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  1. The use of data in targeting malaria control efforts is essential for optimal use of resources. This work provides a practical mechanism for prioritizing geographic areas for insecticide-treated net (ITN) dist...

    Authors: Alyssa J. Young, Will Eaton, Matt Worges, Honelgn Hiruy, Kolawole Maxwell, Bala Mohammed Audu, Madeleine Marasciulo, Charles Nelson, James Tibenderana and Tarekegn A. Abeku
    Citation: Malaria Journal 2022 21:10
  2. The GMZ2.6c malaria vaccine candidate is a multi-stage Plasmodium falciparum chimeric protein which contains a fragment of the sexual-stage Pfs48/45-6C protein genetically fused to GMZ2, a fusion protein of GLURP...

    Authors: Barbara Oliveira Baptista, Ana Beatriz Lopes de Souza, Evelyn Kety Pratt Riccio, Cesare Bianco-Junior, Paulo Renato Rivas Totino, João Hermínio Martins da Silva, Michael Theisen, Susheel Kumar Singh, Linda Eva Amoah, Marcelo Ribeiro-Alves, Rodrigo Medeiros Souza, Josué Costa Lima-Junior, Cláudio Tadeu Daniel-Ribeiro and Lilian Rose Pratt-Riccio
    Citation: Malaria Journal 2022 21:6
  3. Long-lasting insecticidal nets (LLINs) are the main vector control tool for pregnant women, but their efficacy may be compromised, in part, due to pyrethroid resistance. In 2017, the Ugandan Ministry of Health...

    Authors: Michelle E. Roh, Brenda Oundo, Grant Dorsey, Stephen Shiboski, Roly Gosling, M. Maria Glymour, Sarah G. Staedke, Adam Bennett, Hugh Sturrock and Arthur Mpimbaza
    Citation: Malaria Journal 2022 21:5
  4. The efficacies of artemisinin based combinations have been excellent in Africa, but also comprehensive evidence regarding their safety would be important. The aim of this review was to synthesize available evi...

    Authors: Dawit Getachew Assefa, Eden Dagnachew Zeleke, Wondwosen Molla, Nebiyu Mengistu, Ahmedin Sefa, Andualem Mebratu, Asresu Feleke Bate, Etaferaw Bekele, Gizachew Yesmaw and Eyasu Makonnen
    Citation: Malaria Journal 2022 21:4
  5. Genotyping of the three Plasmodium falciparum polymorphic genes, msp1, msp2 and glurp, has been adopted as a standard strategy to distinguish recrudescence from new infection in drug efficacy clinical trials. How...

    Authors: Wahib M. Atroosh, Yee-Ling Lau, Georges Snounou, Meram Azzani and Hesham M. Al-Mekhlafi
    Citation: Malaria Journal 2022 21:2
  6. Kra monkeys (Macaca fascicularis), a natural host of Plasmodium knowlesi, control parasitaemia caused by this parasite species and escape death without treatment. Knowledge of the disease progression and resilien...

    Authors: Mariko S. Peterson, Chester J. Joyner, Jessica A. Brady, Jennifer S. Wood, Monica Cabrera-Mora, Celia L. Saney, Luis L. Fonseca, Wayne T. Cheng, Jianlin Jiang, Stacey A. Lapp, Stephanie R. Soderberg, Mustafa V. Nural, Jay C. Humphrey, Allison Hankus, Deepa Machiah, Ebru Karpuzoglu…
    Citation: Malaria Journal 2021 20:486
  7. Over the past two decades, Zanzibar substantially reduced malaria burden. As malaria decreases, sustainable improvements in control interventions may increasingly depend on accurate knowledge of malaria risk f...

