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  1. Plasmodium falciparum drug resistance represents a major health problem in malaria endemic countries. The mechanisms of resistance are not fully elucidated. Recently, an association between putative transporter g...

    Authors: Sandrine Cojean, Alain Noël, Dimitri Garnier, Véronique Hubert, Jacques Le Bras and Rémy Durand

    Citation: Malaria Journal 2006 5:24

    Content type: Research

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  2. The Plasmodium species that infect rodents, particularly Plasmodium berghei and Plasmodium yoelii, are useful to investigate host-parasite interactions. The mosquito species that act as vectors of human plasmodia...

    Authors: Friedrich Frischknecht, Beatrice Martin, Isabelle Thiery, Catherine Bourgouin and Robert Menard

    Citation: Malaria Journal 2006 5:23

    Content type: Methodology

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  3. Malaria transmission varies from one country to another and there are also local differences in time and space. An important variable when explaining the variability in transmission is the breeding behaviour o...

    Authors: Jorge Cano, Miguel Ángel Descalzo, Marta Moreno, Zhaoguo Chen, Sisinio Nzambo, Leonardo Bobuakasi, Jesús N Buatiche, Melchor Ondo, Francisco Micha and Agustín Benito

    Citation: Malaria Journal 2006 5:21

    Content type: Research

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  4. Malaria is an annual killer of over one million people globally and its essential co-morbidity is anaemia. Cord blood, because of its rich mix of foetal and adult haemoglobin, high platelet and WBC counts, hyp...

    Authors: Niranjan Bhattacharya

    Citation: Malaria Journal 2006 5:20

    Content type: Methodology

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  5. Knowledge of the ecological differences between the molecular forms of Anopheles gambiae and their sibling species, An. arabiensis might lead to understanding their unique contribution to disease transmission and...

    Authors: Alpha S Yaro, Adama Dao, Abdoulaye Adamou, Jacob E Crawford, José MC Ribeiro, Robert Gwadz, Sekou F Traoré and Tovi Lehmann

    Citation: Malaria Journal 2006 5:19

    Content type: Research

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  6. Studies of malaria in well-defined cohorts offer important data about the epidemiology of this complex disease, but few have been done in urban African populations. To generate a sampling frame for a longitudi...

    Authors: Jennifer C Davis, Tamara D Clark, Sarah K Kemble, Nalugwa Talemwa, Denise Njama-Meya, Sarah G Staedke and Grant Dorsey

    Citation: Malaria Journal 2006 5:18

    Content type: Methodology

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  7. Malaria cases on the highlands west of Mount Kenya have been noticed since 10 – 20 years ago. It was not clear whether these cases were introduced from the nearby lowland or resulted from local transmission be...

    Authors: Hong Chen, Andrew K Githeko, Guofa Zhou, John I Githure and Guiyun Yan

    Citation: Malaria Journal 2006 5:17

    Content type: Research

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  8. Appropriate monitoring of vector resistance to insecticides is an integral component of planning and evaluation of insecticide use in malaria control programmes. The malaria vectors Anopheles gambiae s.s. and Ano...

    Authors: Katrijn Verhaeghen, Wim Van Bortel, Patricia Roelants, Thierry Backeljau and Marc Coosemans

    Citation: Malaria Journal 2006 5:16

    Content type: Methodology

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  9. Evaluate the frequency of failure of eight treatments for non-complicated malaria caused by Plasmodium falciparum in patients from Turbo (Urabá region), El Bagre and Zaragoza (Bajo Cauca region), applying the 199...

    Authors: Silvia Blair, Jaime Carmona-Fonseca, Juan G Piñeros, Alexandra Ríos, Tania Álvarez, Gonzalo Álvarez and Alberto Tobón

    Citation: Malaria Journal 2006 5:14

    Content type: Research

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  10. In the past two decades the east African highlands have experienced several major malaria epidemics. Currently there is a renewed interest in exploring the possibility of anopheline larval control through envi...

