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  1. Resistance to anti-malarial drugs is a widespread problem for control programmes for this devastating disease. Molecular tests are available for many anti-malarial drugs and are useful tools for the surveillan...

    Authors: Mahamadou Diakite, Eric A Achidi, Olivia Achonduh, Rachel Craik, Abdoulaye A Djimde, Marie-Solange B Evehe, Angie Green, Christina Hubbart, Muntasir Ibrahim, Anna Jeffreys, Baldip K Khan, Francis Kimani, Dominic P Kwiatkowski, Wilfred F Mbacham, Sabah Omar Jezan, Jean Bosco Ouedraogo…
    Citation: Malaria Journal 2011 10:250
  2. In Central and South America and Eastern and Southern Africa, Plasmodium vivax infections accounts for 71-81% and 5% of malaria cases, respectively. In these areas, chloroquine (CQ) remains the treatment of choic...

    Authors: Insaf F Khalil, Michael Alifrangis, Camilla Recke, Lotte C Hoegberg, Anita Ronn, Ib C Bygbjerg and Claus Koch
    Citation: Malaria Journal 2011 10:249
  3. Plasmodium falciparum malaria remains a leading health problem in Africa and its control is seriously challenged by drug resistance. Although resistance to the sulphadoxine-pyrimethamine (SP) is widespread, this ...

    Authors: Bianca E Gama, Guilhermina AL Pereira-Carvalho, Florbela JI Lutucuta Kosi, Natália K Almeida de Oliveira, Filomeno Fortes, Philip J Rosenthal, Virgílio E do Rosário, Cláudio Tadeu Daniel-Ribeiro and Maria de Fátima Ferreira-da-Cruz
    Citation: Malaria Journal 2011 10:248
  4. Effective mass drug administration (MDA) with anti-malarial drugs can clear the human infectious reservoir for malaria and thereby interrupt malaria transmission. The likelihood of success of MDA depends on th...

    Authors: Seif A Shekalaghe, Chris Drakeley, Sven van den Bosch, Roel ter Braak, Wouter van den Bijllaardt, Charles Mwanziva, Salimu Semvua, Alutu Masokoto, Frank Mosha, Karina Teelen, Rob Hermsen, Lucy Okell, Roly Gosling, Robert Sauerwein and Teun Bousema
    Citation: Malaria Journal 2011 10:247
  5. Malaria is a major health issue in French Guiana. Amerindian communities remain the most affected. A previous study in Camopi highlighted the predominant role of environmental factors in the occurrence of mala...

    Authors: Aurélia Stefani, Matthieu Hanf, Mathieu Nacher, Romain Girod and Bernard Carme
    Citation: Malaria Journal 2011 10:246
  6. This is an investigation of anti-malarial molecular markers coupled with a therapeutic efficacy test of chloroquine (CQ) against falciparum malaria in an area of unstable malaria in Lahj Governorate, Yemen. Th...

    Authors: Reem A Mubjer, Ahmed A Adeel, Michael L Chance and Amir A Hassan
    Citation: Malaria Journal 2011 10:245
  7. Real-time PCR is a sensitive and specific method for the analysis of Plasmodium DNA. However, prior purification of genomic DNA from blood is necessary since PCR inhibitors and quenching of fluorophores from bloo...

    Authors: Brian J Taylor, Kimberly A Martin, Eliana Arango, Olga M Agudelo, Amanda Maestre and Stephanie K Yanow
    Citation: Malaria Journal 2011 10:244
  8. Whilst some populations have recently experienced dramatic declines in malaria, the majority of those most at risk of Plasmodium falciparum malaria still lack access to effective treatment with artemisinin combin...

    Authors: Shunmay Yeung, Edith Patouillard, Henrietta Allen and Duong Socheat
    Citation: Malaria Journal 2011 10:243
  9. Pyronaridine (PN) and chloroquine (CQ) are structurally related anti-malarial drugs with primarily the same mode of action. However, PN is effective against several multidrug-resistant lines of Plasmodium falcipa...

    Authors: Kanyanan Kritsiriwuthinan, Sastra Chaotheing, Philip J Shaw, Chayaphat Wongsombat, Porntip Chavalitshewinkoon-Petmitr and Sumalee Kamchonwongpaisan
    Citation: Malaria Journal 2011 10:242
  10. Glucose-6-phosphate dehydrogenase (G6PD) deficiency is common in populations living in malaria endemic areas. G6PD genotype and phenotype were determined for malaria patients enrolled in the chlorproguanil-dap...

