez, Hernando A Del Portillo and Irene S Soares

    Citation: Malaria Journal 2006 5:83

    Content type: Research

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  3. In vitro and in vivo resistance of Plasmodium falciparum to atovaquone or atovaquone-proguanil hydrochloride combination has been associated to two point mutations in the parasite cytochrome b (cytb) gene (Tyr268...

    Authors: Christian T Happi, Grace O Gbotosho, Onikepe A Folarin, Danny Milner, Ousmane Sarr, Akintunde Sowunmi, Dennis E Kyle, Wilbur K Milhous, Dyann F Wirth and Ayoade MJ Oduola

    Citation: Malaria Journal 2006 5:82

    Content type: Research

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  4. Artemisinin-containing therapies are highly effective against Plasmodium falciparum malaria. Insufficient numbers of tablets and inadequate package inserts result in sub-optimal dosing and possible treatment fail...

    Authors: Yves Jackson, François Chappuis, Louis Loutan and Walter Taylor

    Citation: Malaria Journal 2006 5:81

    Content type: Research

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  5. Decisions concerning malaria treatment depend on species identification causing disease. Microscopy is most frequently used, but at low parasitaemia (<20 parasites/μl) the technique becomes less sensitive and ...

    Authors: Petra F Mens, Gerard J Schoone, Piet A Kager and Henk DFH Schallig

    Citation: Malaria Journal 2006 5:80

    Content type: Methodology

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  6. The main objective of this study was to assess the quality of home malaria management with pre-packaged chloroquine in two areas in the Moramanga district of Madagascar. The knowledge, attitude and practices o...

    Authors: Arsène Ratsimbasoa, Milijaona Randrianarivelojosia, Pascal Millet, Jean Louis Soarès, Leon Rabarijaona, Benjamin Rakotoson, Denis Malvy and Didier Ménard

    Citation: Malaria Journal 2006 5:79

    Content type: Research

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  7. Malaria epidemics in highland areas of East Africa have caused considerable morbidity and mortality in the past two decades. Knowledge of "hotspot" areas of high malaria incidence would allow for focused preve...

    Authors: Kacey C Ernst, Samson O Adoka, Dickens O Kowuor, Mark L Wilson and Chandy C John

    Citation: Malaria Journal 2006 5:78

    Content type: Research

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  8. Recent field studies indicated that insecticide-treated bednets (ITNs) maintain their efficacy despite a high frequency of the knock-down resistance (kdr) gene in Anopheles gambiae populations. It was essential t...

    Authors: Mouhamadou Chouaibou, Frédéric Simard, Fabrice Chandre, Josiane Etang, Frédéric Darriet and Jean-Marc Hougard

    Citation: Malaria Journal 2006 5:77

    Content type: Research

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  9. Malaria imposes significant costs on households and the poor are disproportionately affected. However, cost data are often from quantitative surveys with a fixed recall period. They do not capture costs that u...

    Authors: Jane M Chuma, Michael Thiede and Catherine S Molyneux

    Citation: Malaria Journal 2006 5:76

    Content type: Research

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  10. Sentinel site surveillance of antimalarials by in-vivo therapeutic efficacy studies in Zambia is one of the key activities ear-marked for monitoring and evaluation. The studies are conducted annually in order ...

    Authors: Pascalina Chanda, Moonga Hawela, Mabvuto Kango and Naawa Sipilanyambe

    Citation: Malaria Journal 2006 5:75

    Content type: Research

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  11. In Zambia, unacceptably high resistance to commonly used antimalarial drugs prompted the choice of artemether-lumefantrine (AL) as first line treatment for uncomplicated Plasmodium falciparum malaria. Although th...

    Authors: Modest Mulenga, Jean-Pierre Van geertruyden, Lawrence Mwananyanda, Victor Chalwe, Filip Moerman, Roma Chilengi, Chantal Van Overmeir, Jean-Claude Dujardin and Umberto D'Alessandro

    Citation: Malaria Journal 2006 5:73

    Content type: Research

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  12. Host susceptibility to P.falciparum is critical for understanding malaria in pregnancy, its consequences for the mother and baby, and for improving malaria control in pregnant women. Yet host genetic factors whic...

