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  1. The enantiomers of the 8-aminoquinoline anti-malarial primaquine have different pharmacological properties. Development of an analytical method for simultaneous quantification of the enantiomers of primaquine ...

    Authors: Warunee Hanpithakpong, Nicholas P. J. Day, Nicholas J. White and Joel Tarning
    Citation: Malaria Journal 2022 21:169
  2. It is often assumed that the population dynamics of the malaria vector Anopheles funestus, its role in malaria transmission and the way it responds to interventions are similar to the more elaborately characteriz...

    Authors: Halfan S. Ngowo, Fredros O. Okumu, Emmanuel E. Hape, Issa H. Mshani, Heather M. Ferguson and Jason Matthiopoulos
    Citation: Malaria Journal 2022 21:161
  3. Malaria control relies heavily on the use of anti-malarial drugs and insecticides against malaria parasites and mosquito vectors. Drug and insecticide resistance threatens the effectiveness of conventional mal...

    Authors: Charles Mulamba, Chris Williams, Katharina Kreppel, Jean Bosco Ouedraogo and Ally I. Olotu
    Citation: Malaria Journal 2022 21:159
  4. The most important malaria vectors in sub-Saharan Africa are Anopheles gambiae, Anopheles arabiensis, Anopheles funestus, and Anopheles coluzzii. Of these, An. funestus presently dominates in many settings in eas...

    Authors: Najat F. Kahamba, Marceline Finda, Halfan S. Ngowo, Betwel J. Msugupakulya, Francesco Baldini, Lizette L. Koekemoer, Heather M. Ferguson and Fredros O. Okumu
    Citation: Malaria Journal 2022 21:158
  5. In Brazil, malaria is caused mainly by the Plasmodium vivax and Plasmodium falciparum species. Its transmission occurs in endemic and non-endemic areas. Malaria geography in Brazil has retracted and is now concen...

    Authors: Klauss Kleydmann Sabino Garcia, Amanda Amaral Abrahão, Ana Flávia de Morais Oliveira, Karina Medeiros de Deus Henriques, Anielle de Pina-Costa, André Machado Siqueira and Walter Massa Ramalho
    Citation: Malaria Journal 2022 21:157
  6. Malaria case management relies on World Health Organization (WHO)-recommended artemisinin-based combination therapy (ACT), and a continuous understanding of local community knowledge, attitudes, and practices ...

    Authors: Jean Moise Tanga Kaboré, Mohamadou Siribié, Denise Hien, Issiaka Soulama, Nouhoun Barry, Yacouba Nombré, Frederic Dianda, Adama Baguiya, Alfred Bewendtaoré Tiono, Christian Burri, André-Marie Tchouatieu and Sodiomon Bienvenu Sirima
    Citation: Malaria Journal 2022 21:155
  7. Iron deficiency (ID) is common in malaria-endemic settings. Intermittent preventative treatment of malaria in pregnancy (IPTp) and iron supplementation are core components of antenatal care in endemic regions ...

    Authors: Holger W. Unger, Andie Bleicher, Maria Ome-Kaius, Elizabeth H. Aitken and Stephen J. Rogerson
    Citation: Malaria Journal 2022 21:153
  8. Building on an exercise that identified potential harms from simulated investigational releases of a population suppression gene drive for malaria vector control, a series of online workshops identified nine r...

    Authors: John B. Connolly, John D. Mumford, Debora C. M. Glandorf, Sarah Hartley, Owen T. Lewis, Sam Weiss Evans, Geoff Turner, Camilla Beech, Naima Sykes, Mamadou B. Coulibaly, Jörg Romeis, John L. Teem, Willy Tonui, Brian Lovett, Aditi Mankad, Abraham Mnzava…
    Citation: Malaria Journal 2022 21:152
  9. Targeting the asymptomatic liver stage of Plasmodium infection through chemoprevention could become a key intervention to reduce malaria-associated incidence and mortality.

