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  1. Severe anaemia (SA), intravascular haemolysis (IVH) and respiratory distress (RD) are severe forms of Plasmodium falciparum malaria, with RD reported to be of prognostic importance in African children with malari...

    Authors: Gideon K Helegbe, Bamenla Q Goka, Joergen AL Kurtzhals, Michael M Addae, Edwin Ollaga, John KA Tetteh, Daniel Dodoo, Michael F Ofori, George Obeng-Adjei, Kenji Hirayama, Gordon A Awandare and Bartholomew D Akanmori
    Citation: Malaria Journal 2007 6:165
  2. The antimalarial drug atovaquone specifically targets Plasmodium falciparum cytochrome b (Pfcytb), a mitochondrial gene with uniparental inheritance. Cases of resistance to atovaquone associated with mutant Pfcyt...

    Authors: Marie-Thérèse Ekala, Nimol Khim, Eric Legrand, Milijaona Randrianarivelojosia, Ronan Jambou, Thierry Fandeur, Didier Menard, Serge-Brice Assi, Marie-Claire Henry, Christophe Rogier, Christiane Bouchier and Odile Mercereau-Puijalon
    Citation: Malaria Journal 2007 6:164
  3. Intermittent preventive antimalarial treatment in infants (IPTi) is currently evaluated as a malaria control strategy. Among the factors influencing the extent of protection that is provided by IPTi are the tr...

    Authors: Robin Kobbe, Samuel Adjei, Christina Kreuzberg, Benno Kreuels, Benedicta Thompson, Peter A Thompson, Florian Marks, Wibke Busch, Meral Tosun, Nadine Schreiber, Ernest Opoku, Ohene Adjei, Christian G Meyer and Juergen May
    Citation: Malaria Journal 2007 6:163
  4. Malaria is a significant public health problem in Tanzania. Approximately 16 million malaria cases are reported every year and 100,000 to 125,000 deaths occur. Although most of Tanzania is endemic to malaria, ...

    Authors: Anne E Jones, Ulrika Uddenfeldt Wort, Andrew P Morse, Ian M Hastings and Alexandre S Gagnon
    Citation: Malaria Journal 2007 6:162
  5. The development of acquired protective immunity to Plasmodium falciparum infection in young African children is considered in the context of three current strategies for malaria prevention: insecticide-impregnate...

    Authors: Colin J Sutherland, Christopher J Drakeley and David Schellenberg
    Citation: Malaria Journal 2007 6:161
  6. Malaria in pregnancy is one of the major causes of maternal morbidity and adverse birth outcomes. In high transmission areas, its prevention has recently changed, moving from a weekly or bimonthly chemoprophyl...

    Authors: Valérie Briand, Gilles Cottrell, Achille Massougbodji and Michel Cot
    Citation: Malaria Journal 2007 6:160
  7. The emergence of Anopheles populations capable of withstanding lethal doses of insecticides has weakened the efficacy of most insecticide based strategies of vector control and, has highlighted the need for furth...

    Authors: Rousseau F Djouaka, Adekunle A Bakare, Honore S Bankole, Julien MC Doannio, Ousmane N Coulibaly, Hortense Kossou, Manuele Tamo, Harcourt I Basene, OK Popoola and Martin C Akogbeto
    Citation: Malaria Journal 2007 6:159
  8. Prevention of malaria epidemics is a priority for African countries. The 2000 malaria epidemic in Burundi prompted the government to implement measures for preventing future outbreaks. Case management with art...

    Authors: Natacha Protopopoff, Wim Van Bortel, Tanguy Marcotty, Michel Van Herp, Peter Maes, Dismas Baza, Umberto D'Alessandro and Marc Coosemans
    Citation: Malaria Journal 2007 6:158
  9. There have been reported cases of host-switching in avian and lizard species of Plasmodium (Apicomplexa, Haemosporidia), as well as in those infecting different primate species. However, no evidence has previousl...