    Authors: María-Paz Loscertales and Bernard J Brabin

    Citation: Malaria Journal 2006 5:72

    Content type: Research

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  13. Plasmodium vivax malaria accounts for approximately 60% of malaria cases in Kolkata, India. There has been limited information on the genotypic polymorphism of P. vivax in this malaria endemic area. Three highly ...

    Authors: Jung-Ryong Kim, Mallika Imwong, Amitabha Nandy, Kesinee Chotivanich, Apichart Nontprasert, Naowarat Tonomsing, Ardhendu Maji, Manjulika Addy, Nick PJ Day, Nicholas J White and Sasithon Pukrittayakamee

    Citation: Malaria Journal 2006 5:71

    Content type: Research

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  14. Insecticide-treated bed nets (ITNs) are known to be highly effective in reducing malaria morbidity and mortality. The effectiveness of ITNs is largely influenced by behavioural factors and not much is known re...

    Authors: Claudia Frey, Corneille Traoré, Manuela De Allegri, Bocar Kouyaté and Olaf Müller

    Citation: Malaria Journal 2006 5:70

    Content type: Research

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  15. The population dynamics of Plasmodium sporogony within mosquitoes consists of an early phase where parasite abundance decreases during the transition from gametocyte to oocyst, an intermediate phase where parasit...

    Authors: Gabriela E Zollner, Narong Ponsa, Gabriel W Garman, Shreekanta Poudel, Jeffrey A Bell, Jetsumon Sattabongkot, Russell E Coleman and Jefferson A Vaughan

    Citation: Malaria Journal 2006 5:68

    Content type: Research

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  16. The virulence of Plasmodium falciparum relates in part to the cytoadhesion characteristics of parasitized erythrocytes but the molecular basis of the different qualitative and quantitative binding phenotypes is i...

    Authors: Yang Wu and Alister Craig

    Citation: Malaria Journal 2006 5:67

    Content type: Methodology

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  17. Malaria has recently re-emerged as a public health burden in Colombia. Although the problem seems to be climate-driven, there remain significant gaps of knowledge in the understanding of the complexity of mala...

    Authors: Daniel Ruiz, Germán Poveda, Iván D Vélez, Martha L Quiñones, Guillermo L Rúa, Luz E Velásquez and Juan S Zuluaga

    Citation: Malaria Journal 2006 5:66

    Content type: Research

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  18. In Sudan, chloroquine (CQ) remains the most frequently used drug for falciparum malaria for more than 40 years. The change to artemisinin-based combination therapy (ACT) was initiated in 2004 using the co-blis...

    Authors: EM Malik, TA Mohamed, KA Elmardi, RM Mowien, AH Elhassan, SB Elamin, AA Mannan and ES Ahmed

    Citation: Malaria Journal 2006 5:65

    Content type: Case study

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  19. A high prevalence of spherocytes was detected in blood smears of children enrolled in a case control study conducted in the malaria holoendemic Lake Victoria basin. It was speculated that the spherocytes refle...

    Authors: Samuel B Anyona, Stanley L Schrier, Charity W Gichuki and John N Waitumbi

    Citation: Malaria Journal 2006 5:64

    Content type: Research

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  20. Malaria prevention programmes should be based in part on knowledge of why some individuals use bednets while others do not. This paper identifies factors and characteristics of women that affect bednet use amo...

    Authors: Natalie De La Cruz, Benjamin Crookston, Kirk Dearden, Bobbi Gray, Natasha Ivins, Stephen Alder and Robb Davis

    Citation: Malaria Journal 2006 5:61

    Content type: Research

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  21. Effective management of malaria in children under the age of 5 requires mothers to seek, obtain, and use medication appropriately. This is linked to timely decision, accessibility, correct use of the drugs and...

    Authors: Elfatih Mohamed Malik, Kamal Hanafi, Salah Hussein Ali, Eldirdieri Salim Ahmed and Khalid Awad Mohamed

    Citation: Malaria Journal 2006 5:60

    Content type: Research

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  22. A six-dose antimalarial regimen of artemether-lumefantrine (A/L) may soon become one of the most widely used drug combination in Africa, despite possible constraints with adherence and poor absorption due to i...