    Authors: Humphrey R. Mkali, Erik J. Reaves, Shabbir M. Lalji, Abdul-Wahid Al-mafazy, Joseph J. Joseph, Abdullah S. Ali, Faiza B. Abbas, Mohamed H. Ali, Wahida S. Hassan, Chonge Kitojo, Naomi Serbantez, Bilali I. Kabula, Ssanyu S. Nyinondi, Donal Bisanzio, Mike McKay, Erin Eckert…
    Citation: Malaria Journal 2021 20:485
  8. In Uganda, artemether-lumefantrine (AL) is first-line therapy and dihydroartemisinin-piperaquine (DP) second-line therapy for the treatment of uncomplicated malaria. This study evaluated the efficacy and safet...

    Authors: Chris Ebong, Asadu Sserwanga, Jane Frances Namuganga, James Kapisi, Arthur Mpimbaza, Samuel Gonahasa, Victor Asua, Sam Gudoi, Ruth Kigozi, James Tibenderana, John Bosco Bwanika, Agaba Bosco, Denis Rubahika, Daniel Kyabayinze, Jimmy Opigo, Damian Rutazana…
    Citation: Malaria Journal 2021 20:484

    The Correction to this article has been published in Malaria Journal 2022 21:37

  9. Ethiopia is one of the few countries in Africa where Plasmodium vivax commonly co-exists with Plasmodium falciparum, and which accounts for ~ 40% of the total number of malaria infections in the country. Regardle...

    Authors: Tsige Ketema, Ketema Bacha, Kefelegn Getahun and Quique Bassat
    Citation: Malaria Journal 2021 20:483
  10. Information on the foci of Plasmodium species infections is essential for any country heading towards elimination. Odisha, one of the malaria-endemic states of India is targeting elimination of malaria by 2030. T...

    Authors: Madhusmita Bal, Ramakanta Rana, Arundhuti Das, Hemant Kumar Khuntia, Nilam Somalkar, Niranjan Sahoo, Jyoti Ghosal, Sanghamitra Pati, Ambarish Dutta and Manoranjan Ranjit
    Citation: Malaria Journal 2021 20:482
  11. Malaria causes more than 200 million cases of illness and 400,000 deaths each year across 90 countries. The World Health Organization (WHO) set a goal for 35 countries to eliminate malaria by 2030, with an int...

    Authors: Kim A. Lindblade, Hong Li Xiao, Amanda Tiffany, Gawrie Galappaththy and Pedro Alonso
    Citation: Malaria Journal 2021 20:481
  12. Existing mechanisms of insecticide resistance are known to help the survival of mosquitoes following contact with chemical compounds, even though they could negatively affect the life-history traits of resista...

    Authors: Adandé A. Medjigbodo, Luc S. Djogbénou, Oswald Y. Djihinto, Romaric B. Akoton, Emmanuella Abbey, Rosaria M. Kakossou, Eric G. Sonounameto, Esther B. J. Salavi, Laurette Djossou and Athanase Badolo
    Citation: Malaria Journal 2021 20:480
  13. Plasmodium vivax blood-stage relapses originating from re-activating hypnozoites are a major barrier for control and elimination of this disease. Radical cure is a form of therapy capable of addressing this probl...

    Authors: John H. Huber, Cristian Koepfli, Guido España, Narimane Nekkab, Michael T. White and T. Alex Perkins
    Citation: Malaria Journal 2021 20:479
  14. The novel anti-malarial cipargamin (KAE609) has potent, rapid activity against Plasmodium falciparum. Transient asymptomatic liver function test elevations were previously observed in cipargamin-treated subjects ...

    Authors: Gilles Ndayisaba, Adoke Yeka, Kwaku Poku Asante, Martin P. Grobusch, Etienne Karita, Henry Mugerwa, Stephen Asiimwe, Abraham Oduro, Bakary Fofana, Seydou Doumbia, Jay Prakash Jain, Sarita Barsainya, Gerd A. Kullak-Ublick, Guoqin Su, Esther K. Schmitt, Katalin Csermak…
    Citation: Malaria Journal 2021 20:478
  15. Countries in the Greater Mekong sub-region (GMS) aim to eliminate all forms of malaria by 2030. In Cambodia and Vietnam, forest-goers are at an increased risk of malaria. Universal access to prompt diagnosis a...