    Authors: Linda Duval, Vincent Robert, Gabor Csorba, Alexandre Hassanin, Milijaona Randrianarivelojosia, Joe Walston, Thy Nhim, Steve M Goodman and Frédéric Ariey
    Citation: Malaria Journal 2007 6:157
  10. The susceptibility of microbes such as Plasmodium falciparum to drugs is measured in vitro as the concentration of the drug achieving 50% of maximum effect (IC50); values from a population are summarized as geome...

    Authors: Michel Vaillant and Piero Olliaro
    Citation: Malaria Journal 2007 6:156
  11. The Anopheles gambiae sensu lato species complex comprises seven sibling species of mosquitoes that are morphologically indistinguishable. Rapid identification of the two main species which vector malaria, Anophe...

    Authors: Chris Bass, Martin S Williamson, Craig S Wilding, Martin J Donnelly and Linda M Field
    Citation: Malaria Journal 2007 6:155
  12. The Plasmodium falciparum apical membrane antigen 1 (AMA1) is a leading malaria vaccine candidate antigen. The complete AMA1 protein is comprised of three domains where domain I exhibits high sequence polymorphis...

    Authors: Sheena Garg, Mohammad T Alam, Manoj K Das, Vas Dev, Ashwani Kumar, Aditya P Dash and Yagya D Sharma
    Citation: Malaria Journal 2007 6:154
  13. In malaria endemic areas children may recover from malaria after chemotherapy in spite of harbouring genotypically drug-resistant Plasmodium falciparum. This phenomenon suggests that there is a synergy between dr...

    Authors: Anders Enevold, Watoky MMM Nkya, Michael Theisen, Lasse S Vestergaard, Anja TR Jensen, Trine Staalsoe, Thor G Theander, Ib C Bygbjerg and Michael Alifrangis
    Citation: Malaria Journal 2007 6:153
  14. Quinine injection is the reference treatment for malaria when oral administration is impossible. Quinine can also be administered by the intra-rectal route and, over the last ten years, a series of studies hav...

    Authors: Jean Louis A Ndiaye, Roger C Tine, Babacar Faye, El Hadj Lamine Dieye, Pape Amadou Diack, Valérie Lameyre, Oumar Gaye and Husseyn Dembel Sow
    Citation: Malaria Journal 2007 6:152
  15. Four blood collection and transfer devices commonly used for malaria rapid diagnostic tests (RDTs) were assessed for their consistency, accuracy and ease of use in the hands of laboratory technicians and villa...

    Authors: Jennifer Luchavez, Ma Eichelle Lintag, Mary Coll-Black, Fred Baik and David Bell
    Citation: Malaria Journal 2007 6:149
  16. This work was carried out to assess the patterns and prevalence of resistance to chloroquine (CQ) and sulphadoxine-pyrimethamine (SP) in Iran.

    Authors: Sedigheh Zakeri, Mandana Afsharpad, Ahmad Raeisi and Navid Dinparast Djadid
    Citation: Malaria Journal 2007 6:148
  17. Plasmodium falciparum can cause a diffuse encephalopathy known as cerebral malaria (CM), a major contributor to malaria associated mortality. Despite treatment, mortality due to CM can be as high as 30% while 10%...

    Authors: Henry B Armah, Nana O Wilson, Bismark Y Sarfo, Michael D Powell, Vincent C Bond, Winston Anderson, Andrew A Adjei, Richard K Gyasi, Yao Tettey, Edwin K Wiredu, Jon Eric Tongren, Venkatachalam Udhayakumar and Jonathan K Stiles
    Citation: Malaria Journal 2007 6:147
  18. Tanzania switched the antimalarial first line to sulphadoxine-pyrimethamine (SP) in 2001 from ineffective chloroquine (CQ). By 2003 higher levels of SP resistance were recorded, prompting an urgent need for re...

    Authors: Abdunoor M Kabanywanyi, Alex Mwita, Deborah Sumari, Renata Mandike, Kefas Mugittu and Salim Abdulla
    Citation: Malaria Journal 2007 6:146
  19. Formal checks of participant understanding are now widely recommended to improve informed consent processes. However, the views of the participants these assessments are designed to protect are rarely consider...

