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  1. The receptors for adhesion of Plasmodium falciparum-infected red blood cells (RBC) in the placenta have been identified as chondroitin-4-sulphate (C4S) proteoglycans, and the more sulphate-rich chondroitin oligos...

    Authors: Sumit Bhattacharyya, Kemal Solakyildirim, Zhenqing Zhang, Robert J Linhardt and Joanne K Tobacman
    Citation: Malaria Journal 2009 8:303
  2. A key component of the malaria elimination strategy in Solomon Islands (SI) is widespread coverage of long-lasting insecticidal nets (LLINs). The success of this strategy is dependent on LLIN acceptability and...

    Authors: Jo-An Atkinson, Albino Bobogare, Andrew Vallely, Leonard Boaz, Gerard Kelly, William Basifiri, Simon Forsyth, Peter Baker, Bridget Appleyard, Hilson Toaliu and Gail Williams
    Citation: Malaria Journal 2009 8:298
  3. The gametocyte sex ratio of Plasmodium falciparum, defined as the proportion of gametocytes that are male, may influence transmission but little is known of the effects of mefloquine or artesunate-mefloquine on g...

    Authors: Akintunde Sowunmi, Oluchi O Nkogho, Titilope M Okuboyejo, Grace O Gbotosho, Christian T Happi and Elsie O Adewoye
    Citation: Malaria Journal 2009 8:297
  4. Malaria is an important threat to travelers visiting endemic regions. The risk of acquiring malaria is complex and a number of factors including transmission intensity, duration of exposure, season of the year...

    Authors: Eduardo Massad, Ronald H Behrens, Marcelo N Burattini and Francisco AB Coutinho
    Citation: Malaria Journal 2009 8:296
  5. Severe and cerebral malaria are associated with endothelial activation. Angiopoietin-1 (ANG-1) and angiopoietin-2 (ANG-2) are major regulators of endothelial activation and integrity. The aim of this study was...

    Authors: Andrea L Conroy, Erin I Lafferty, Fiona E Lovegrove, Srivicha Krudsood, Noppadon Tangpukdee, W Conrad Liles and Kevin C Kain
    Citation: Malaria Journal 2009 8:295
  6. Recently developed Sybr Green-based in vitro Plasmodium falciparum drug sensitivity assays provide an attractive alternative to current manual and automated methods. The present study evaluated flow cytometry mea...

    Authors: Stephan Karl, Rina PM Wong, Tim G St Pierre and Timothy ME Davis
    Citation: Malaria Journal 2009 8:294
  7. Palutop+4 (All. Diag, Strasbourg, France), a four-band malaria rapid diagnostic test (malaria RDT) targeting the histidine-rich protein 2 (HRP-2), Plasmodium vivax- specific parasite lactate dehydrogenase (Pv-pLD...

    Authors: David PJ van Dijk, Philippe Gillet, Erika Vlieghe, Lieselotte Cnops, Marjan van Esbroeck and Jan Jacobs
    Citation: Malaria Journal 2009 8:293
  8. Whiles awaiting for the arrival of an effective and affordable malaria vaccine, there is a need to make use of the available control tools to reduce malaria risk, especially in children under five years and pr...

    Authors: Collins K Ahorlu, Kwadwo A Koram, Atsu K Seakey and Mitchell G Weiss
    Citation: Malaria Journal 2009 8:292
  9. While the federal state of Amazonas bears the highest risk for malaria in Venezuela (2007: 68.4 cases/1000 inhabitants), little comprehensive information about the malaria situation is available from this area...