    Authors: Akash Khandelwal, Francisca Arez, Paula M. Alves, Lassina Badolo, Catarina Brito, Christoph Fischli, Diana Fontinha, Claude Oeuvray, Miguel Prudêncio, Matthias Rottmann, Justin Wilkins, Özkan Yalkinoglu, Wilhelmina M. Bagchus and Thomas Spangenberg
    Citation: Malaria Journal 2022 21:151
  10. Malaria is a potentially fatal disease spread by the bites of Plasmodium-infected Anopheles mosquitoes. Despite long-term efforts to control malaria in Rwanda, malaria incidence increased from 48 to 403 cases/100...

    Authors: Ornella Masimbi, Janna M. Schurer, Ellen Rafferty, Jean D’ Amour Ndahimana and J. Hellen Amuguni
    Citation: Malaria Journal 2022 21:150
  11. The COVID-19 pandemic and its collateral damage severely impact health systems globally and risk to worsen the malaria situation in endemic countries. Malaria is a leading cause of morbidity and mortality in G...

    Authors: Anna-Katharina Heuschen, Alhassan Abdul-Mumin, Martin Adokiya, Guangyu Lu, Albrecht Jahn, Oliver Razum, Volker Winkler and Olaf Müller
    Citation: Malaria Journal 2022 21:149
  12. Species of Plasmodium (Haemosporida, Plasmodiidae) are remarkably diverse haemoparasites. Information on genetic diversity of avian malaria pathogens has been accumulating rapidly, however exo-erythrocytic develo...

    Authors: Helene Pendl, Carolina Hernández-Lara, Jakub Kubacki, Nicole Borel, Sarah Albini and Gediminas Valkiūnas
    Citation: Malaria Journal 2022 21:148
  13. In 2019, the RTS,S/AS01E malaria vaccine was introduced on a pilot basis in six regions of Ghana by the Ministry of Health/Ghana Health Service as part of the WHO-coordinated Malaria Vaccine Implementation Progra...

    Authors: Jane Grant, Thomas Gyan, Francis Agbokey, Jayne Webster, Brian Greenwood and Kwaku Poku Asante
    Citation: Malaria Journal 2022 21:147
  14. “Receptivity” to malaria is a construct developed during the Global Malaria Eradication Programme (GMEP) era. It has been defined in varied ways and no consistent, quantitative definition has emerged over the ...

    Authors: Joshua O. Yukich, Kim Lindblade and Jan Kolaczinski
    Citation: Malaria Journal 2022 21:145
  15. Over a third of the world’s population is at risk of Plasmodium vivax-induced malaria. The unique aspect of the parasite’s biology and interactions with the human host make it harder to control and eliminate the ...

    Authors: Natália S. Ferreira, Jéssica Lorena S. Mathias, Sérgio Roberto L. Albuquerque, Anne Cristine G. Almeida, Ana C. Dantas, Fernanda C. Anselmo, Emerson S. Lima, Marcus Vinicius G. Lacerda, Paulo A. Nogueira, Rajendranath Ramasawmy, Marilda S. Gonçalves and José P. Moura Neto
    Citation: Malaria Journal 2022 21:144
  16. In 2014, the Burkina Faso government launched the Seasonal Malaria Chemoprevention (SMC) programme. Expected benefit was a 75% reduction of all malaria episodes and a 75% drop of severe malaria episodes. This ...

    Authors: Fati Kirakoya-Samadoulougou, Vincent De Brouwere, Arnold Fottsoh Fokam, Mady Ouédraogo and Yazoumé Yé
    Citation: Malaria Journal 2022 21:143
  17. While human cases of Plasmodium knowlesi are now regularly recognized in Southeast Asia, infections with other simian malaria species, such as Plasmodium cynomolgi, are still rare. There has been a handful of cli...