    Authors: Francesco Checchi, Patrice Piola, Carole Fogg, Francis Bajunirwe, Samuel Biraro, Francesco Grandesso, Eugene Ruzagira, Joseph Babigumira, Isaac Kigozi, James Kiguli, Juliet Kyomuhendo, Laurent Ferradini, Walter RJ Taylor and Jean-Paul Guthmann

    Citation: Malaria Journal 2006 5:59

    Content type: Research

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  23. The current malaria control strategy of WHO centres on early diagnosis and prompt treatment using effective drugs. Children with severe malaria are often brought late to health facilities and traditional healt...

    Authors: Emmanuel A Makundi, Hamisi M Malebo, Paulo Mhame, Andrew Y Kitua and Marian Warsame

    Citation: Malaria Journal 2006 5:58

    Content type: Research

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  24. Molecular markers of insecticide resistance can provide sensitive indicators of resistance development in malaria vector populations. Monitoring of insecticide resistance in vector populations is an important ...

    Authors: Manisha A Kulkarni, Mark Rowland, Michael Alifrangis, Frank W Mosha, Johnson Matowo, Robert Malima, Justin Peter, Eliningaya Kweka, Issa Lyimo, Stephen Magesa, Ali Salanti, Manfred E Rau and Chris Drakeley

    Citation: Malaria Journal 2006 5:56

    Content type: Methodology

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  25. As malaria becomes increasingly drug resistant and more costly to treat, there is increasing urgency to develop effective vaccines. In comparison to other stages of the malaria lifecycle, sexual stage antigens...

    Authors: Jack S Richards, Nicholas J MacDonald and Damon P Eisen

    Citation: Malaria Journal 2006 5:55

    Content type: Research

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  26. In Ethiopia, malaria is caused by both Plasmodium falciparum and Plasmodium vivax. Drug resistance of P. falciparum to sulfadoxine-pyrimethamine (SP) and chloroquine (CQ) is frequent and intense in some areas.

    Authors: Mirjam Schunk, Wondimagegn P Kumma, Isabel Barreto Miranda, Maha E Osman, Susanne Roewer, Abraham Alano, Thomas Löscher, Ulrich Bienzle and Frank P Mockenhaupt

    Citation: Malaria Journal 2006 5:54

    Content type: Research

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  27. Cellular interactions elicited by Plasmodium falciparum erythrocyte membrane protein antigen 1 (PfEMP1) are brought about by multiple DBL (Duffy binding like), CIDR (cysteine-rich interdomain region) and C2 domai...

    Authors: Sanjay Ahuja, Satpal Ahuja, Qijun Chen and Mats Wahlgren

    Citation: Malaria Journal 2006 5:52

    Content type: Methodology

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  28. During the Soviet era, malaria was close to eradication in Tajikistan. Since the early 1990s, the disease has been on the rise and has become endemic in large areas of southern and western Tajikistan. The stan...

    Authors: Cornelia E Rebholz, Anette J Michel, Daniel A Maselli, Karimov Saipphudin and Kaspar Wyss

    Citation: Malaria Journal 2006 5:51

    Content type: Research

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  29. A reduction in the therapeutic efficacy of chloroquine (CQ) and sulphadoxine-pyrimethamine (SP) has recently been observed in Burkina Faso. As these two drugs are used in pregnancy, their efficacy in pregnant ...

    Authors: Sheick Oumar Coulibaly, Désiré Nezien, Salifou Traoré, Bibiane Koné and Pascal Magnussen

    Citation: Malaria Journal 2006 5:49

    Content type: Research

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  30. A large investment is required to develop, license and deploy a new antimalarial drug. Too often, that investment has been rapidly devalued by the selection of parasite populations resistant to the drug action...

    Authors: Carol Hopkins Sibley and Pascal Ringwald

    Citation: Malaria Journal 2006 5:48

    Content type: Review

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  31. Reliable mortality data are a prerequisite for planning health interventions, yet such data are often not available in developing countries, particularly in sub-Saharan Africa (SSA). Demographic surveillance s...