    Authors: Mahesh Paudel, Kemi Tesfazghi, Hoa Nguyen, Sochea Phok, Shwetha Srinivasan and Jennifer Wheeler
    Citation: Malaria Journal 2021 20:477
  16. Efforts to improve the impact of long-lasting insecticidal nets (LLINs) should be informed by understanding of the causes of decay in effect. Holes in LLINs have been estimated to account for 7–11% of loss in ...

    Authors: Thomas Smith, Adrian Denz, Maurice Ombok, Nabie Bayoh, Hannah Koenker, Nakul Chitnis, Olivier Briet, Joshua Yukich and John E. Gimnig
    Citation: Malaria Journal 2021 20:476
  17. In March 2020, the government of Uganda implemented a strict lockdown policy in response to the COVID-19 pandemic. Interrupted time series analysis (ITSA) was performed to assess whether major changes in outpa...

    Authors: Jane F. Namuganga, Jessica Briggs, Michelle E. Roh, Jaffer Okiring, Yasin Kisambira, Asadu Sserwanga, James A. Kapisi, Emmanuel Arinaitwe, Chris Ebong, Isaac Ssewanyana, Catherine Maiteki-Ssebuguzi, Moses R. Kamya, Sarah G. Staedke, Grant Dorsey and Joaniter I. Nankabirwa
    Citation: Malaria Journal 2021 20:475
  18. Development of an effective vaccine against blood-stage malaria requires the induction of long-term immune responses. Plasmodium vivax Reticulocyte Binding Protein 1a (PvRBP1a) is a blood-stage parasite antigen w...

    Authors: Piyawan Kochayoo, Pattarawan Sanguansuttikul, Pongsakorn Thawornpan, Kittikorn Wangriatisak, John H. Adams, Francis B. Ntumngia and Patchanee Chootong
    Citation: Malaria Journal 2021 20:474
  19. Malaria, acute respiratory infections (ARIs) and diarrhoea are the leading causes of morbidity and mortality among children under 5 years old. Estimates of the malaria incidence are available from a previous s...

    Authors: Tinashe A. Tizifa, Alinune N. Kabaghe, Robert S. McCann, William Nkhono, Spencer Mtengula, Willem Takken, Kamija S. Phiri and Michele van Vugt
    Citation: Malaria Journal 2021 20:473
  20. The gold standard for diagnosing Plasmodium falciparum infection is microscopic examination of Giemsa-stained peripheral blood smears. The effectiveness of this procedure for infection surveillance and malaria co...

    Authors: Kevin O. Ochwedo, Collince J. Omondi, Edwin O. Magomere, Julius O. Olumeh, Isaiah Debrah, Shirley A. Onyango, Pauline W. Orondo, Benyl M. Ondeto, Harrysone E. Atieli, Sidney O. Ogolla, John Githure, Antony C. A. Otieno, Andrew K. Githeko, James W. Kazura, Wolfgang R. Mukabana and Yan Guiyan
    Citation: Malaria Journal 2021 20:472
  21. Model-based geostatistical (MBG) methods have been extensively used to map malaria risk using community survey data in low-resource settings where disease registries are incomplete or non-existent. However, th...

    Authors: Emanuele Giorgi, Peter M. Macharia, Jack Woodmansey, Robert W. Snow and Barry Rowlingson
    Citation: Malaria Journal 2021 20:471
  22. Malaria-associated anaemia, arising from symptomatic, asymptomatic and submicroscopic infections, is a significant cause of morbidity worldwide. Induced blood stage malaria volunteer infection studies (IBSM-VI...

    Authors: Stephen D. Woolley, Louise Marquart, John Woodford, Stephan Chalon, Joerg J. Moehrle, James S. McCarthy and Bridget E. Barber
    Citation: Malaria Journal 2021 20:470
  23. Anopheles arabiensis is a member of Anopheles gambiae complex and the main malaria vector in Sudan. There is insufficient population genetics data available on An. arabiensis for an understanding of vector popula...

