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  1. Post-transcriptional control of gene expression is suspected to play an important role in malaria parasites. In yeast and metazoans, part of the stress response is mediated through phosphorylation of eukaryoti...

    Authors: Clare Fennell, Shalon Babbitt, Ilaria Russo, Jonathan Wilkes, Lisa Ranford-Cartwright, Daniel E Goldberg and Christian Doerig
    Citation: Malaria Journal 2009 8:99
  2. The magnetic properties of Plasmodium-infected erythrocytes have been exploited for different clinical and research purposes. A recent study in a rural clinical setting in Papua New Guinea has demonstrated that P...

    Authors: Stephan Karl, Timothy ME Davis and Tim G St-Pierre
    Citation: Malaria Journal 2009 8:98
  3. Mannose binding lectin (MBL) has an important role in the activation of the complement system and opsonization of pathogenic microorganisms. Frequent polymorphisms found in the MBL2 gene affect the concentration ...

    Authors: Angelica BW Boldt, Iara J Messias-Reason, Bertrand Lell, Saadou Issifou, Maria Lucia Alves Pedroso, Peter G Kremsner and Jürgen FJ Kun
    Citation: Malaria Journal 2009 8:97
  4. In the Philippines, malaria morbidity and mortality have decreased since the 1990s by effective malaria control. Several epidemiological surveys have been performed in the country, but the characteristics of the

    Authors: Moritoshi Iwagami, Pilarita T Rivera, Elena A Villacorte, Aleyla D Escueta, Toshimitsu Hatabu, Shin-ichiro Kawazu, Toshiyuki Hayakawa, Kazuyuki Tanabe and Shigeyuki Kano
    Citation: Malaria Journal 2009 8:96
  5. Malaria is one of the main motives for outpatient consultation and hospitalization in Mauritania. However, its incidence remains unclear because of diagnostic problems and insufficient epidemiological data.

    Authors: Khadijetou Mint Lekweiry, Mohamed Ould Abdallahi, Hâmpaté Ba, Céline Arnathau, Patrick Durand, Jean-François Trape and Ali Ould Mohamed Salem
    Citation: Malaria Journal 2009 8:92
  6. Severe malaria anaemia in the semi-immune individuals in the holo-endemic area has been observed to occur at low parasite density with individual variation in the responses. Thus the following has been thought...

    Authors: Gideon Kofi Helegbe, Nguyen T Huy, Tetsuo Yanagi, Mohammed N Shuaibu, Akiko Yamazaki, Mihoko Kikuchi, Michio Yasunami and Kenji Hirayama
    Citation: Malaria Journal 2009 8:91
  7. Two malaria rapid diagnostic tests were evaluated in a travel clinic setting: the SD FK50 Malaria Ag Plasmodium falciparum test (a two-band test) and the SD FK60 Malaria Ag P. falciparum/Pan test (a three-band te...

    Authors: Mirna Van der Palen, Philippe Gillet, Emmanuel Bottieau, Lieselotte Cnops, Marjan Van Esbroeck and Jan Jacobs
    Citation: Malaria Journal 2009 8:90
  8. An assessment of the correlation between anti-malarial treatment outcome and molecular markers would improve the early detection and monitoring of drug resistance by Plasmodium falciparum. The purpose of this sys...

    Authors: Stéphane Picot, Piero Olliaro, Frédérique de Monbrison, Anne-Lise Bienvenu, Ric N Price and Pascal Ringwald
    Citation: Malaria Journal 2009 8:89
  9. Despite continuous efforts of the international community to reduce the impact of malaria on developing countries, no significant progress has been made in the recent years and the discovery of new drugs is mo...

    Authors: Vinod Kasam, Jean Salzemann, Marli Botha, Ana Dacosta, Gianluca Degliesposti, Raul Isea, Doman Kim, Astrid Maass, Colin Kenyon, Giulio Rastelli, Martin Hofmann-Apitius and Vincent Breton
    Citation: Malaria Journal 2009 8:88
  10. Several strategies are currently deployed in many countries in the tropics to strengthen malaria control toward malaria elimination. To measure the impact of any intervention, there is a need to detect malaria...