    Authors: Emmanuel Mushinzimana, Stephen Munga, Noboru Minakawa, Li Li, Chen-chieh Feng, Ling Bian, Uriel Kitron, Cindy Schmidt, Louisa Beck, Guofa Zhou, Andrew K Githeko and Guiyun Yan

    Citation: Malaria Journal 2006 5:13

    Content type: Research

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  11. The development of mosquito nets pre-treated with insecticide, Long Lasting Impregnated Nets (LLINs) that last the life span of the net, is a solution to the difficulty of the re-impregnation of conventional n...

    Authors: Roch K Dabiré, Abdoulaye Diabaté, Thierry Baldet, Léa Paré-Toé, Robert T Guiguemdé, Jean-Bosco Ouédraogo and Ole Skovmand

    Citation: Malaria Journal 2006 5:12

    Content type: Research

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  12. Ferroquine (FQ), or SSR97193, is a novel antimalarial drug currently in phase I clinical trials. FQ is a unique organometallic compound designed to overcome the chloroquine (CQ) resistance problem. FQ revealed...

    Authors: Wassim Daher, Christophe Biot, Thierry Fandeur, Helene Jouin, Lydie Pelinski, Eric Viscogliosi, Laurent Fraisse, Bruno Pradines, Jacques Brocard, Jamal Khalife and Daniel Dive

    Citation: Malaria Journal 2006 5:11

    Content type: Research

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  13. On the island of Bioko (Equatorial Guinea), insecticide-treated nets (ITNs) have been the main tool used to control malaria over the last 13 years. In 2004, started an indoor residual spraying (IRS) campaign t...

    Authors: Gema Pardo, Miguel Angel Descalzo, Laura Molina, Estefanía Custodio, Magdalena Lwanga, Catalina Mangue, Jaquelina Obono, Araceli Nchama, Jesús Roche, Agustín Benito and Jorge Cano

    Citation: Malaria Journal 2006 5:10

    Content type: Research

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  14. Integrated vector management (IVM) for malaria control requires ecological skills that are very scarce and rarely applied in Africa today. Partnerships between communities and academic ecologists can address t...

    Authors: W Richard Mukabana, Khadija Kannady, G Michael Kiama, Jasper N Ijumba, Evan M Mathenge, Ibrahim Kiche, Gamba Nkwengulila, Leonard Mboera, Deo Mtasiwa, Yoichi Yamagata, Ingeborg van Schayk, Bart GJ Knols, Steven W Lindsay, Marcia Caldas de Castro, Hassan Mshinda, Marcel Tanner…

    Citation: Malaria Journal 2006 5:9

    Content type: Opinion

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  15. Identification and better understanding of potential risk factors for malaria are important for targeted and cost-effective health interventions. Housing conditions have been suggested as one of the potential ...

    Authors: Yazoumé Yé, Moshe Hoshen, Valérie Louis, Simboro Séraphin, Issouf Traoré and Rainer Sauerborn

    Citation: Malaria Journal 2006 5:8

    Content type: Research

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  16. Analysis of malaria imported into eight European countries from the Indian sub-continent (ISC) (India, Pakistan, Bangladesh and Sri Lanka) led to a consensus statement on the use of chemoprophylaxis within Tro...

    Authors: RH Behrens, Z Bisoffi, A Björkman, J Gascon, C Hatz, T Jelinek, F Legros, N Mühlberger and P Voltersvik

    Citation: Malaria Journal 2006 5:7

    Content type: Commentary

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  17. Insecticide-treated bed nets (ITN) provide real hope for the reduction of the malaria burden across Africa. Understanding factors that determine access to ITN is crucial to debates surrounding the optimal deli...

    Authors: Abdisalan M Noor, Judith A Omumbo, Abdinasir A Amin, Dejan Zurovac and Robert W Snow

    Citation: Malaria Journal 2006 5:5

    Content type: Research

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  18. There is a need for improved targeting of antimalarial treatment if artemisinin combination therapy is to be successfully introduced in Africa. This study aimed to explore why malaria slides are requested and ...

