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  1. Severe malarial anaemia is a major complication of malaria infection and is multi-factorial resulting from loss of circulating red blood cells (RBCs) from parasite replication, as well as immune-mediated mecha...

    Authors: Tracey J Lamb and Jean Langhorne
    Citation: Malaria Journal 2008 7:68
  2. Aggregated haemozoin crystals within malaria-infected erythrocytes confer susceptibility of parasitized cells to a magnetic field. Here the utility of this method for diagnosis of human malaria is evaluated in...

    Authors: Stephan Karl, Makindi David, Lee Moore, Brian T Grimberg, Pascal Michon, Ivo Mueller, Maciej Zborowski and Peter A Zimmerman
    Citation: Malaria Journal 2008 7:66
  3. The work described in this article forms part of a study to suppress a population of the malaria vector Anopheles arabiensis in Northern State, Sudan, with the Sterile Insect Technique. No data have previously be...

    Authors: Michelle EH Helinski, Mo'awia M Hassan, Waleed M El-Motasim, Colin A Malcolm, Bart GJ Knols and Badria El-Sayed
    Citation: Malaria Journal 2008 7:65
  4. Daily assessment of the percentage of erythrocytes that are infected ('percent-parasitaemia') across a time-course is a necessary step in many experimental studies of malaria, but represents a time-consuming a...

    Authors: Owen Proudfoot, Nathan Drew, Anja Scholzen, Sue Xiang and Magdalena Plebanski
    Citation: Malaria Journal 2008 7:62
  5. In Papua New Guinea (PNG), combination therapy with amodiaquine (AQ) or chloroquine (CQ) plus sulphadoxine-pyrimethamine (SP) was introduced as first-line treatment against uncomplicated malaria in 2000.

    Authors: Jutta Marfurt, Ivo Müller, Albert Sie, Olive Oa, John C Reeder, Thomas A Smith, Hans-Peter Beck and Blaise Genton
    Citation: Malaria Journal 2008 7:61
  6. Insecticide-treated bed nets (ITNs) range among the most effective measures of malaria prophylaxis, yet their implementation level in sub-Saharan Africa is still low. The goal of this study was to investigate ...

    Authors: Julia N Goesch, Norbert G Schwarz, Marie-Luise Decker, Sunny Oyakhirome, Lea B Borchert, Ulrich D Kombila, Marc Poetschke, Bertrand Lell, Saadou Issifou, Peter G Kremsner and Martin P Grobusch
    Citation: Malaria Journal 2008 7:60
  7. Entomological surveys are of great importance in decision-making processes regarding malaria control strategies because they help to identify associations between vector abundance both species-specific ecology...

    Authors: Eliningaya J Kweka, Watoky MM Nkya, Aneth M Mahande, Charles Assenga, Franklin W Mosha, Ester E Lyatuu, Charles P Massenga, Edwin M Nyale, Stephen B Mwakalinga and Asanterabi Lowassa
    Citation: Malaria Journal 2008 7:59
  8. Combination therapy has become a new paradigm in malaria treatment. Amodiaquine is a common partner drug in different malaria combination therapies used or investigated in sub-Saharan Africa, but data on its e...

    Authors: Germain Mandi, Frank P Mockenhaupt, Boubacar Coulibaly, Peter Meissner and Olaf Müller
    Citation: Malaria Journal 2008 7:58
  9. The treatment options for acute Plasmodium falciparum malaria are based on the clinician classifying the patient as uncomplicated or severe according to the clinical and parasitological findings. This process is ...

    Authors: Khin Maung Lwin, Elizabeth A Ashley, Stephane Proux, Kamolrat Silamut, François Nosten and Rose McGready
    Citation: Malaria Journal 2008 7:57
  10. International travel and migration have been related with an increase of imported malaria cases. There has been considerable immigration to Barcelona from low-income countries (LIC) in recent years. The object...

    Authors: Juan Pablo Millet, Patricia Garcia de Olalla, Paloma Carrillo-Santisteve, Joaquim Gascón, Begoña Treviño, José Muñoz, Jordi Gómez i Prat, Juan Cabezos, Anna González Cordón and Joan A Caylà
    Citation: Malaria Journal 2008 7:56
  11. In order to improve the monitoring of the antimalarial drug resistance in Madagascar, a new national network based on eight sentinel sites was set up. In 2006/2007, a multi-site randomized clinical trial was d...

