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  1. Anopheles gambiae is the main vector of Plasmodium falciparum in Africa. The mosquito midgut constitutes a barrier that the parasite must cross if it is to develop and be transmitted. Despite the central role of ...

    Authors: GI Prévot, C Laurent-Winter, F Rodhain and C Bourgouin
    Citation: Malaria Journal 2003 2:1
  2. The development and implementation of innovative vector control strategies for malaria control in Africa requires in-depth ecological studies in contained semi-field environments. This particularly applies to ...

    Authors: Bart GJ Knols, Basilio N Njiru, Evan M Mathenge, Wolfgang R Mukabana, John C Beier and Gerry F Killeen
    Citation: Malaria Journal 2002 1:19
  3. Many studies have suggested that variability in the attractiveness of humans to host-seeking mosquitoes is caused by differences in the make-up of body emanations, and olfactory signals in particular. Most inv...

    Authors: Wolfgang R Mukabana, Willem Takken, Richard Coe and Bart GJ Knols
    Citation: Malaria Journal 2002 1:17
  4. Malaria in pregnancy is characterised by the sequestration of Plasmodium falciparum-infected erythrocytes in placental intervillous spaces. Placental parasites express a specific phenotype, which allows them to c...

    Authors: Nadine Fievet, Germaine Tami, Bertrand Maubert, Marlène Moussa, Ian K Shaw, Michel Cot, Anthony A Holder, Gérard Chaouat and Philippe Deloron
    Citation: Malaria Journal 2002 1:16
  5. Insecticide-treated materials (ITMs) are effective in substantially reducing the burden of malaria and other vector-borne diseases; but how can high coverage rates of ITMs be achieved and maintained? In south ...

    Authors: Axel Kroeger, Ana Aviñna, José Ordoñnez-Gonzalez and Celia Escandon
    Citation: Malaria Journal 2002 1:15
  6. Sequential analysis enables repeated statistical analyses to be performed throughout a trial recruitment period, while maintaining a pre-specified power and type I error. Thus the trial can be stopped as soon ...

    Authors: Stéphane Ranque, Sékéné Badiaga, Jean Delmont and Philippe Brouqui
    Citation: Malaria Journal 2002 1:13
  7. The increasing levels of Plasmodium falciparum resistance to chloroquine (CQ) in Thailand have led to the use of alternative antimalarials, which are at present also becoming ineffective. In this context, any str...

    Authors: Dinora Lopes, Kanchana Rungsihirunrat, Fátima Nogueira, Aree Seugorn, José Pedro Gil, Virgilio E do Rosário and Pedro Cravo
    Citation: Malaria Journal 2002 1:12
  8. Results from numerous studies point convincingly to correlations between mutations at selected genes and phenotypic resistance to antimalarials in Plasmodium falciparum isolates. In order to move molecular assays...

    Authors: Tomas Jelinek, Gabriele Peyerl-Hoffmann, Nikolai Mühlberger, Ole Wichmann, Michael Wilhelm, Nadja Schmider, Martin P Grobusch, Frank von Sonnenburg, Joaquim Gascon, Hermann Laferl, Christoph Hatz, Michael Alifrangis, Gerd Burchard, Paul McWhinney, Marco Schulze, Herwig Kollaritsch…
    Citation: Malaria Journal 2002 1:11
  9. Plasmodium-refractory mosquitoes are being rapidly developed for malaria control but will only succeed if they can successfully compete for mates when released into the wild. Pre-copulatory behavioural traits mai...

    Authors: FM Okanda, A Dao, BN Njiru, J Arija, HA Akelo, Y Touré, A Odulaja, JC Beier, JI Githure, G Yan, LC Gouagna, BGJ Knols and GF Killeen
    Citation: Malaria Journal 2002 1:10
  10. Much communicable disease control research has had little impact on local control programme policy and practice for want of an operational component. The operational research model – the systematic search for ...

    Authors: David N Durrheim, Richard Speare and Anthony D Harries
    Citation: Malaria Journal 2002 1:9
  11. Based on sensitivity analysis of the MacDonald-Ross model, it has long been argued that the best way to reduce malaria transmission is to target adult female mosquitoes with insecticides that can reduce the lo...

    Authors: Gerry F Killeen, Ulrike Fillinger and Bart GJ Knols
    Citation: Malaria Journal 2002 1:8
  12. Plasmodium falciparum erythrocyte membrane protein-1, a variant antigen of the malaria parasite, is potentially a target for the immune response. It would be important to determine whether there are CD4 T cells t...

    Authors: Latifu A Sanni, Catherine EM Allsopp, Lieke Reubsaet, Ambaliou Sanni, Chris Newbold, Virander S Chauhan and Jean Langhorne
    Citation: Malaria Journal 2002 1:7
  13. In host erythrocytes, the malaria parasite must contend with ion and drug transport across three membranes; its own plasma membrane, the parasitophorous membrane and the host plasma membrane. Isolation of pure...

    Authors: Laurence M Elandalloussi and Pete J Smith
    Citation: Malaria Journal 2002 1:6
  14. Reversible protein phosphorylation is relatively unexplored in the intracellular protozoa of the Apicomplexa family that includes the genus Plasmodium, to which belong the causative agents of malaria. Members of ...

    Authors: Rajinder Kumar, Brian Adams, Anja Oldenburg, Alla Musiyenko and Sailen Barik
    Citation: Malaria Journal 2002 1:5
  15. We report the first in vitro and genetic confirmation of Malarone® (GlaxoSmithKline; atovaquone and proguanil hydrochloride) resistance in Plasmodium falciparum acquired in Africa. On presenting with malaria two ...

    Authors: Quinton L Fivelman, Geoffrey A Butcher, Ipemida S Adagu, David C Warhurst and Geoffrey Pasvol
    Citation: Malaria Journal 2002 1:1

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