    Authors: Wolfram G Metzger, Anibal M Giron, Sarai Vivas-Martínez, Julio González, Antonio J Charrasco, Benjamin G Mordmüller and Magda Magris
    Citation: Malaria Journal 2009 8:291
  10. Interleukin-12 (IL-12), a heterodimeric cytokine composed of p35 and p40 subunits, has been thought to play an important role in the pathogenesis of malaria. The IL-12p40 subunit is encoded by the IL12B gene. An

    Authors: Izumi Naka, Jintana Patarapotikul, Katsushi Tokunaga, Hathairad Hananantachai, Naoyuki Tsuchiya and Jun Ohashi
    Citation: Malaria Journal 2009 8:290
  11. Halofantrine (HF) was considered an effective and safe treatment for multi-drug resistant falciparum malaria until 1993, when the first case of drug-associated death was reported. Since then, numerous studies ...

    Authors: Olivier Bouchaud, Patrick Imbert, Jean Etienne Touze, Alex NO Dodoo, Martin Danis and Fabrice Legros
    Citation: Malaria Journal 2009 8:289
  12. An outbreak of malaria in Naxalbari, West Bengal, India, in 2005 was investigated to understand determinants and propose control measures. Malaria cases were slide-confirmed. Methods included calculation of an...

    Authors: Puran K Sharma, Ramakrishnan Ramanchandran, Yvan J Hutin, Raju Sharma and Mohan D Gupte
    Citation: Malaria Journal 2009 8:288
  13. Malaria endemicity in Zanzibar has reached historically low levels, and the epidemiology of malaria transmission is in transition. To capitalize on these gains, Zanzibar has commissioned a feasibility assessme...

    Authors: Andrew J Tatem, Youliang Qiu, David L Smith, Oliver Sabot, Abdullah S Ali and Bruno Moonen
    Citation: Malaria Journal 2009 8:287
  14. The IL4-590 gene polymorphism has been shown to be associated with elevated levels of anti-Plasmodium falciparum IgG antibodies and parasite intensity in the malaria protected Fulani of West Africa. This study ai...

    Authors: Piyatida Tangteerawatana, Hedvig Perlmann, Masashi Hayano, Thareerat Kalambaheti, Marita Troye-Blomberg and Srisin Khusmith
    Citation: Malaria Journal 2009 8:286
  15. In order to provide a cost-effective tool to analyse pharmacogenetic markers in malaria treatment, DNA microarray technology was compared with sequencing of polymerase chain reaction (PCR) fragments to detect ...

    Authors: Eva Maria Hodel, Serej D Ley, Weihong Qi, Frédéric Ariey, Blaise Genton and Hans-Peter Beck
    Citation: Malaria Journal 2009 8:285
  16. Accurate laboratory diagnosis of malaria species in returning travelers is paramount in the treatment of this potentially fatal infectious disease.

    Authors: Krishna Khairnar, Donald Martin, Rachel Lau, Filip Ralevski and Dylan R Pillai
    Citation: Malaria Journal 2009 8:284
  17. In the absence of large scale, organized vector control programmes, individual protective measures against mosquitoes are essential for reducing the transmission of diseases like malaria. Knowledge of the type...

    Authors: Shelby S Yamamoto, Valérie R Louis, Ali Sié and Rainer Sauerborn
    Citation: Malaria Journal 2009 8:283
  18. The malaria vector and non-vector species of the Anopheles funestus group are morphologically very similar and accurate identification is required as part of effective control strategies. In the past, this has re...

    Authors: Samuel B Vezenegho, Chris Bass, Mirel Puinean, Martin S Williamson, Linda M Field, Maureen Coetzee and Lizette L Koekemoer
    Citation: Malaria Journal 2009 8:282
  19. Malaria is endemic in India with an estimated 70-100 million cases each year (1.6-1.8 million reported by NVBDCP); of this 50-55% are Plasmodium vivax and 45-50% Plasmodium falciparum. A recent study on malaria i...

    Authors: Vinod P Sharma
    Citation: Malaria Journal 2009 8:281
  20. Should the Kalimbe (a traditional Amerindian loincloth) be banned, based on its association with an increased risk of malaria? Studies on malaria conducted on Amerindian children in the Oyapock region, French ...