    Authors: Didier Ménard, Arsène Ratsimbasoa, Milijaona Randrianarivelojosia, Léon-Paul Rabarijaona, Lucie Raharimalala, Olivier Domarle, Laurence Randrianasolo, Arthur Randriamanantena, Martial Jahevitra, Valérie Andriantsoanirina, Marie-Ange Rason, Rogelin Raherinjafy, Emma Rakotomalala, Luciano Tuseo and Andrianirina Raveloson
    Citation: Malaria Journal 2008 7:55
  12. Intermittent preventive (or presumptive) treatment of infants (IPTi), the administration of a curative anti-malarial dose to infants whether or not they are known to be infected, is being considered as a new s...

    Authors: Roly D Gosling, Azra C Ghani, Jaqueline L Deen, Lorenz von Seidlein, Brian M Greenwood and Daniel Chandramohan
    Citation: Malaria Journal 2008 7:54
  13. Malaria over-diagnosis in Africa is widespread and costly both financially and in terms of morbidity and mortality from missed diagnoses. An understanding of the reasons behind malaria over-diagnosis is urgent...

    Authors: Clare IR Chandler, Caroline Jones, Gloria Boniface, Kaseem Juma, Hugh Reyburn and Christopher JM Whitty
    Citation: Malaria Journal 2008 7:53
  14. A large focus of human infections with Plasmodium knowlesi, a simian parasite naturally found in long-tailed and pig-tailed macaques was discovered in the Kapit Division of Sarawak, Malaysian Borneo. A study was ...

    Authors: Cheong H Tan, Indra Vythilingam, Asmad Matusop, Seng T Chan and Balbir Singh
    Citation: Malaria Journal 2008 7:52
  15. Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum erythrocyte membrane protein 1 f...

    Authors: Francisca Yosaatmadja, Katherine T Andrews, Michael F Duffy, Graham V Brown, James G Beeson and Stephen J Rogerson
    Citation: Malaria Journal 2008 7:51
  16. In the rural areas of sub-Saharan Africa, the majority of young children affected by malaria have no access to formal health services. Home treatment through mothers of febrile children supported by mother gro...

    Authors: Bocar Kouyaté, Florent Somé, Albrecht Jahn, Boubacar Coulibaly, Jaran Eriksen, Rainer Sauerborn, Lars Gustafsson, Göran Tomson, Heiko Becher and Olaf Mueller
    Citation: Malaria Journal 2008 7:50
  17. In order to evaluate whether criteria for LLIN field performance (phase III) set by the WHO Pesticide Evaluation Scheme are met, first and second generations of one of these products, PermaNet®, a polyester net u...

    Authors: Albert Kilian, Wilson Byamukama, Olivier Pigeon, Francis Atieli, Stephan Duchon and Chi Phan
    Citation: Malaria Journal 2008 7:49
  18. Sulphadoxine-pyrimethamine has been abandoned as first- or second-line treatment by most African malaria endemic countries in favour of artemisinin-based combination treatments, but the drug is still used as i...

    Authors: Petra F Mens, Chantal van Overmeir, Maryline Bonnet, Jean-Claude Dujardin and Umberto d'Alessandro
    Citation: Malaria Journal 2008 7:48
  19. The transcriptional regulation of Plasmodium during its complex life cycle requires sequential activation and/or repression of different genetic programmes. MicroRNAs (miRNAs) are a highly conserved class of non-...

    Authors: Xiangyang Xue, Qingfeng Zhang, Yufu Huang, Le Feng and Weiqing Pan
    Citation: Malaria Journal 2008 7:47
  20. Segmental duplications (SD) have been found in genomes of various organisms, often accumulated at the ends of chromosomes. It has been assumed that the sequence homology in-between the SDs allow for ectopic in...

    Authors: Bobo W Mok, Ulf Ribacke, Ellen Sherwood and Mats Wahlgren
    Citation: Malaria Journal 2008 7:46
  21. Parasite concentration methods facilitate molecular, biochemical and immunological research on the erythrocytic stages of Plasmodium. In this paper, an adaptation of magnetic MACS® columns for the purification of...

    Authors: Clotilde Ribaut, Antoine Berry, Séverine Chevalley, Karine Reybier, Isabelle Morlais, Daniel Parzy, Françoise Nepveu, Françoise Benoit-Vical and Alexis Valentin
    Citation: Malaria Journal 2008 7:45
  22. To reduce the intolerable burden of malaria in pregnancy, the Ministry of Health in Uganda improved the antenatal care package by including a strong commitment to increase distribution of insecticide-treated n...

    Authors: Mpungu S Kiwuwa and Patrobas Mufubenga
    Citation: Malaria Journal 2008 7:44
  23. Studies were conducted between April 2004 and February 2006 to determine the blood-feeding pattern of Anopheles mosquitoes in Mwea Kenya.