    Authors: Hugh Reyburn, John Ruanda, Ombeni Mwerinde and Chris Drakeley

    Citation: Malaria Journal 2006 5:4

    Content type: Research

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  19. Malaria is by far the greatest cause of morbidity and mortality in Angola, being responsible for 50% of all outpatient attendance and around 22% of all hospital deaths, yet by 2003 only 2% of under-5s used ins...

    Authors: Nelson Cuamba, Kwang Shik Choi and Harold Townson

    Citation: Malaria Journal 2006 5:2

    Content type: Research

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  20. Evaluating copy numbers of given genes in Plasmodium falciparum parasites is of major importance for laboratory-based studies or epidemiological surveys. For instance, pfmdr1 gene amplification has been associate...

    Authors: Isabel D Ferreira, Virgílio E do Rosário and Pedro VL Cravo

    Citation: Malaria Journal 2006 5:1

    Content type: Methodology

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  21. Malaria afflicts 300–500 million people causing over 1 million deaths globally per year. The immunopathogenesis of malaria is mediated partly by co mplex cellular and immunomodulator interactions involving co-...

    Authors: Bismark Y Sarfo, Henry B Armah, Ikovwaiza Irune, Andrew A Adjei, Christine S Olver, Shailesh Singh, James W Lillard Jr and Jonathan K Stiles

    Citation: Malaria Journal 2005 4:63

    Content type: Research

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  22. In order to optimally prioritize and use public and private budgets for equitable malaria vector control, there is a need to determine the level and determinants of consumer demand for different vector control...

    Authors: Obinna Onwujekwe, El-Fatih Mohamed Malik, Sara Hassan Mustafa and Abraham Mnzava

    Citation: Malaria Journal 2005 4:62

    Content type: Research

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  23. Mutations in the haemoglobin beta-globin (HbB) and glucose-6-phosphate dehydrogenase (G6PD) genes cause widespread human genetic disorders such as sickle cell diseases and G6PD deficiency. In sub-Saharan Africa, ...

    Authors: Anders Enevold, Lasse S Vestergaard, John Lusingu, Chris J Drakeley, Martha M Lemnge, Thor G Theander, Ib C Bygbjerg and Michael Alifrangis

    Citation: Malaria Journal 2005 4:61

    Content type: Methodology

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  24. Alternative means of malaria control are urgently needed. Evaluating the effectiveness of measures that involve genetic manipulation of vector populations will be facilitated by identifying small, genetically ...

    Authors: Jonathan K Kayondo, Louis G Mukwaya, Aram Stump, Andrew P Michel, Mamadou B Coulibaly, Nora J Besansky and Frank H Collins

    Citation: Malaria Journal 2005 4:59

    Content type: Research

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  25. In Vietnam, a large proportion of all malaria cases and deaths occurs in the central mountainous and forested part of the country. Indeed, forest malaria, despite intensive control activities, is still a major...

    Authors: Annette Erhart, Ngo Duc Thang, Phan Van Ky, Ta Thi Tinh, Chantal Van Overmeir, Niko Speybroeck, Valerie Obsomer, Le Xuan Hung, Le Khanh Thuan, Marc Coosemans and Umberto D'alessandro

    Citation: Malaria Journal 2005 4:58

    Content type: Research

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  26. Abnormal motor posturing is often observed in children with cerebral malaria, but the aetiology and pathogenesis is poorly understood. This study examined the risk factors and outcome of posturing in Kenyan ch...

    Authors: Richard Idro, Godfrey Otieno, Steven White, Anderson Kahindi, Greg Fegan, Bernhards Ogutu, Sadik Mithwani, Kathryn Maitland, Brian GR Neville and Charles RJC Newton

    Citation: Malaria Journal 2005 4:57

    Content type: Research

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  27. Severe anaemia can develop in the aftermath of Plasmodium falciparum malaria because of protracted bone marrow suppression, possibly due to residual subpatent parasites.