    Authors: Nick Carter, Allan Pamba, Stephan Duparc and John N Waitumbi
    Citation: Malaria Journal 2011 10:241
  11. The community case management of malaria (CCMm) is now an established route for distribution of artemisinin-based combination therapy (ACT) in rural areas, but the feasibility and acceptability of the approach...

    Authors: Patricia Akweongo, Peter Agyei-Baffour, Morankar Sudhakar, Bertha N Simwaka, Amadou T Konaté, Philip B Adongo, Edmund NL Browne, Ayalew Tegegn, Doreen Ali, Abdoulaye Traoré, Mary Amuyunzu-Nyamongo, Franco Pagnoni and Guy Barnish
    Citation: Malaria Journal 2011 10:240
  12. Congenital malaria has been considered a rare event; however, recent reports have shown frequencies ranging from 3% to 54.2% among newborns of mothers who had suffered malaria during pregnancy. There are only ...

    Authors: Juan G Piñeros-Jiménez, Gonzalo Álvarez, Alberto Tobón, Margarita Arboleda, Sonia Carrero and Silvia Blair
    Citation: Malaria Journal 2011 10:239
  13. Artemether-lumefantrine (ALu) replaced sulphadoxine-pymimethamine (SP) as the official first-line anti-malarial in Tanzania in November 2006. So far, artemisinin combination therapy (ACT) is contra-indicated d...

    Authors: Frank M Ringsted, Isolide S Massawe, Martha M Lemnge and Ib C Bygbjerg
    Citation: Malaria Journal 2011 10:238
  14. The use of artemisinin-based combination therapy (ACT) is currently recommended for treating uncomplicated malaria. The objective was to assess the efficacy and safety of repeated administrations of two fixed-...

    Authors: Jean-Louis A Ndiaye, Babacar Faye, Ali Gueye, Roger Tine, Daouda Ndiaye, Corinne Tchania, Ibrahima Ndiaye, Aichatou Barry, Badara Cissé, Valérie Lameyre and Oumar Gaye
    Citation: Malaria Journal 2011 10:237
  15. The Solomon Islands National Malaria Programme is currently focused on intensified control and progressive elimination. Recent control efforts in Isabel Province have reduced their malaria incidence to 2.6/1,0...

    Authors: Matthew O'Sullivan, Geoffrey Kenilorea, Yuka Yamaguchi, Albino Bobogare, Landry Losi, Jo-An Atkinson, Andrew Vallely, Maxine Whittaker, Marcel Tanner and Rushika Wijesinghe
    Citation: Malaria Journal 2011 10:235
  16. Malaria is a major public health issue in Burundi in terms of both morbidity and mortality, with around 2.5 million clinical cases and more than 15,000 deaths each year. It is still the single main cause of mo...

    Authors: Hermenegilde Nkurunziza, Albrecht Gebhardt and Jürgen Pilz
    Citation: Malaria Journal 2011 10:234
  17. This study was conducted to evaluate whether a selection of South African ethnomedicinal plants included in this study displayed insecticidal properties when screened against adult stages of the mosquito.

    Authors: Rajendra Maharaj, Vinesh Maharaj, Neil R Crouch, Niresh Bhagwandin, Peter I Folb, Pamisha Pillay and Reshma Gayaram
    Citation: Malaria Journal 2011 10:233
  18. The effectiveness of anti-vectorial malaria protective measures in travellers and expatriates is hampered by incorrect compliance. The objective of the present study was to identify the determinants of complia...

    Authors: Emmanuel Sagui, Noémie Resseguier, Vanessa Machault, Lénaïck Ollivier, Eve Orlandi-Pradines, Gaetan Texier, Frédéric Pages, Remy Michel, Bruno Pradines, Sébastien Briolant, Alain Buguet, Catherine Tourette-Turgis and Christophe Rogier
    Citation: Malaria Journal 2011 10:232
  19. Drug resistance of falciparum malaria is a global problem. Sulphadoxine/pyrimethamine-resistant and mefloquine-resistant strains of falciparum malaria have spread in Southeast Asia at lightning speed in 1980s-...