    Authors: Simon M Muriu, Ephantus J Muturi, Josephat I Shililu, Charles M Mbogo, Joseph M Mwangangi, Benjamin G Jacob, Lucy W Irungu, Richard W Mukabana, John I Githure and Robert J Novak
    Citation: Malaria Journal 2008 7:43
  24. In Plasmodium falciparum-infected children, the relationships between blood cell histopathology, blood plasma components, development of immunocompetence and disease severity remain poorly understood. Blood from ...

    Authors: Virginia S Baker, Godwin E Imade, Norman B Molta, Pallavi Tawde, Sunday D Pam, Michael O Obadofin, Soloman A Sagay, Daniel Z Egah, Daniel Iya, Bangmboye B Afolabi, Murray Baker, Karen Ford, Robert Ford, Kenneth H Roux and Thomas CS Keller III
    Citation: Malaria Journal 2008 7:41
  25. Transmission of Plasmodium falciparum generally decreases with increasing elevation, in part because lower temperature slows the development of both parasites and mosquitoes. However, other aspects of the terrain...

    Authors: Justin M Cohen, Kacey C Ernst, Kim A Lindblade, John M Vulule, Chandy C John and Mark L Wilson
    Citation: Malaria Journal 2008 7:40
  26. Urban malaria is likely to become increasingly important as a consequence of the growing proportion of Africans living in cities. A novel sampling strategy was developed for urban areas to generate a sample si...

    Authors: Jose G Siri, Kim A Lindblade, Daniel H Rosen, Bernard Onyango, John M Vulule, Laurence Slutsker and Mark L Wilson
    Citation: Malaria Journal 2008 7:39
  27. Long-lasting insecticidal nets (LLINs) are advocated by WHO for protection against malaria. Of the three brands of LLINs currently approved by WHO, Olyset® is the only one currently granted full recommendation. W...

    Authors: Robert C Malima, Stephen M Magesa, Patrick K Tungu, Victor Mwingira, Frank S Magogo, Wema Sudi, Frank W Mosha, Christopher F Curtis, Caroline Maxwell and Mark Rowland
    Citation: Malaria Journal 2008 7:38
  28. Characterization of severe malaria cases on arrival to hospital may lead to early recognition and improved management. Minimum community based-incidence rates (MCBIRs) complement hospital data, describing the ...

    Authors: Quique Bassat, Caterina Guinovart, Betuel Sigaúque, Pedro Aide, Jahit Sacarlal, Tacilta Nhampossa, Azucena Bardají, Ariel Nhacolo, Eusébio Macete, Inácio Mandomando, John J Aponte, Clara Menéndez and Pedro L Alonso
    Citation: Malaria Journal 2008 7:37
  29. Malaria represents a huge burden for the health care services across Africa. Describing malaria attending health services contributes to quantify the burden and describe the epidemiology and clinical presentat...

    Authors: Caterina Guinovart, Quique Bassat, Betuel Sigaúque, Pedro Aide, Jahit Sacarlal, Tacilta Nhampossa, Azucena Bardají, Ariel Nhacolo, Eusébio Macete, Inácio Mandomando, John J Aponte, Clara Menéndez and Pedro L Alonso
    Citation: Malaria Journal 2008 7:36
  30. Four of five Plasmodium species infecting humans are present in Madagascar. Plasmodium vivax remains the second most prevalent species, but is understudied. No data is available on its susceptibility to sulphadox...

    Authors: Céline Barnadas, Magali Tichit, Christiane Bouchier, Arsène Ratsimbasoa, Laurence Randrianasolo, Rogelin Raherinjafy, Martial Jahevitra, Stéphane Picot and Didier Ménard
    Citation: Malaria Journal 2008 7:35
  31. Although sub-Saharan Africa (SSA) is rapidly urbanizing, the terms used to classify urban ecotypes are poorly defined in the context of malaria epidemiology. Lack of clear definitions may cause misclassificati...

    Authors: Jose G Siri, Kim A Lindblade, Daniel H Rosen, Bernard Onyango, John Vulule, Laurence Slutsker and Mark L Wilson
    Citation: Malaria Journal 2008 7:34
  32. It is estimated that over 70% of patients with suspected malaria in sub-Saharan Africa, diagnose and manage their illness at home without referral to a formal health clinic. Of those patients who do attend a f...

    Authors: Jen CC Hume, Guy Barnish, Tara Mangal, Luiz Armázio, Elizabeth Streat and Imelda Bates
    Citation: Malaria Journal 2008 7:33
  33. In Gabon, following the adoption of amodiaquine/artesunate combination (AQ/AS) as first-line treatment of malaria and of sulphadoxine/pyrimethamine (SP) for preventive intermittent treatment of pregnant women,...