    Authors: Sassy Molyneux, Caroline Gikonyo, Vicki Marsh and Philip Bejon
    Citation: Malaria Journal 2007 6:145
  20. Intermittent preventive treatment in pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) has been adopted as policy by many countries in sub-Saharan Africa. However, data on the post-implementation effectivene...

    Authors: Lena Hommerich, Christa von Oertzen, George Bedu-Addo, Ville Holmberg, Patrick A Acquah, Teunis A Eggelte, Ulrich Bienzle and Frank P Mockenhaupt
    Citation: Malaria Journal 2007 6:144
  21. Malaria and HIV are common causes of mortality in sub-Saharan Africa. The effect of HIV infection on morbidity and mortality in children with severe malarial anaemia was assessed.

    Authors: Samuel Malamba, Wolfgang Hladik, Arthur Reingold, Flora Banage, Willi McFarland, George Rutherford, Derrick Mimbe, Esau Nzaro, Robert Downing and Jonathan Mermin
    Citation: Malaria Journal 2007 6:143
  22. Indoor residual spraying (IRS) has again become popular for malaria control in Africa. This combined with the affirmation by WHO that DDT is appropriate for use in the absence of longer lasting insecticide for...

    Authors: Sonia LR Casimiro, Janet Hemingway, Brian L Sharp and Michael Coleman
    Citation: Malaria Journal 2007 6:142
  23. Malaria transmission in Equatorial Guinea and its space-time variability has been widely studied, but there is not much information about the transmission of malaria on the small island of Annobon. In 2004, tw...

    Authors: Jorge Cano, Pedro Berzosa, Aida de Lucio, Miguel Angel Descalzo, Leonardo Bobuakasi, Sisinio Nzambo, Melchor Ondo, Jesus N Buatiche, Gloria Nseng and Agustin Benito
    Citation: Malaria Journal 2007 6:141
  24. Malaria diagnosis is vital to efficient control programmes and the recent advent of malaria rapid diagnostic tests (RDTs) provides a reliable and simple diagnostic method. However a characterization of the eff...

    Authors: Arthur M Talman, Linda Duval, Eric Legrand, Véronique Hubert, Seiha Yen, David Bell, Jacques Le Bras, Frédéric Ariey and Sandrine Houze
    Citation: Malaria Journal 2007 6:140
  25. The susceptibility of anopheline mosquito species to Plasmodium infection is known to be variable with some mosquitoes more permissive to infection than others. Little work, however, has been carried out investig...

    Authors: Jennifer CC Hume, Mark Tunnicliff, Lisa C Ranford-Cartwright and Karen P Day
    Citation: Malaria Journal 2007 6:139
  26. Several reports have suggested that raised intracranial pressure (ICP) is a major contributor to death among children with cerebral malaria. Mannitol, an osmotic diuretic, effectively lowers ICP and is used to...

    Authors: Beatrice Namutangula, Grace Ndeezi, Justus S Byarugaba and James K Tumwine
    Citation: Malaria Journal 2007 6:138
  27. Patterns of genetic structure among mosquito vector populations in islands have received particular attention as these are considered potentially suitable sites for experimental trials on transgenic-based mala...

    Authors: Marta Moreno, Patricia Salgueiro, José Luis Vicente, Jorge Cano, Pedro J Berzosa, Aida de Lucio, Frederic Simard, Adalgisa Caccone, Virgilio E Do Rosario, João Pinto and Agustín Benito
    Citation: Malaria Journal 2007 6:137
  28. The present study has evaluated the immunogenicity of single or multiple Plasmodium falciparum (Pf) antigens administered in a DNA prime/poxvirus boost regimen with or without the poloxamer CRL1005 in rhesus monk...