    Authors: Nicolas Steenkeste, Sandra Incardona, Sophy Chy, Linda Duval, Marie-Thérèse Ekala, Pharath Lim, Sean Hewitt, Tho Sochantha, Doung Socheat, Christophe Rogier, Odile Mercereau-Puijalon, Thierry Fandeur and Frédéric Ariey
    Citation: Malaria Journal 2009 8:86
  11. As insecticide resistance may jeopardize the successful malaria control programmes in the Mekong region, a large investigation was previously conducted in the Mekong countries to assess the susceptibility of t...

    Authors: Katrijn Verhaeghen, Wim Van Bortel, Ho Dinh Trung, Tho Sochantha and Marc Coosemans
    Citation: Malaria Journal 2009 8:84
  12. In the rural zone of Niakhar in Senegal, the first therapeutic failures for chloroquine (CQ) were observed in 1992. In 2003, the national policy regarding first-line treatment of uncomplicated malaria was modi...

    Authors: Aline Munier, Aldiouma Diallo, Michel Cot, Ousmane Ndiaye, Pascal Arduin and Jean-Philippe Chippaux
    Citation: Malaria Journal 2009 8:83
  13. Malaria vector sampling is the best method for understanding the vector dynamics and infectivity; thus, disease transmission seasonality can be established. There is a need to protecting humans involved in the...

    Authors: Eliningaya J Kweka, Beda J Mwang'onde, Epiphania Kimaro, Shandala Msangi, Charles P Massenga and Aneth M Mahande
    Citation: Malaria Journal 2009 8:82
  14. Malaria is a major public health problem in Ghana. The current strategy of the National Malaria Control Programme is based on effective case management and the use of insecticide treated bed nets among vulnera...

    Authors: Francis Anto, Victor Asoala, Thomas Anyorigiya, Abraham Oduro, Martin Adjuik, Seth Owusu-Agyei, Dominic Dery, Langbong Bimi and Abraham Hodgson
    Citation: Malaria Journal 2009 8:81
  15. Pyronaridine, a Mannich base anti-malarial with high efficacy against drug resistant Plasmodium falciparum, is currently evaluated as a fixed dose combination with artesunate for the treatment of uncomplicated ma...

    Authors: Florian Kurth, Peter Pongratz, Sabine Bélard, Benjamin Mordmüller, Peter G Kremsner and Michael Ramharter
    Citation: Malaria Journal 2009 8:79
  16. Genotyping of Plasmodium falciparum based on PCR amplification of the polymorphic genes encoding the merozoite surface proteins 1 and 2 (msp1 and msp2) is well established in the field of malaria research to dete...

    Authors: Anne Liljander, Lisa Wiklund, Nicole Falk, Margaret Kweku, Andreas Mårtensson, Ingrid Felger and Anna Färnert
    Citation: Malaria Journal 2009 8:78
  17. Distribution of insecticide-treated nets (ITNs) has recently been incorporated into comprehensive care strategies for HIV-positive people in malaria-endemic areas. WHO now recommends free or low-cost distribut...

    Authors: Lauren Cohee, Lisa A Mills, Joseph Kagaayi, Ilana Jacobs, Ronald Galiwango, James Ludigo, Joseph Ssekasanvu and Steven J Reynolds
    Citation: Malaria Journal 2009 8:76
  18. Anopheles gambiae sensu stricto, one of the principal vectors of malaria, has been divided into two subspecific groups, known as the M and S molecular forms. Recent studies suggest that the M form found in Camero...