    Authors: Marie Helleberg, Bamenla Q Goka, Bartholomew D Akanmori, George Obeng-Adjei, Onike Rodriques and Jorgen AL Kurtzhals

    Citation: Malaria Journal 2005 4:56

    Content type: Research

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  28. Systematic surveillance for resistant malaria shows high level of resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) across eastern and southern parts of Africa. This study assessed in vivo SP ...

    Authors: Kefas Mugittu, Salim Abdulla, Nicole Falk, Honorati Masanja, Ingrid Felger, Hassan Mshinda, Hans-Peter Beck and Blaise Genton

    Citation: Malaria Journal 2005 4:55

    Content type: Research

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  29. Acute malaria has been associated with a decreased antibody response to tetanus and diphtheria toxoids, meningococcal, salmonella, and Hib vaccines. Interest in giving malaria drug therapy and prevention at th...

    Authors: Jennifer B Rosen, Joel G Breman, Charles R Manclark, Bruce D Meade, William E Collins, Hans O Lobel, Pierre Saliou, Jacquelin M Roberts, Pierre Campaoré and Mark A Miller

    Citation: Malaria Journal 2005 4:53

    Content type: Research

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  30. Insecticide-treated nets (ITN) are an important method of preventing malaria. To remain effective, they need to be re-treated with pyrethroid insecticide at approximately yearly intervals. Systems for re-treat...

    Authors: Alison Yates, Raphael N'Guessan, Harparkash Kaur, Martin Akogbéto and Mark Rowland

    Citation: Malaria Journal 2005 4:52

    Content type: Research

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  31. Research is an essential tool in facing the challenges of scaling up interventions and improving access to services. As in many other countries, the translation of research evidence into drug policy action in ...

    Authors: Godfrey M Mubyazi and Miguel A Gonzalez-Block

    Citation: Malaria Journal 2005 4:51

    Content type: Case study

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  32. Malaria is a serious, sometimes fatal, disease caused by Plasmodium infection of human red blood cells. The host-parasite co-evolutionary processes are well understood by the association of coding variations such...

    Authors: Sonali Gaikwad, Richa Ashma, Nirbhay Kumar, Rajni Trivedi and VK Kashyap

    Citation: Malaria Journal 2005 4:50

    Content type: Opinion

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  33. The success of sterile or transgenic Anopheles for malaria control depends on their mating competitiveness within wild populations. Current evidence suggests that transgenic mosquitoes have reduced fitness. One m...

    Authors: Kija R Ng'habi, Bernadette John, Gamba Nkwengulila, Bart GJ Knols, Gerry F Killeen and Heather M Ferguson

    Citation: Malaria Journal 2005 4:49

    Content type: Research

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  34. Several studies conducted in areas of medium or low malaria transmission intensity have found associations between malaria immunity and plasma antibody levels to glutamate rich protein (GLURP). This study was ...

    Authors: John PA Lusingu, Lasse S Vestergaard, Michael Alifrangis, Bruno P Mmbando, Michael Theisen, Andrew Y Kitua, Martha M Lemnge and Thor G Theander

    Citation: Malaria Journal 2005 4:48

    Content type: Research

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  35. Malaria, both with or without convulsions, is a serious hardship for people living in endemic areas, especially in sub-Saharan Africa. Community references to malaria, however, may encompass other conditions, ...

    Authors: Collins K Ahorlu, Kwadwo A Koram, Cynthia Ahorlu, Don de Savigny and Mitchell G Weiss

    Citation: Malaria Journal 2005 4:47

    Content type: Research

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  36. The use of antimalarial drug combinations with artemisinin derivatives is recommended to overcome drug resistance in Plasmodium falciparum. The fixed combination of oral artemether-lumefantrine, an artemisinin co...

    Authors: Robert Hutagalung, Lucy Paiphun, Elizabeth A Ashley, Rose McGready, Alan Brockman, Kaw L Thwai, Pratap Singhasivanon, Thomas Jelinek, Nicholas J White and François H Nosten

    Citation: Malaria Journal 2005 4:46

    Content type: Research

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  37. Safe, effective and affordable drug combinations against falciparum malaria are urgently needed for the poor populations in malaria endemic countries. Methylene blue (MB) combined with chloroquine (CQ) has bee...