    Authors: Bernard Carme
    Citation: Malaria Journal 2009 8:280
  21. Improvements on malarial diagnostic methods are currently needed for the correct detection in low-density Plasmodium falciparum infections. Microfluorimetric DNA-based assays have been previously used for evaluat...

    Authors: Carlos Moneriz, Patricia Marín-García, José M Bautista, Amalia Diez and Antonio Puyet
    Citation: Malaria Journal 2009 8:279
  22. Malaria is a major public health problem in French Guiana, where Plasmodium vivax has become the dominant malaria species since 2000. As in others endemic areas, it is important to specify the pattern of vivax ma...

    Authors: Matthieu Hanf, Aurélia Stéphani, Célia Basurko, Mathieu Nacher and Bernard Carme
    Citation: Malaria Journal 2009 8:278
  23. A 20 year-old healthy female volunteer participated in a clinical Phase I and IIa safety and efficacy trial with candidate malaria vaccine Pf LSA-3-rec adjuvanted with aluminium hydroxide. Eleven weeks after the ...

    Authors: An-Emmie Nieman, Quirijn de Mast, Meta Roestenberg, Jorien Wiersma, Gheorghe Pop, Anton Stalenhoef, Pierre Druilhe, Robert Sauerwein and André van der Ven
    Citation: Malaria Journal 2009 8:277
  24. There is currently no standard way of defining malaria seasonality, resulting in a wide range of definitions reported in the literature. Malaria cases show seasonal peaks in most endemic settings, and the choi...

    Authors: Arantxa Roca-Feltrer, Joanna RM Armstrong Schellenberg, Lucy Smith and Ilona Carneiro
    Citation: Malaria Journal 2009 8:276
  25. Angola's malaria case-management policy recommends treatment with artemether-lumefantrine (AL). In 2006, AL implementation began in Huambo Province, which involved training health workers (HWs), supervision, d...

    Authors: Alexander K Rowe, Gabriel F Ponce de León, Jules Mihigo, Ana Carolina FS Santelli, Nathan P Miller and Pedro Van-Dúnem
    Citation: Malaria Journal 2009 8:275
  26. Health record-based observations from several parts of Africa indicate a major decline in malaria, but up-to-date information on parasite prevalence in West-Africa is sparse. This study aims to provide parasit...

    Authors: Judith Satoguina, Brigitte Walther, Christopher Drakeley, Davis Nwakanma, Eniyou C Oriero, Simon Correa, Patrick Corran, David J Conway and Michael Walther
    Citation: Malaria Journal 2009 8:274
  27. Seizures are common in children admitted with severe falciparum malaria and are associated with neuro-cognitive impairments. Prolonged febrile seizures are associated with hippocampal damage and impaired memor...

    Authors: Michael Kihara, Julie A Carter, Penny A Holding, Faraneh Vargha-Khadem, Rod C Scott, Richard Idro, Greg W Fegan, Michelle de Haan, Brian GR Neville and Charles RJC Newton
    Citation: Malaria Journal 2009 8:273
  28. Artemisinin combination therapy has become the standard of care for uncomplicated malaria in most of Africa. However, there is limited data on the safety and tolerability of these drugs, especially in young ch...

    Authors: Shereen Katrak, Anne Gasasira, Emmanuel Arinaitwe, Abel Kakuru, Humphrey Wanzira, Victor Bigira, Taylor G Sandison, Jaco Homsy, Jordan W Tappero, Moses R Kamya and Grant Dorsey
    Citation: Malaria Journal 2009 8:272
  29. The prozone effect (or high doses-hook phenomenon) consists of false-negative or false-low results in immunological tests, due to an excess of either antigens or antibodies. Although frequently cited as a caus...

    Authors: Philippe Gillet, Marcella Mori, Marjan Van Esbroeck, Jef Van den Ende and Jan Jacobs
    Citation: Malaria Journal 2009 8:271
  30. Recently, it has been assumed that resistance of Plasmodium to chloroquine increased malaria mortality. The study aimed to assess the impact of chemoresistance on mortality attributable to malaria in a rural a...