    Authors: Mashair Sir El Khatim Mustafa, Zairi Jaal, Sumia Abu Kashawa and Siti Azizah Mohd Nor
    Citation: Malaria Journal 2021 20:469
  24. In Ethiopia, despite improvements in coverage and access, utilization of long-lasting insecticidal nets (LLINs) remains a challenge. Different household-level factors have been identified as associated with LL...

    Authors: Honelgn Nahusenay Hiruy, Ayele Zewde, Seth R. Irish, Semira Abdelmenan, Adugna Woyessa, Yonas Wuletaw, Hiwot Solomon, Mebrahtom Haile, Achamyelesh Sisay, Sheleme Chibsa, Alemayehu Worku, Josh Yukich, Yemane Berhane and Joseph Keating
    Citation: Malaria Journal 2021 20:468
  25. With effective vector control and case management, substantial progress has been made towards eliminating malaria on the islands of São Tomé and Príncipe (STP). This study assessed the dynamic changes in the g...

    Authors: Ying-An Chen, Tsen-Ju Shiu, Lien-Fen Tseng, Chien-Fu Cheng, Wei-Liang Shih, Arlindo Vicente de Assunção Carvalho and Kun-Hsien Tsai
    Citation: Malaria Journal 2021 20:467
  26. Central America and the island of Hispaniola have set out to eliminate malaria by 2030. However, since 2014 a notable upturn in the number of cases has been reported in the Mosquitia region shared by Nicaragua...

    Authors: Gustavo Fontecha, Alejandra Pinto, Osman Archaga, Sergio Betancourth, Lenin Escober, Jessica Henríquez, Hugo O. Valdivia, Alberto Montoya and Rosa Elena Mejía
    Citation: Malaria Journal 2021 20:465
  27. Malaria vector control in the Democratic Republic of the Congo is plagued by several major challenges, including inadequate infrastructure, lack of access to health care systems and preventative measures, and ...

    Authors: Janvier Bandibabone, Charles McLoughlin, Sévérin N’Do, Chimanuka Bantuzeko, Vital Byabushi, Muhigwa Jeanberckmans, Maite Guardiola, Bertin Zawadi, Abdoulaye Diabaté, Jorian Prudhomme, Thomas Walker and Louisa A. Messenger
    Citation: Malaria Journal 2021 20:464
  28. Malaria is one of the deadliest diseases in the world, particularly in Africa. As such, resistance to anti-malarial drugs is one of the most important problems in terms of global malaria control. This study as...

    Authors: Pedro Berzosa, Irene Molina de la Fuente, Thuy-Huong Ta-Tang, Vicenta González, Luz García, Ana Rodríguez-Galet, Ramón Díaz-Regañón, Rosario Galán, Laura Cerrada-Gálvez, Policarpo Ncogo, Matilde Riloha and Agustin Benito
    Citation: Malaria Journal 2021 20:463
  29. Molecular diagnostic tools have been incorporated in insecticide resistance monitoring programmes to identify underlying genetic basis of resistance and develop early warning systems of vector control failure....

    Authors: Sharon Mwagira-Maina, Steven Runo, Lucy Wachira, Stanley Kitur, Sarah Nyasende, Brigid Kemei, Eric Ochomo, Damaris Matoke-Muhia, Charles Mbogo and Luna Kamau
    Citation: Malaria Journal 2021 20:461
  30. A detailed analysis of household and individual level Plasmodium infection patterns in two low-endemic districts of Meghalaya was undertaken to better understand the epidemiology of malaria in northeast India.

    Authors: Rajiv Sarkar, Anne Kessler, Bandapkupar Mawkhlieng, Steven A. Sullivan, Mark L. Wilson, Jane M. Carlton and Sandra Albert
    Citation: Malaria Journal 2021 20:460
  31. Use of long-lasting insecticidal nets (LLINs), indoor residual spraying (IRS), community-based malaria education, prompt diagnosis and treatment are key programme components of malaria prevention and control i...