    Authors: Jianping Song, Duong Socheat, Bo Tan, Suon Seila, Ying Xu, Fengzhen Ou, Sreng Sokunthea, Leap Sophorn, Chongjun Zhou, Changsheng Deng, Qi Wang and Guoqiao Li
    Citation: Malaria Journal 2011 10:231
  20. Adverse drug reactions (ADRs) contribute to ill-health or life-threatening outcomes of therapy during management of infectious diseases. The exposure to anti-malarial and use of mobile phone technology to repo...

    Authors: Ahmed A Adedeji, Bilqees Sanusi, Azeez Tella, Motunrayo Akinsanya, Olubusola Ojo, Mufliat O Akinwunmi, Olubukola A Tikare, Isiaka A Ogunwande, Omobola A Ogundahunsi, Olajide O Ayilara, Taofeeqah T Ademola, Fatai A Fehintola and Olumide AT Ogundahunsi
    Citation: Malaria Journal 2011 10:230
  21. The aim of this study was to investigate the profile of antibodies against several antigens of Plasmodium vivax and Plasmodium falciparum in Mandalay, Myanmar.

    Authors: Tong-Soo Kim, Hyung-Hwan Kim, Jung-Yeon Kim, Yoon Kong, Byoung-Kuk Na, Khin Lin, Sung-Ung Moon, Yeon-Joo Kim, Myoung-Hee Kwon, Youngjoo Sohn, Hyuck Kim and Hyeong-Woo Lee
    Citation: Malaria Journal 2011 10:228
  22. Despite massive anti-malaria campaigns across the subcontinent, effective access to intermittent preventive treatment (IPTp) and insecticide-treated nets (ITNs) among pregnant women remain low in large parts o...

    Authors: Joseph C Okeibunor, Bright C Orji, William Brieger, Gbenga Ishola, Emmanuel 'Dipo Otolorin, Barbara Rawlins, Enobong U Ndekhedehe, Nkechi Onyeneho and Günther Fink
    Citation: Malaria Journal 2011 10:227
  23. Malaria rapid diagnostic tests (RDTs) have generally been found reliable and cost-effective. In Burkina Faso, the adherence of prescribers to the negative test result was found to be poor. Moreover, the test a...

    Authors: Zeno Bisoffi, Sodiomon B Sirima, Filip Meheus, Claudia Lodesani, Federico Gobbi, Andrea Angheben, Halidou Tinto, Bouma Neya, Klara Van den Ende, Annalisa Romeo and Jef Van den Ende
    Citation: Malaria Journal 2011 10:226
  24. Community engagement and participation has played a critical role in successful disease control and elimination campaigns in many countries. Despite this, its benefits for malaria control and elimination are y...

    Authors: Jo-An Atkinson, Andrew Vallely, Lisa Fitzgerald, Maxine Whittaker and Marcel Tanner
    Citation: Malaria Journal 2011 10:225
  25. GlaxoSmithKline Biologicals and the PATH Malaria Vaccine Initiative are working in partnership to develop a malaria vaccine to protect infants and children living in malaria endemic regions of sub-Saharan Afri...

    Authors: Amanda Leach, Johan Vekemans, Marc Lievens, Opokua Ofori-Anyinam, Conor Cahill, Seth Owusu-Agyei, Salim Abdulla, Eusebio Macete, Patricia Njuguna, Barbara Savarese, Christian Loucq and W Ripley Ballou
    Citation: Malaria Journal 2011 10:224
  26. A pivotal phase III study of the RTS,S/AS01 malaria candidate vaccine is ongoing in several research centres across Africa. The development and establishment of quality systems was a requirement for trial cond...

    Authors: Christine Swysen, Johan Vekemans, Myriam Bruls, Sunny Oyakhirome, Chris Drakeley, Peter Kremsner, Brian Greenwood, Opokua Ofori-Anyinam, Brenda Okech, Tonya Villafana, Terrell Carter, Barbara Savarese, Adriano Duse, Andrea Reijman, Charlotte Ingram, John Frean…
    Citation: Malaria Journal 2011 10:223
  27. There has been much debate about the appropriate statistical methodology for the evaluation of malaria field studies and the challenges in interpreting data arising from these trials.