    Authors: Aline Munier, Aldiouma Diallo, Adama Marra, Michel Cot, Pascal Arduin, Ousmane Ndiaye, Balla Mbacké Mboup, Barnabé Gning and Jean-Philippe Chippaux
    Citation: Malaria Journal 2009 8:270
  31. The simian malaria parasite Plasmodium knowlesi is transmitted in the forests of Southeast Asia. Symptomatic zoonotic knowlesi malaria in humans is widespread in the region and is associated with a history of spe...

    Authors: Janet Cox-Singh
    Citation: Malaria Journal 2009 8:269
  32. The Anopheles gambiae and Anopheles funestus mosquito species complexes are the primary vectors of Plasmodium falciparum malaria in sub-Saharan Africa. To better understand the environmental factors influencing t...

    Authors: Louise A Kelly-Hope, Janet Hemingway and F Ellis McKenzie
    Citation: Malaria Journal 2009 8:268
  33. The introduction of artemesinin-based treatment for falciparum malaria has led to a shift away from symptom-based diagnosis. Diagnosis may be achieved by using rapid non-microscopic diagnostic tests (RDTs), of...

    Authors: Katherine M Bowers, David Bell, Peter L Chiodini, John Barnwell, Sandra Incardona, Seiha Yen, Jennifer Luchavez and Hilary Watt
    Citation: Malaria Journal 2009 8:267
  34. Effective and timely treatment is an essential aspect of malaria control, but remains a challenge in many parts of sub-Saharan Africa. The objective of this study was to describe young children's access to mal...

    Authors: Maike Tipke, Valérie R Louis, Maurice Yé, Manuela De Allegri, Claudia Beiersmann, Ali Sié, Olaf Mueller and Albrecht Jahn
    Citation: Malaria Journal 2009 8:266
  35. The diagnosis and treatment of malaria is often based on syndromic presentation (presumptive treatment) and microscopic examination of blood films. Treatment based on syndromic approach has been found to be co...

    Authors: Benjamin SC Uzochukwu, Eric N Obikeze, Obinna E Onwujekwe, Chima A Onoka and Ulla K Griffiths
    Citation: Malaria Journal 2009 8:265
  36. Many countries across sub-Saharan Africa are rapidly increasing insecticide-treated net (ITN) coverage to combat malaria, but systematic data on the use of those ITNs and the factors affecting this use are sca...

    Authors: Carol A Baume, Richard Reithinger and Sara Woldehanna
    Citation: Malaria Journal 2009 8:264
  37. MSP1 processing-inhibitory antibodies bind to epitopes on the 19 kDa C-terminal region of the Plasmodium falciparum merozoite surface protein 1 (MSP119), inhibiting erythrocyte invasion. Blocking antibodies also ...

    Authors: Christian MF Okafor, Chiaka I Anumudu, Yusuf O Omosun, Chairat Uthaipibull, Idowu Ayede, Henrietta O Awobode, Alex B Odaibo, Jean Langhorne, Anthony A Holder, Roseangela I Nwuba and Marita Troye-Blomberg
    Citation: Malaria Journal 2009 8:263
  38. The SD FK80 P.f/P.v Malaria Antigen Rapid Test (Standard Diagnostics, Korea) (FK80) is a three-band malaria rapid diagnostic test detecting Plasmodium falciparum histidine-rich protein-2 (HRP-2) and Plasmodium vi...

    Authors: Philippe Gillet, David PJ van Dijk, Emmanuel Bottieau, Lieselotte Cnops, Marjan Van Esbroeck and Jan Jacobs
    Citation: Malaria Journal 2009 8:262
  39. Facilitation of endogenous neuroprotective pathways, such as the erythropoietin (Epo) pathway, has been proposed as adjuvant treatment strategies in cerebral malaria. Whether different endogenous protein expre...