    Authors: Abebe Asale, Zewdu Abro, Bayu Enchalew, Alayu Teshager, Aklilu Belay, Menale Kassie and Clifford Maina Mutero
    Citation: Malaria Journal 2021 20:459
  32. In April 2017, the Thai Ministry of Public Health (MoPH) was alerted to a potential malaria outbreak among civilians and military personnel in Sisaket Province, a highly forested area bordering Cambodia. The o...

    Authors: Michelle E. Roh, Kanyarat Lausatianragit, Nithinart Chaitaveep, Krisada Jongsakul, Prayuth Sudathip, Chatree Raseebut, Sutchana Tabprasit, Prasert Nonkaew, Michele Spring, Montri Arsanok, Parat Boonyarangka, Sabaithip Sriwichai, Piyaporn Sai-ngam, Chaiyaporn Chaisatit, Peerapol Pokpong, Preecha Prempree…
    Citation: Malaria Journal 2021 20:458
  33. Malaria is a global health problem for which novel therapeutic compounds are needed. To this end, a recently published novel family of antiplasmodial macrolides, strasseriolides AD, was herein subjected to in vi...

    Authors: Frederick Annang, Guiomar Pérez-Moreno, Caridad Díaz, Victor González-Menéndez, Nuria de Pedro Montejo, José Pérez del Palacio, Paula Sánchez, Scott Tanghe, Ana Rodriguez, Ignacio Pérez-Victoria, Juan Cantizani, Luis M. Ruiz-Pérez, Olga Genilloud, Fernando Reyes, Francisca Vicente and Dolores González-Pacanowska
    Citation: Malaria Journal 2021 20:457
  34. The World Health Organization (WHO) recommends prompt malaria diagnosis with either microscopy or malaria rapid diagnostic tests (RDTs) and treatment with an effective anti-malarial, as key interventions to co...

    Authors: Ruth N. Kigozi, JohnBaptist Bwanika, Emily Goodwin, Peter Thomas, Patrick Bukoma, Persis Nabyonga, Fred Isabirye, Paul Oboth, Carol Kyozira, Mame Niang, Kassahun Belay, Gloria Sebikaari, James K. Tibenderana and Sam Siduda Gudoi
    Citation: Malaria Journal 2021 20:456
  35. Access to healthcare is important in controlling malaria burden and, as a result, distance or travel time to health facilities is often a significant predictor in modelling malaria prevalence. Adding new healt...

    Authors: Kok Ben Toh, Justin Millar, Paul Psychas, Benjamin Abuaku, Collins Ahorlu, Samuel Oppong, Kwadwo Koram and Denis Valle
    Citation: Malaria Journal 2021 20:455
  36. Thailand is committed to eliminating malaria by 2024. From 2013 to 2020, the total number of malaria cases have decreased, from 37,741 to 4474 (an 88.1% reduction). However, infections with Plasmodium knowlesi, a...

    Authors: Rungniran Sugaram, Patcharida Boondej, Suttipat Srisutham, Chanon Kunasol, Watcharee Pagornrat, Usa Boonyuen, Arjen M Dondorp, Aungkana Saejeng, Prayuth Sudathip and Mallika Imwong
    Citation: Malaria Journal 2021 20:454
  37. As part of malaria prevention and control efforts, the distribution and density of malaria mosquitoes requires continuous monitoring. Resources for long-term surveillance of malaria vectors, however, are often...

    Authors: Marilyn Milumbu Murindahabi, Arash Hoseni, L. C. Corné Vreugdenhil, Arnold J. H. van Vliet, Jackie Umupfasoni, Alphonse Mutabazi, Emmanuel Hakizimana, P. Marijn Poortvliet, Leon Mutesa, Willem Takken and Constantianus J. M. Koenraadt
    Citation: Malaria Journal 2021 20:453
  38. RTS,S/AS01, the leading malaria vaccine has been recommended by the WHO for widespread immunization of children at risk. RTS,S/AS01-induced anti-CSP IgG antibodies are associated with the vaccine efficacy. Her...