    Authors: George Jiang, Yupin Charoenvit, Alberto Moreno, Maria F Baraceros, Glenna Banania, Nancy Richie, Steve Abot, Harini Ganeshan, Victoria Fallarme, Noelle B Patterson, Andrew Geall, Walter R Weiss, Elizabeth Strobert, Ivette Caro-Aquilar, David E Lanar, Allan Saul…
    Citation: Malaria Journal 2007 6:135
  29. Home-based management of malaria (HMM) is promoted as a major strategy to improve prompt delivery of effective malaria treatment in Africa. HMM involves presumptively treating febrile children with pre-package...

    Authors: Heidi Hopkins, Ambrose Talisuna, Christopher JM Whitty and Sarah G Staedke
    Citation: Malaria Journal 2007 6:134
  30. The malaria vector Anopheles gambiae is polymorphic for chromosomal inversions on the right arm of chromosome 2 that segregate nonrandomly between assortatively mating populations in West Africa. One such inversi...

    Authors: Mamadou B Coulibaly, Marco Pombi, Beniamino Caputo, Davis Nwakanma, Musa Jawara, Lassana Konate, Ibrahima Dia, Abdrahamane Fofana, Marcia Kern, Frédéric Simard, David J Conway, Vincenzo Petrarca, Alessandra della Torre, Sékou Traoré and Nora J Besansky
    Citation: Malaria Journal 2007 6:133
  31. Intermittent preventive treatment (IPTi) with sulphadoxine-pyrimethamine (SP) in infants resulted in different estimates of clinical malaria protection in two trials that used the same protocol in Ifakara, Tan...

    Authors: Clara Menendez, David Schellenberg, Eusebio Macete, Pedro Aide, Elizeus Kahigwa, Sergi Sanz, John J Aponte, Jahit Sacarlal, Hassan Mshinda, Marcel Tanner and Pedro L Alonso
    Citation: Malaria Journal 2007 6:132
  32. The Plasmodium falciparum parasite rate (PfPR) is a commonly reported index of malaria transmission intensity. PfPR rises after birth to a plateau before declining in older children and adults. Studies of populat...

    Authors: David L Smith, Carlos A Guerra, Robert W Snow and Simon I Hay
    Citation: Malaria Journal 2007 6:131
  33. The objective of this work was to develop a model to predict malaria incidence in an area of unstable transmission by studying the association between environmental variables and disease dynamics.

    Authors: Alberto Gomez-Elipe, Angel Otero, Michel van Herp and Armando Aguirre-Jaime
    Citation: Malaria Journal 2007 6:129
  34. Although malaria is one of the most important causes of death in Ethiopia, measuring the magnitude of malaria-attributed deaths at community level poses a considerable difficulty. Nevertheless, despite its low...

    Authors: Wakgari Deressa, Mesganaw Fantahun and Ahmed Ali
    Citation: Malaria Journal 2007 6:128
  35. The Atlantic rainforest ecosystem, where bromeliads are abundant, provides an excellent environment for Kerteszia species, because these anophelines use the axils of those plants as larval habitat. Anopheles (K.)...

    Authors: Mauro Toledo Marrelli, Rosely S Malafronte, Maria AM Sallum and Delsio Natal
    Citation: Malaria Journal 2007 6:127
  36. Successful malaria vector control depends on understanding behavioural interactions between mosquitoes and humans, which are highly setting-specific and may have characteristic features in urban environments. ...

    Authors: Yvonne Geissbühler, Prosper Chaki, Basiliana Emidi, Nicodemus J Govella, Rudolf Shirima, Valeliana Mayagaya, Deo Mtasiwa, Hassan Mshinda, Ulrike Fillinger, Steven W Lindsay, Khadija Kannady, Marcia Caldas de Castro, Marcel Tanner and Gerry F Killeen
    Citation: Malaria Journal 2007 6:126
  37. This paper reviews recent trends in the production, supply and price of the active ingredients as well as finished ACT products. Production and cost data provided in this paper are based on an ongoing project ...

    Authors: Jean-Marie Kindermans, Jacques Pilloy, Piero Olliaro and Melba Gomes
    Citation: Malaria Journal 2007 6:125
  38. Accurate diagnosis of Plasmodium spp. is essential for the rational treatment of malaria. Despite its many disadvantages, microscopic examination of blood smears remains the current "gold standard" for malaria de...