    Authors: Isabelle M Medana, Nicholas PJ Day, Tran Tinh Hien, Nicholas J White and Gareth DH Turner
    Citation: Malaria Journal 2009 8:261
  40. Malaria remains a major cause of morbidity and mortality among children under five years of age in Nigeria. Most of the early treatments for fever and malaria occur through self-medication with anti-malarials ...

    Authors: Theodora A Okeke and Benjamin SC Uzochukwu
    Citation: Malaria Journal 2009 8:260
  41. Anopheles albimanus is an important malaria vector in some areas throughout its distribution in the Caribbean and the Pacific regions of Colombia, covering three biogeographic zones of the neotropical region, Mar...

    Authors: Lina A Gutiérrez, Nelson J Naranjo, Astrid V Cienfuegos, Carlos E Muskus, Shirley Luckhart, Jan E Conn and Margarita M Correa
    Citation: Malaria Journal 2009 8:259
  42. HIV-1 infection affects malaria humeral immunity during pregnancy, but data for non-pregnant adults are lacking. This study reports the impact of HIV-1 infection and other variables on the level of malaria hum...

    Authors: Jean-Pierre Van Geertruyden, Erika Van Eijk, Francisca Yosaatmadja, Webster Kasongo, Modest Mulenga, Umberto D'Alessandro and Stephen Rogerson
    Citation: Malaria Journal 2009 8:258
  43. Although there are many methods available for measuring compliance, there is no formal gold standard. Different techniques used to measure compliance were compared among children treated by the anti-malarial a...

    Authors: Aurélia Souares, Patricia Moulin, Sophie Sarrassat, Marie-Paule Carlotti, Richard Lalou and Jean-Yves Le Hesran
    Citation: Malaria Journal 2009 8:257
  44. Detection of malaria pigment (or haemozoin; Hz)-containing leukocytes may have prognostic relevance in malaria; however, studies reported conflicting results, with microscopic counts suggestive of being inaccu...

    Authors: Thomas Hänscheid, Rosangela Frita, Matthias Längin, Peter G Kremsner and Martin P Grobusch
    Citation: Malaria Journal 2009 8:255
  45. As a result of increased support and the diligent application of new and conventional anti-malaria tools, significant reductions in malaria transmission are being accomplished. Historical and current evolution...

    Authors: Harold Townson
    Citation: Malaria Journal 2009 8(Suppl 2):S10

    This article is part of a Supplement: Volume 8 Supplement 2

  46. The success of the sterile insect technique (SIT) and other genetic strategies designed to eliminate large populations of insects relies on the efficient inundative releases of competitive, sterile males into ...

    Authors: Philippos A Papathanos, Hervé C Bossin, Mark Q Benedict, Flaminia Catteruccia, Colin A Malcolm, Luke Alphey and Andrea Crisanti
    Citation: Malaria Journal 2009 8(Suppl 2):S5

    This article is part of a Supplement: Volume 8 Supplement 2

  47. The global malaria situation, especially in Africa, and the problems frequently encountered in chemical control of vectors such as insecticide resistance, emphasize the urgency of research, development and imp...

    Authors: Badria B El Sayed, Colin A Malcolm, Ahmed Babiker, Elfatih M Malik, Mohammed AH El Tayeb, Nageeb S Saeed, Abdel Hameed D Nugud and Bart GJ Knols
    Citation: Malaria Journal 2009 8(Suppl 2):S3

    This article is part of a Supplement: Volume 8 Supplement 2

  48. The sterile insect technique (SIT) has been shown to be an effective and sustainable genetic approach to control populations of selected major pest insects, when part of area-wide integrated pest management (A...

    Authors: Alan S Robinson, Bart GJ Knols, Gabriella Voigt and Jorge Hendrichs
    Citation: Malaria Journal 2009 8(Suppl 2):S1

    This article is part of a Supplement: Volume 8 Supplement 2

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