    Authors: Robert M. Mugo, Kennedy Mwai, Jedidah Mwacharo, Faiz M. Shee, Jennifer N. Musyoki, Juliana Wambua, Edward Otieno, Philip Bejon and Francis M. Ndungu
    Citation: Malaria Journal 2021 20:452
  39. The devastating public health impact of malaria has prompted the need for effective interventions. Malaria control gained traction after the introduction of artemisinin-based combination therapy (ACT). However...

    Authors: Afolabi Owoloye, Michael Olufemi, Emmanuel T. Idowu and Kolapo M. Oyebola
    Citation: Malaria Journal 2021 20:451
  40. Malaria is a preventable disease that causes huge morbidity and mortality in malaria-endemic areas, especially among children and pregnant women. The malaria control programme focuses on the prevention of mosq...

    Authors: Verner N. Orish, Raymond Saa-Eru Maalman, Otchere Y. Donkor, Barbara Yordanis Henandez Ceruantes, Eric Osei, Hubert Amu, Prince Kubi Appiah, Kennedy Diema Konlan, Hadiru Mumuni, Eunji Kim, Siwoo Kim, Hajun Jung, Jones Ofori-Amoah, Philip Kofie, Martin Adjuik, Robert Kaba Alhassan…
    Citation: Malaria Journal 2021 20:450
  41. The study aimed to analyse the likelihood of imported malaria in people with a suggestive clinical picture and its distinctive characteristics in a hospital in the south of Madrid, Spain.

    Authors: Alejandro Garcia-Ruiz de Morales, Covadonga Morcate, Elena Isaba-Ares, Ramon Perez-Tanoira and Jose A. Perez-Molina
    Citation: Malaria Journal 2021 20:449
  42. In recent years, the incidence rate of vivax malaria recurrence still had 3.1% in Yunnan Province population after eradication therapy using primaquine (PQ). In order to understand the specific failure reasons...

    Authors: Ying Dong, Herong Huang, Yan Deng, Yanchun Xu, Mengni Chen, Yan Liu and Canglin Zhang
    Citation: Malaria Journal 2021 20:448
  43. The return of chloroquine-sensitive Plasmodium falciparum in sub-Saharan Africa countries offers the opportunity for the reintroduction of chloroquine (CQ) either in combination with other drugs or as a single th...

    Authors: Kwame Kumi Asare, Justice Africa, Jennifer Mbata and Yeboah Kwaku Opoku
    Citation: Malaria Journal 2021 20:447
  44. In the Greater Mekong Subregion, adults are at highest risk for malaria, particularly those who visit forests. The absence of effective vector control strategies and limited periods of exposure during forest v...

    Authors: Monnaphat Jongdeepaisal, Mom Ean, Chhoeun Heng, Thoek Buntau, Rupam Tripura, James J. Callery, Thomas J. Peto, Franca Conradis-Jansen, Lorenz von Seidlein, Panarasri Khonputsa, Kulchada Pongsoipetch, Ung Soviet, Siv Sovannaroth, Christopher Pell and Richard J. Maude
    Citation: Malaria Journal 2021 20:446
  45. Plasmodium interspersed repeat (pir) is the largest multigene family in the genomes of most Plasmodium species. A variety of functions for the PIR proteins which they encode have been proposed, including antigeni...

    Authors: Timothy S. Little, Deirdre A. Cunningham, Audrey Vandomme, Carlos Talavera Lopez, Sarah Amis, Christopher Alder, John W. G. Addy, Sarah McLaughlin, Caroline Hosking, George Christophides, Adam J. Reid and Jean Langhorne
    Citation: Malaria Journal 2021 20:445
  46. Malaria elimination in Brazil poses several challenges, including the control of Plasmodium falciparum foci and the hidden burden of Plasmodium vivax in pregnancy. Maternal malaria and fetal health outcomes were ...

    Authors: Julio Abel Seijas-Chávez, Melissa S. Nolan, Mary K. Lynn, Maria José Francalino da Rocha, Muana da Costa Araújo, Fernando Luiz Affonso Fonseca and Gabriel Zorello Laporta
    Citation: Malaria Journal 2021 20:444

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