    Authors: Piyaporn Sai-ngam, Kingkan Pidtana, Preeyaporn Suida, Kamonporn Poramathikul, Paphavee Lertsethtakarn, Worachet Kuntawunginn, Sarayut Tadsaichol, Montri Arsanok, Siriporn Sornsakrin, Chaiyaporn Chaisatit, Chaiyawat Mathavarat, Sasikanya Thaloengsok, Parat Boonyarangka, Chadin Thongpiam, Samandra Demons, Brian Vesely…
    Citation: Malaria Journal 2022 21:142
  18. Plasmodium knowlesi is a zoonotic malaria parasite that has gained increasing medical interest over the past two decades. This zoonotic parasitic infection is prevalent in Southeast Asia and causes many cases wit...

    Authors: Wenn-Chyau Lee, Fei Wen Cheong, Amirah Amir, Meng Yee Lai, Jia Hui Tan, Wei Kit Phang, Shahhaziq Shahari and Yee-Ling Lau
    Citation: Malaria Journal 2022 21:140
  19. The global malaria burden sometimes obscures that the genus Plasmodium comprises diverse clades with lineages that independently gave origin to the extant human parasites. Indeed, the differences between the huma...

    Authors: Ananias A. Escalante, Axl S. Cepeda and M. Andreína Pacheco
    Citation: Malaria Journal 2022 21:139
  20. During the twentieth century, there was an explosion in understanding of the malaria parasites infecting humans and wild primates. This was built on three main data sources: from detailed descriptive morpholog...

    Authors: Hans-Peter Fuehrer, Susana Campino and Colin J. Sutherland
    Citation: Malaria Journal 2022 21:138
  21. In the Republic of the Congo, malaria represents a major public health problem affecting all age groups. A regular surveillance of the current efficacy of first-line anti-malarial drugs is required in the face...

    Authors: Brice Pembet Singana, Prisca Nadine Casimiro, Brunelle Matondo Diassivi, Simon Charles Kobawila, Jean-Mermoz Youndouka, Leonardo K. Basco, Pascal Ringwald, Sébastien Briolant and Mathieu Ndounga
    Citation: Malaria Journal 2022 21:137
  22. Ghana has adopted and implemented intermittent preventive treatment using sulfadoxine-pyrimethamine (IPTp-SP) and insecticide-treated nets (ITNs) in an antenatal care (ANC) context to prevent malaria among pre...

    Authors: Virtue Fiawokome De-Gaulle, Joseph Kamgno, Verner N. Orish, Agnes Kotoh, Wilfred Mbacham, Harry Tagbor and Pascal Magnussen
    Citation: Malaria Journal 2022 21:136
  23. During the last two decades, researchers have suggested that the changes of malaria cases in African highlands were driven by climate change. Recently, a study claimed that the malaria cases (Plasmodium falciparu...

    Authors: Felipe Augusto Maurin Krsulovic, Timothy Peter Moulton, Mauricio Lima and Fabian Jaksic
    Citation: Malaria Journal 2022 21:135
  24. Artesunate–amodiaquine (ASAQ) and Artemether–lumefantrine (AL) are the recommended treatment for uncomplicated Plasmodium falciparum malaria in Liberia. Intermittent preventive treatment with sulfadoxine/pyrimeth...

    Authors: Victor S. Koko, Marian Warsame, Benjamin Vonhm, Moses K. Jeuronlon, Didier Menard, Laurence Ma, Fahn Taweh, Lekilay Tehmeh, Paye Nyansaiye, Oliver J. Pratt, Sei Parwon, Patrick Kamara, Magnus Asinya, Aaron Kollie and Pascal Ringwald
    Citation: Malaria Journal 2022 21:134
  25. Smoke from solid biomass cooking is often stated to reduce household mosquito levels and, therefore, malarial transmission. However, household air pollution (HAP) from solid biomass cooking is estimated to be ...

    Authors: Katherine E. Woolley, Suzanne E. Bartington, Francis D. Pope, Sheila M. Greenfield, Lucy S. Tusting, Malcolm J. Price and G. Neil Thomas
    Citation: Malaria Journal 2022 21:133
  26. Following a 30-year development process, RTS,S/AS01E (GSK, Belgium) is the first malaria vaccine to reach Phase IV assessments. The World Health Organization-commissioned Malaria Vaccine Implementation Programme ...