    Authors: Prapaporn Boonma, Peter R Christensen, Rossarin Suwanarusk, Ric N Price, Bruce Russell and Usa Lek-Uthai
    Citation: Malaria Journal 2007 6:124
  39. Despite a long history of attempts to model malaria epidemiology, the over-riding conclusion is that a detailed understanding of host-parasite interactions leading to immunity is required. It is still not know...

    Authors: Richard E Paul, Sarah Bonnet, Christian Boudin, Timoleon Tchuinkam and Vincent Robert
    Citation: Malaria Journal 2007 6:123
  40. A World Antimalarial Resistance Network (WARN) database has the potential to improve the treatment of malaria, through informing current drug selection and use and providing a prompt warning of when treatment ...

    Authors: Karen I Barnes, Niklas Lindegardh, Olumide Ogundahunsi, Piero Olliaro, Christopher V Plowe, Milijaona Randrianarivelojosia, Grace O Gbotosho, William M Watkins, Carol H Sibley and Nicholas J White
    Citation: Malaria Journal 2007 6:122
  41. Molecular markers for drug resistant malaria represent public health tools of great but mostly unrealized potential value. A key reason for the failure of molecular resistance markers to live up to their poten...

    Authors: Christopher V Plowe, Cally Roper, John W Barnwell, Christian T Happi, Hema H Joshi, Wilfred Mbacham, Steven R Meshnick, Kefas Mugittu, Inbarani Naidoo, Ric N Price, Robert W Shafer, Carol H Sibley, Colin J Sutherland, Peter A Zimmerman and Philip J Rosenthal
    Citation: Malaria Journal 2007 6:121
  42. Intrinsic resistance of Plasmodium falciparum is clearly a major determinant of the clinical failure of antimalarial drugs. However, complex interactions between the host, the parasite and the drug obscure the ab...

    Authors: David J Bacon, Ronan Jambou, Thierry Fandeur, Jacques Le Bras, Chansuda Wongsrichanalai, Mark M Fukuda, Pascal Ringwald, Carol Hopkins Sibley and Dennis E Kyle
    Citation: Malaria Journal 2007 6:120
  43. The proliferation of antimalarial drug trials in the last ten years provides the opportunity to launch a concerted global surveillance effort to monitor antimalarial drug efficacy. The diversity of clinical st...

    Authors: Ric N Price, Grant Dorsey, Elizabeth A Ashley, Karen I Barnes, J Kevin Baird, Umberto d'Alessandro, Philippe J Guerin, Miriam K Laufer, Inbarani Naidoo, François Nosten, Piero Olliaro, Christopher V Plowe, Pascal Ringwald, Carol H Sibley, Kasia Stepniewska and Nicholas J White
    Citation: Malaria Journal 2007 6:119
  44. In sub-Saharan areas, malaria transmission was mainly ensured by Anopheles. gambiae s.l. and Anopheles. funestus vectors. The immune response status to Plasmodium falciparum was evaluated in children living in tw...

    Authors: Jean Biram Sarr, Franck Remoue, Badara Samb, Ibrahima Dia, Sohibou Guindo, Cheikh Sow, Sophie Maiga, Seydou Tine, Cheikh Thiam, Anne-Marie Schacht, François Simondon, Lassana Konate and Gilles Riveau
    Citation: Malaria Journal 2007 6:117
  45. The Nias district of the North Sumatra Province of Indonesia has long been known to be endemic for malaria. Following the economic crisis at the end of 1998 and the subsequent tsunami and earthquake, in Decemb...

    Authors: Din Syafruddin, Puji BS Asih, Isra Wahid, Rita M Dewi, Sekar Tuti, Idaman Laowo, Waozidohu Hulu, Pardamean Zendrato, Ferdinand Laihad and Anuraj H Shankar
    Citation: Malaria Journal 2007 6:116

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