    Authors: Marc Lievens, John J Aponte, John Williamson, Bruno Mmbando, Ali Mohamed, Philip Bejon and Amanda Leach
    Citation: Malaria Journal 2011 10:222
  28. An effective malaria vaccine, deployed in conjunction with other malaria interventions, is likely to substantially reduce the malaria burden. Efficacy against severe malaria will be a key driver for decisions ...

    Authors: Johan Vekemans, Kevin Marsh, Brian Greenwood, Amanda Leach, William Kabore, Solange Soulanoudjingar, Kwaku Poku Asante, Daniel Ansong, Jennifer Evans, Jahit Sacarlal, Philip Bejon, Portia Kamthunzi, Nahya Salim, Patricia Njuguna, Mary J Hamel, Walter Otieno…
    Citation: Malaria Journal 2011 10:221
  29. Malaria in the 21st century is showing signs of declining over much of its distribution, including several countries in Africa where previously this was not thought to be feasible. Yet for the most part the strat...

    Authors: Clive Shiff, Phil Thuma, David Sullivan and Sungano Mharakurwa
    Citation: Malaria Journal 2011 10:220
  30. Chemical insecticides against mosquitoes are a major component of malaria control worldwide. Fungal entomopathogens formulated as biopesticides and applied as insecticide residual sprays could augment current ...

    Authors: Justin George, Simon Blanford, Michael J Domingue, Matthew B Thomas, Andrew F Read and Thomas C Baker
    Citation: Malaria Journal 2011 10:219
  31. Globally, the monitoring of prompt and effective treatment for malaria with artemisinin combination therapy (ACT) is conducted largely through household surveys. This measure; however, provides no information ...

    Authors: Bernadette Hensen, Lucy Smith Paintain, Rima Shretta, Jane Bruce, Caroline Jones and Jayne Webster
    Citation: Malaria Journal 2011 10:218
  32. Acute renal failure is a common complication of severe malaria in adults, and without renal replacement therapy (RRT), it carries a poor prognosis. Even when RRT is available, delaying its initiation may incre...

    Authors: Josh Hanson, Md Mahtab Uddin Hasan, Annick A Royakkers, Shamsul Alam, Prakaykaew Charunwatthana, Richard J Maude, Sam T Douthwaite, Emran Bin Yunus, Murty L Mantha, Marcus J Schultz, M Abul Faiz, Nicholas J White, Nicholas P Day and Arjen M Dondorp
    Citation: Malaria Journal 2011 10:217
  33. Anopheles lesteri is a primary vector of Plasmodium spp. in central China. A complete understanding of vector population structure and the processes responsible for the differentiation is important to the vector-...

    Authors: Manni Yang, Yajun Ma and Jing Wu
    Citation: Malaria Journal 2011 10:216
  34. Anopheles gambiae M and S molecular forms, the major malaria vectors in the Afro-tropical region, are ongoing a process of ecological diversification and adaptive lineage splitting, which is affecting malaria tra...

    Authors: Federica Santolamazza, Beniamino Caputo, Maria Calzetta, José L Vicente, Emiliano Mancini, Vincenzo Petrarca, João Pinto and Alessandra della Torre
    Citation: Malaria Journal 2011 10:215
  35. In Ethiopia, malaria is caused by Plasmodium falciparum and Plasmodium vivax, and anti-malarial drug resistance is the most pressing problem confronting control of the disease. Since co-infection by both species ...

    Authors: Patricia Mula, Amalia Fernández-Martínez, Aida de Lucio, Jose Manuel Ramos, Francisco Reyes, Vicenta González, Agustín Benito and Pedro Berzosa
    Citation: Malaria Journal 2011 10:214
  36. Monoclonal antibodies to Plasmodium lactate dehydrogenase (pLDH) have been previously used to format immunochromatographic tests for the diagnosis of malaria. Using pLDH as an antigen has several advantages as a ...

    Authors: Robert C Piper, Ian Buchanan, Young Ho Choi and Michael T Makler
    Citation: Malaria Journal 2011 10:213
  37. Tafenoquine is an 8-aminoquinoline being developed for radical cure (blood and liver stage elimination) of Plasmodium vivax. During monotherapy treatment, the compound exhibits slow parasite and fever clearance t...