    Authors: Nicolas Praet, Kwaku Poku Asante, Marie-Cecile Bozonnat, Elaine Jacqueline Akité, Patrick Odum Ansah, Laurence Baril, Owusu Boahen, Yolanda Guerra Mendoza, Valerie Haine, Simon Kariuki, Mathieu Lamy, Kenneth Maleta, Randy Mungwira, Latif Ndeketa, Abraham Oduro, Bernhards Ogutu…
    Citation: Malaria Journal 2022 21:132
  27. The rise in Plasmodium falciparum resistance to dihydroartemisinin–piperaquine (DHA–PPQ) treatment has been documented in the Greater Mekong Subregion with associations with mutations in the P. falciparum chloroq...

    Authors: Nonlawat Boonyalai, Kirakarn Kirativanich, Chatchadaporn Thamnurak, Chantida Praditpol, Brian A. Vesely, Mariusz Wojnarski, John S. Griesenbeck and Norman C. Waters
    Citation: Malaria Journal 2022 21:130
  28. Accurate malaria diagnosis and appropriate treatment at local health facilities are critical to reducing morbidity and human reservoir of infectious gametocytes. The current study assessed the accuracy of mala...

    Authors: Wilfred Ouma Otambo, Julius O. Olumeh, Kevin O. Ochwedo, Edwin O. Magomere, Isaiah Debrah, Collins Ouma, Patrick Onyango, Harrysone Atieli, Wolfgang R. Mukabana, Chloe Wang, Ming-Chieh Lee, Andrew K. Githeko, Guofa Zhou, John Githure, James Kazura and Guiyun Yan
    Citation: Malaria Journal 2022 21:129
  29. Countries in malaria endemic regions are determinedly making an effort to achieve the global malaria elimination goals. In Ethiopia, too, all concerned bodies have given attention to this mission as one of the...

    Authors: Selomon Tefera, Temesgen Bekele, Kefelegn Getahun, Abiyot Negash and Tsige Ketema
    Citation: Malaria Journal 2022 21:128
  30. Roraima state is the northernmost state in Brazil and the primary border-crossing point between Brazil and Venezuela. The uncontrolled surge of malaria in Venezuela, coupled with mass migration of Venezuelans ...

    Authors: Erica Anne Wetzler, Paola Marchesini, Leopoldo Villegas and Sara Canavati
    Citation: Malaria Journal 2022 21:127
  31. Loss of efficacy of diagnostic tests may lead to untreated or mistreated malaria cases, compromising case management and control. There is an increasing reliance on rapid diagnostic tests (RDTs) for malaria di...

    Authors: Sabin S. Nundu, Hiroaki Arima, Shirley V. Simpson, Ben-Yeddy Abel Chitama, Yannick Bazitama Munyeku, Jean-Jacques Muyembe, Toshihiro Mita, Steve Ahuka, Richard Culleton and Taro Yamamoto
    Citation: Malaria Journal 2022 21:126
  32. Anopheles arabiensis, member species of the Anopheles gambiae complex, is the primary vector of malaria and is widely distributed in Ethiopia. Anopheles funestus, Anopheles pharoensis and Anopheles nili are secon...

    Authors: Tebiban Chanyalew, Gadisa Natea, Desalegn Amenu, Delenasaw Yewhalaw and Eba Alemayehu Simma
    Citation: Malaria Journal 2022 21:125
  33. Malaria is a life-threatening public health problem globally with particularly heavy burden in the sub-Saharan Africa including Sudan. The understanding of feeding preference of malaria vectors on different ho...