    Authors: Basile Nsimba, Vincent Guiyedi, Modeste Mabika-Mamfoumbi, Jean Romain Mourou-Mbina, Edgard Ngoungou, Marielle Bouyou-Akotet, Romaric Loembet, Rémy Durand, Jacques Le Bras and Maryvonne Kombila
    Citation: Malaria Journal 2008 7:31
  34. Kenya recently changed its antimalarial drug policy to a specific artemisinin-based combination therapy (ACT), artemether-lumefantrine (AL). New national guidelines on the diagnosis, treatment and prevention w...

    Authors: Beatrice Wasunna, Dejan Zurovac, Catherine A Goodman and Robert W Snow
    Citation: Malaria Journal 2008 7:29
  35. In Central Vietnam, forest malaria remains difficult to control due to the complex interactions between human, vector and environmental factors.

    Authors: Ngo Duc Thang, Annette Erhart, Niko Speybroeck, Le Xuan Hung, Le Khanh Thuan, Cong Trinh Hung, Pham Van Ky, Marc Coosemans and Umberto D'Alessandro
    Citation: Malaria Journal 2008 7:28
  36. There is a widespread notion, based on limited information, that in areas of stable malaria transmission most pregnant women with Plasmodium falciparum infection are asymptomatic. This study aim to characterize t...

    Authors: Azucena Bardají, Betuel Sigauque, Laia Bruni, Cleofé Romagosa, Sergi Sanz, Samuel Mabunda, Inacio Mandomando, John Aponte, Esperança Sevene, Pedro L Alonso and Clara Menéndez
    Citation: Malaria Journal 2008 7:27
  37. Placental malaria (PM) is an important cause of maternal and foetal mortality in tropical areas, and severe sequelae and mortality are related to inflammation in the placenta. Diagnosis is difficult because PM...

    Authors: Edward R Kabyemela, Atis Muehlenbachs, Michal Fried, Jonathan D Kurtis, Theonest K Mutabingwa and Patrick E Duffy
    Citation: Malaria Journal 2008 7:26
  38. Following the recognition that morbidity and mortality due to malaria had dramatically increased in the last three decades, in 2002 the government of Zambia reviewed its efforts to prevent and treat malaria. C...

    Authors: Naawa Sipilanyambe, Jonathon L Simon, Pascalina Chanda, Peter Olumese, Robert W Snow and Davidson H Hamer
    Citation: Malaria Journal 2008 7:25
  39. Many Nigerian children with malaria are treated at home. Treatments are mostly incorrect, due to caregivers' poor knowledge of appropriate and correct dose of drugs. A comparative study was carried out in two ...

    Authors: Ikeoluwapo O Ajayi, Catherine O Falade, E Afolabi Bamgboye, Ayo MJ Oduola and Oladele O Kale
    Citation: Malaria Journal 2008 7:24
  40. The emergence of Plasmodium falciparum resistant to most currently used antimalarial drugs is the major problem in malaria control along the Thai-Myanmar and Thai-Cambodia borders. Although artemisinin-based comb...

    Authors: Rommanee Khositnithikul, Peerapan Tan-ariya and Mathirut Mungthin
    Citation: Malaria Journal 2008 7:23
  41. Malaria microscopy remains the reference standard for malaria diagnosis in clinical trials (drug and vaccine), new diagnostic evaluation, as well as in clinical care in much of the world today. It is known tha...

    Authors: Colin Ohrt, Wendy Prudhomme O'Meara, Shon Remich, Peter McEvoy, Bernhards Ogutu, Ramadan Mtalib and James Sande Odera
    Citation: Malaria Journal 2008 7:22
  42. Rapid diagnostic tests (RDTs) for malaria are increasingly being considered for routine use in Africa. However, many RDTs are available and selecting the ideal test for a particular setting is challenging. The...

    Authors: Yoel Lubell, Heidi Hopkins, Christopher JM Whitty, Sarah G Staedke and Anne Mills
    Citation: Malaria Journal 2008 7:21
  43. As the population of Africa rapidly urbanizes, large populations could be protected from malaria by controlling aquatic stages of mosquitoes if cost-effective and scalable implementation systems can be designed.

    Authors: Ulrike Fillinger, Khadija Kannady, George William, Michael J Vanek, Stefan Dongus, Dickson Nyika, Yvonne Geissbühler, Prosper P Chaki, Nico J Govella, Evan M Mathenge, Burton H Singer, Hassan Mshinda, Steven W Lindsay, Marcel Tanner, Deo Mtasiwa, Marcia C de Castro…
    Citation: Malaria Journal 2008 7:20

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