    Authors: Geoffrey S Dow, Montip Gettayacamin, Pranee Hansukjariya, Rawiwan Imerbsin, Srawuth Komcharoen, Jetsumon Sattabongkot, Dennis Kyle, Wilbur Milhous, Simon Cozens, David Kenworthy, Anne Miller, Jim Veazey and Colin Ohrt
    Citation: Malaria Journal 2011 10:212
  38. Plasmodium falciparum malaria remains endemic in sub-Saharan Africa including Ghana. The epidemiology of malaria in special areas, such as mining areas needs to be monitored and controlled. Newmont Ghana Gold Lim...

    Authors: Kwaku P Asante, Charles Zandoh, Dominic B Dery, Charles Brown, George Adjei, Yaw Antwi-Dadzie, Martin Adjuik, Kofi Tchum, David Dosoo, Seeba Amenga-Etego, Christine Mensah, Kwabena B Owusu-Sekyere, Chris Anderson, Gary Krieger and Seth Owusu-Agyei
    Citation: Malaria Journal 2011 10:211
  39. Asymptomatic carriers of Plasmodium falciparum serve as a reservoir of parasites for malaria transmission. Identification and treatment of asymptomatic carriers within a region may reduce the parasite reservoir a...

    Authors: Steven E Kern, Alfred B Tiono, Michael Makanga, Adama Dodji Gbadoé, Zulfiqarali Premji, Oumar Gaye, Issaka Sagara, David Ubben, Marc Cousin, Fiyinfolu Oladiran, Oliver Sander and Bernhards Ogutu
    Citation: Malaria Journal 2011 10:210
  40. In vivo efficacy assessments of the first-line treatments for Plasmodium falciparum malaria are essential for ensuring effective case management. In Ethiopia, artemether-lumefantrine (AL) has been the first-line ...

    Authors: Jimee Hwang, Bereket H Alemayehu, David Hoos, Zenebe Melaku, Samuel G Tekleyohannes, Takele Teshi, Sintayehu G Birhanu, Leykun Demeke, Kedir Gobena, Moges Kassa, Daddi Jima, Richard Reithinger, Henry Nettey, Michael Green, Joseph L Malone, S Patrick Kachur…
    Citation: Malaria Journal 2011 10:209
  41. Insecticide-treated nets (ITNs) and indoor residual spraying (IRS) are currently the preferred methods of malaria vector control. In many cases, these methods are used together in the same households, especial...

    Authors: Fredros O Okumu and Sarah J Moore
    Citation: Malaria Journal 2011 10:208
  42. The most common pesticide products for controlling malaria-transmitting mosquitoes combine two distinct modes of action: 1) conventional insecticidal activity which kills mosquitoes exposed to the pesticide an...

    Authors: Gerry F Killeen, Nakul Chitnis, Sarah J Moore and Fredros O Okumu
    Citation: Malaria Journal 2011 10:207
  43. The Anopheles gambiae gSG6 is an anopheline-specific salivary protein which helps female mosquitoes to efficiently feed on blood. Besides its role in haematophagy, gSG6 is immunogenic and elicits in exposed indiv...

    Authors: Cinzia Rizzo, Raffaele Ronca, Gabriella Fiorentino, Valentina D Mangano, Sodiomon B Sirima, Issa Nèbiè, Vincenzo Petrarca, David Modiano and Bruno Arcà
    Citation: Malaria Journal 2011 10:206
  44. A global proteomic strategy was used to identify proteins, which are differentially expressed in the murine model of severe malaria in the hope of facilitating future development of novel diagnostic, disease m...

    Authors: Evelyn N Gitau, Gilbert O Kokwaro, Charles RJC Newton and Stephen A Ward
    Citation: Malaria Journal 2011 10:205
  45. Early diagnosis and prompt effective case management are important components of any malaria elimination strategy. Tafea Province, Vanuatu has a rich history of traditional practices and beliefs, which have be...

    Authors: Anna Tynan, Jo-An Atkinson, Hilson Toaliu, George Taleo, Lisa Fitzgerald, Maxine Whittaker, Ian Riley, Mark Schubert and Andrew Vallely
    Citation: Malaria Journal 2011 10:204
  46. Malaria is reportedly receding in different epidemiological settings, but local long-term surveys are limited. At Mlomp dispensary in south-western Senegal, an area of moderate malaria transmission, year-round...

    Authors: Philippe Brasseur, Malick Badiane, Moustafa Cisse, Patrice Agnamey, Michel T Vaillant and Piero L Olliaro
    Citation: Malaria Journal 2011 10:203

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