    Authors: Omnia Altahir, Hanadi AbdElbagi, Mustafa Abubakr, Emmanuel Edwar Siddig, Ayman Ahmed and Nouh Saad Mohamed
    Citation: Malaria Journal 2022 21:124
  34. Despite recent advances in treatment and prevention, the prevalence of cerebral malaria (CM) remains high globally, especially in children under 5 years old. As treatment improves, more children will survive e...

    Authors: Savannah Karmen-Tuohy, Sebastian M. Mboma, John T. Langfitt, Rachel Brim, Melissa Gladstone and Terrie E. Taylor
    Citation: Malaria Journal 2022 21:123
  35. Microscopic examination of Giemsa-stained blood films remains the reference standard for malaria parasite detection and quantification, but is undermined by difficulties in ensuring high-quality manual reading...

    Authors: Debashish Das, Ranitha Vongpromek, Thanawat Assawariyathipat, Ketsanee Srinamon, Kalynn Kennon, Kasia Stepniewska, Aniruddha Ghose, Abdullah Abu Sayeed, M. Abul Faiz, Rebeca Linhares Abreu Netto, Andre Siqueira, Serge R. Yerbanga, Jean Bosco Ouédraogo, James J. Callery, Thomas J. Peto, Rupam Tripura…
    Citation: Malaria Journal 2022 21:122
  36. The Global Fund alone contributed 56% of all international financing for malaria and has invested more than US$13.5 billion in malaria treatment, prevention, and control programmes by June 2021. These investme...

    Authors: Yakubu Alhassan, Duah Dwomoh, Susan Ama Amuasi, Justice Nonvignon, Harriet Bonful, Mary Tetteh, Kofi Agyabeng, Martha Kotey, Alfred E. Yawson and Samuel Bosomprah
    Citation: Malaria Journal 2022 21:120
  37. Due to increased travel from endemic countries, malaria occurs more frequently in non-endemic regions. It is a challenge for diagnostic laboratories in non-endemic countries to provide reliable results, as exp...

    Authors: Tania A. Khartabil, Yolanda B. de Rijke, Rob Koelewijn, Jaap J. van Hellemond and Henk Russcher
    Citation: Malaria Journal 2022 21:119
  38. Cytoadhesion and sequestration of Plasmodium falciparum infected red blood cells (iRBC) in the microvasculature of vital organs are a major cause of malaria pathology. Several studies have provided evidence on th...

    Authors: Samuel Odarkwei Blankson, Danielle Seri Dadjé, Nadjla Traikia, Maroufou J. Alao, Serge Ayivi, Annick Amoussou, Philippe Deloron, Nicaise Tuikue Ndam, Jacqueline Milet, Leonardo K. Basco, Yaw Aniweh and Rachida Tahar
    Citation: Malaria Journal 2022 21:115
  39. Investigating whether the multiplicity of Plasmodium falciparum infection (MOI) is related to pregnancy outcomes, is of interest in sub-Saharan area where malaria is highly endemic. The present study aimed to cha...

    Authors: Jean Erick Massamba, Jean Claude Djontu, Christevy Jeannhey Vouvoungui, Charles Kobawila and Francine Ntoumi
    Citation: Malaria Journal 2022 21:114
  40. Globally, 94% of malaria deaths occur in sub-Saharan Africa, and children under age 5 account for 70% of malaria-related mortality in the region. This study sought to examine differences between female-headed ...

    Authors: Daniel Iddrisu and Cheryl A. Moyer
    Citation: Malaria Journal 2022 21:112
  41. Highly sensitive and accurate malaria diagnostic tools are essential to identify asymptomatic low parasitaemia infections. This study evaluated the performance of histidine-rich protein 2 (HRP-2) based rapid d...

    Authors: Edjronké M. A. Benié, Kigbafori D. Silué, Xavier C. Ding, Issa Yeo, J. B. Assamoi, Karim Tuo, Akpa P. Gnagne, Lasme J. C. E. Esso, Jean T. Coulibaly, Serge-Brice Assi, Bassirou Bonfoh, William Yavo and Eliézer K. N’Goran
    Citation: Malaria Journal 2022 21:111

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