    Authors: Gaël P Hammer, Florent Somé, Olaf Müller, Gisela Kynast-Wolf, Bocar Kouyaté and Heiko Becher

    Citation: Malaria Journal 2006 5:47

    Content type: Research

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  32. An estimated 40 % of the population in Benin lives in urban areas. The purpose of the study was to estimate malaria endemicity and the fraction of malaria-attributable fevers in health facilities in Cotonou.

    Authors: Shr-Jie Wang, Christian Lengeler, Thomas A Smith, Penelope Vounatsou, Martin Akogbeto and Marcel Tanner

    Citation: Malaria Journal 2006 5:45

    Content type: Research

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  33. There is much emphasis on social marketing as a means of scaling up coverage with insecticide-treated nets and the question has arisen whether nets provided free-of-charge will be looked after by householders.

    Authors: CA Maxwell, RT Rwegoshora, SM Magesa and CF Curtis

    Citation: Malaria Journal 2006 5:44

    Content type: Opinion

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  34. The therapeutic efficacy of artesunate plus amodiaquine and artemether/lumefantrine were assessed in an area of Nigeria with high levels of Plasmodium falciparum resistance to chloroquine and sulphadoxine-pyrimet...

    Authors: Martin Meremikwu, Ambrose Alaribe, Regina Ejemot, Angela Oyo-Ita, John Ekenjoku, Chukwuemeka Nwachukwu, Donald Ordu and Emmanuel Ezedinachi

    Citation: Malaria Journal 2006 5:43

    Content type: Research

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  35. One year ago, the authors of this article reported in this journal on the malaria situation in Sri Lanka prior to the tsunami that hit on 26 December 2004, and estimated the likelihood of a post-tsunami malari...

    Authors: Olivier JT Briët, Gawrie NL Galappaththy, Priyanie H Amerasinghe and Flemming Konradsen

    Citation: Malaria Journal 2006 5:42

    Content type: Commentary

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  36. In 2002, home-based management of fever (HBMF) was introduced in Uganda, to improve access to prompt, effective antimalarial treatment of all fevers in children under 5 years. Implementation is through communi...

    Authors: Jan H Kolaczinski, Naptalis Ojok, John Opwonya, Sylvia Meek and Andrew Collins

    Citation: Malaria Journal 2006 5:40

    Content type: Research

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  37. The successful development of odour-baited trapping systems for mosquitoes depends on the identification of behaviourally active semiochemicals, besides the design and operating principles of such devices. A l...

    Authors: Basilio N Njiru, Wolfgang R Mukabana, Willem Takken and Bart GJ Knols

    Citation: Malaria Journal 2006 5:39

    Content type: Research

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  38. Malaria remains a major public health threat to more than 600 million Africans and its control is recognized as critical to achieving the Millennium Development Goals. The greatest burden of malaria in Africa ...

    Authors: Emily K Grover-Kopec, M Benno Blumenthal, Pietro Ceccato, Tufa Dinku, Judy A Omumbo and Stephen J Connor

    Citation: Malaria Journal 2006 5:38

    Content type: Commentary

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  39. Insecticide-treated nets (ITNs) are an effective and cost-effective means of malaria control. Scaling-up coverage of ITNs is challenging. It requires substantial resources and there are a number of strategies ...

    Authors: Jan Kolaczinski and Kara Hanson

    Citation: Malaria Journal 2006 5:37

    Content type: Review

    Published on:

  40. As efforts are currently underway to roll-out insecticide-treated bednets (ITNs) to populations within malarious areas in Africa, there is an unprecedented need for data to measure the effectiveness of such pr...

    Authors: Thomas P Eisele, Kate Macintyre, Josh Yukich and Tewolde Ghebremeskel

    Citation: Malaria Journal 2006 5:36

    Content type: Research

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  41. The associations between the immatures of Anopheles gambiae s.s. (Diptera: Culicidae), its M and S forms, and Anopheles arabiensis among and within larval breeding habitats in Banambani, Mali were investigated un...

    Authors: Frances E Edillo, Frederic Tripét, Yeya T Touré, Gregory C Lanzaro, Guimogo Dolo and Charles E Taylor

    Citation: Malaria Journal 2006 5:35

    Content type: Research

    Published on:

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