    Authors: Yoosook Lee, Anthony J Cornel, Claudio R Meneses, Abdrahamane Fofana, Aurélie G Andrianarivo, Rory D McAbee, Etienne Fondjo, Sekou F Traoré and Gregory C Lanzaro
    Citation: Malaria Journal 2009 8:75
  19. Protection against clinical malaria episodes is acquired slowly after frequent exposure to malaria parasites. This is reflected by a decrease with increasing age in both parasite density and incidence of clini...

    Authors: Samuel Mabunda, John J Aponte, Armindo Tiago and Pedro Alonso
    Citation: Malaria Journal 2009 8:74
  20. Human infections with Plasmodium knowlesi, a simian malaria parasite, are more common than previously thought. They have been detected by molecular detection methods in various countries in Southeast Asia, where ...

    Authors: Kim-Sung Lee, Janet Cox-Singh and Balbir Singh
    Citation: Malaria Journal 2009 8:73
  21. In non-endemic areas, malaria is rare and locally acquired infections, particularly with Plasmodium falciparum, are exceptional events. The diagnosis is, therefore, likely to be delayed or missed in patients with...

    Authors: Thomas Zoller, Torsten J Naucke, Jürgen May, Bodo Hoffmeister, Holger Flick, Christopher J Williams, Christina Frank, Frank Bergmann, Norbert Suttorp and Frank P Mockenhaupt
    Citation: Malaria Journal 2009 8:71
  22. Insecticide resistance is a rapid and recent evolutionary phenomenon with serious economic and public health implications. In the mosquito Anopheles gambiae s.s., main vector of malaria, resistance to organophosp...

    Authors: Luc Djogbénou, Pierrick Labbé, Fabrice Chandre, Nicole Pasteur and Mylène Weill
    Citation: Malaria Journal 2009 8:70
  23. The P-loop NTPases constitute one of the largest groups of globular protein domains that play highly diverse functional roles in most of the organisms. Even with the availability of nearly 300 different Hidden...

    Authors: Deepti Gangwar, Mridul K Kalita, Dinesh Gupta, Virander S Chauhan and Asif Mohmmed
    Citation: Malaria Journal 2009 8:69
  24. Mpumalanga Province, South Africa is a low malaria transmission area that is subject to malaria epidemics. SaTScan methodology was used by the malaria control programme to detect local malaria clusters to assi...

    Authors: Marlize Coleman, Michael Coleman, Aaron M Mabuza, Gerdalize Kok, Maureen Coetzee and David N Durrheim
    Citation: Malaria Journal 2009 8:68
  25. Placental malaria is typified by selective clustering of Plasmodium falciparum in the intervillous blood spaces of the placenta. Sequestration of malaria parasite in the human placenta is mediated by interactions...

    Authors: Jasmita Gill, Chetan E Chitnis and Amit Sharma
    Citation: Malaria Journal 2009 8:67
  26. In Uganda, like in many other countries traditionally viewed as harbouring very high malaria transmission, the norm has been to recommend that febrile episodes are diagnosed as malaria. In this study, the poli...

    Authors: Joan Nankabirwa, Dejan Zurovac, Julius N Njogu, John B Rwakimari, Helen Counihan, Robert W Snow and James K Tibenderana
    Citation: Malaria Journal 2009 8:66
  27. There is no clear consensus on the most sustainable and effective distribution strategy for insecticide treated bed nets (ITNs). Tanzania has been a leader in social marketing but it is still not clear if this...

    Authors: Jubilate Bernard, George Mtove, Renata Mandike, Frank Mtei, Caroline Maxwell and Hugh Reyburn
    Citation: Malaria Journal 2009 8:65
  28. Use of insecticide-treated nets (ITNs) continues to offer potential strategy for malaria prevention in endemic areas. However their effectiveness, sustainability and massive scale up remain a factor of socio-e...

    Authors: Peter N Ng'ang'a, Gayathri Jayasinghe, Violet Kimani, Josephat Shililu, Charity Kabutha, Lucy Kabuage, John Githure and Clifford Mutero
    Citation: Malaria Journal 2009 8:64
  29. The efficacy of artemisinin-based combination therapy has already been demonstrated in a number of studies all over the world, and some of them can be regarded as comparably effective. Ease of administration o...