    Authors: Peter E Meissner, Germain Mandi, Steffen Witte, Boubacar Coulibaly, Ulrich Mansmann, Jens Rengelshausen, Wolfgang Schiek, Albrecht Jahn, Mamadou Sanon, Théophile Tapsoba, Ingeborg Walter-Sack, Gerd Mikus, Jürgen Burhenne, Klaus-Dieter Riedel, Heiner Schirmer, Bocar Kouyaté…

    Citation: Malaria Journal 2005 4:45

    Content type: Research

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  38. The use of transgenic mosquitoes with parasite inhibiting genes has been proposed as an integral strategy to control malaria transmission. However, release of exotic transgenic mosquitoes will bring in novel a...

    Authors: David M Menge, Tom Guda, Daibin Zhong, Aditi Pai, Goufa Zhou, John C Beier, Louis Gouagna and Guiyun Yan

    Citation: Malaria Journal 2005 4:44

    Content type: Research

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  39. Rapid urbanization in sub-Saharan Africa has a major impact on malaria epidemiology. While much is known about malaria in rural areas in Burkina Faso, the urban situation is less well understood.

    Authors: Shr-Jie Wang, Christian Lengeler, Thomas A Smith, Penelope Vounatsou, Diallo A Diadie, Xavier Pritroipa, Natalie Convelbo, Mathieu Kientga and Marcel Tanner

    Citation: Malaria Journal 2005 4:43

    Content type: Research

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  40. Both chloroquine (CQ) and sulfadoxine-pyrimethamine (SP) are failing drugs in much of sub-Saharan Africa. Previous findings suggest an association between resistance to CQ and to SP in vivo, in vitro, and on the ...

    Authors: Frank P Mockenhaupt, J Teun Bousema, Teunis A Eggelte, Stephan Ehrhardt, Rowland N Otchwemah, Robert W Sauerwein and Ulrich Bienzle

    Citation: Malaria Journal 2005 4:42

    Content type: Research

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  41. Early diagnosis and effective treatment with an appropriate drug form the main components of the World Health Organization's strategy to reduce malaria related mortality. The few available drugs might be safeg...

    Authors: Sakina B Elamin, Elfatih M Malik, Tarig Abdelgadir, Ammar H Khamiss, Mamoun M Mohammed, Elderderi S Ahmed and Ishag Adam

    Citation: Malaria Journal 2005 4:41

    Content type: Research

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  42. The rapid urban malaria appraisal (RUMA) methodology aims to provide a cost-effective tool to conduct rapid assessments of the malaria situation in urban sub-Saharan Africa and to improve the understanding of ...

    Authors: Shr-Jie Wang, Christian Lengeler, Thomas A Smith, Penelope Vounatsou, Guéladio Cissé, Diadie A Diallo, Martin Akogbeto, Deo Mtasiwa, Awash Teklehaimanot and Marcel Tanner

    Citation: Malaria Journal 2005 4:40

    Content type: Methodology

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  43. Although maternal anaemia often stems from malaria infection during pregnancy, its effects on foetal haemoglobin levels are not straightforward. Lower-than-expected cord haemoglobin values in malarious versus ...

    Authors: Elizabeth T Abrams, Jesse J Kwiek, Victor Mwapasa, Deborah D Kamwendo, Eyob Tadesse, Valentino M Lema, Malcolm E Molyneux, Stephen J Rogerson and Steven R Meshnick

    Citation: Malaria Journal 2005 4:39

    Content type: Research

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  44. IL-1β and IL-1RA levels are higher in the serum of cerebral malaria patients than in patients with mild malaria. Recently, the level of IL1B expression was reported to be influenced by a polymorphism in the promo...

    Authors: Jun Ohashi, Izumi Naka, Akihiro Doi, Jintana Patarapotikul, Hathairad Hananantachai, Noppadon Tangpukdee, Sornchai Looareesuwan and Katsushi Tokunaga

    Citation: Malaria Journal 2005 4:38

    Content type: Research

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