    Authors: Issaka Sagara, Stephen Rulisa, Wilfred Mbacham, Ishag Adam, Kourane Sissoko, Hamma Maiga, Oumar B Traore, Niawanlou Dara, Yahia T Dicko, Alassane Dicko, Abdoulaye Djimdé, F Herwig Jansen and Ogobara K Doumbo
    Citation: Malaria Journal 2009 8:63
  30. Ideally larval control activities should be targeted at sites that generate the most adult vectors, thereby reducing operational costs. Despite the plethora of potential mosquito breeding sites found in the fl...

    Authors: Ulrike Fillinger, Heleen Sombroek, Silas Majambere, Emiel van Loon, Willem Takken and Steven W Lindsay
    Citation: Malaria Journal 2009 8:62
  31. The risk of Plasmodium falciparum infection is variable over space and time and this variability is related to environmental variability. Environmental factors affect the biological cycle of both vector and paras...

    Authors: Jean Gaudart, Ousmane Touré, Nadine Dessay, A lassane Dicko, Stéphane Ranque, Loic Forest, Jacques Demongeot and Ogobara K Doumbo
    Citation: Malaria Journal 2009 8:61
  32. Anopheles (Kerteszia) cruzii was the most important vector of human malaria in southern Brazil between 1930–1960. Nowadays it is still considered an important Plasmodium spp. vector in southern and south-eastern ...

    Authors: Luísa DP Rona, Carlos J Carvalho-Pinto, Carla Gentile, Edmundo C Grisard and Alexandre A Peixoto
    Citation: Malaria Journal 2009 8:60
  33. In response to chloroquine (CQ) resistance, the policy for the first-line treatment of uncomplicated malaria in the Democratic Republic of East Timor (DRET) was changed in early 2000. The combination of sulpha...

    Authors: Afonso de Almeida, Ana Paula Arez, Pedro VL Cravo and Virgílio E do Rosário
    Citation: Malaria Journal 2009 8:59
  34. Artemisinin-based combination therapy (ACT) is recommended as a means of prolonging the effectiveness of first-line malaria treatment regimens. Different brands of mefloquine (MQ) have been reported to be non-...

    Authors: Julie Gutman, Michael Green, Salomon Durand, Ofelia Villalva Rojas, Babita Ganguly, Wilmer Marquiño Quezada, Gregory C Utz, Laurence Slutsker, Trenton K Ruebush II and David J Bacon
    Citation: Malaria Journal 2009 8:58
  35. Historically, environmental management has brought important achievements in malaria control and overall improvements of health conditions. Currently, however, implementation is often considered not to be cost...

    Authors: Marcia C Castro, Atsuko Tsuruta, Shogo Kanamori, Khadija Kannady and Sixbert Mkude
    Citation: Malaria Journal 2009 8:57
  36. For companies operating in malaria endemic countries, malaria represents a substantial risk to workers and their dependants, and can lead to significantly reduced worker productivity. This study provides an ov...

    Authors: Bianca Pluess, Ivo Mueller, Damien Levi, Graham King, Thomas A Smith and Christian Lengeler
    Citation: Malaria Journal 2009 8:56
  37. There are increasing reports of severe clinical cases exclusively associated with Plasmodium vivax infections. Notably, this severity has been recently suggested to be associated with chloroquine resistance.

    Authors: Carmen Fernández-Becerra, Maria Jesús Pinazo, Ana González, Pedro L Alonso, Hernando A del Portillo and Joaquim Gascón
    Citation: Malaria Journal 2009 8:55
  38. To date all efforts to develop a malaria vaccine have failed, reflecting the still fragmentary knowledge about protective mechanisms against malaria. In order to evaluate if vaccination changes responses of th...

    Authors: Jürgen Krücken, Denis Delić, Heike Pauen, Anna Wojtalla, Manal El-Khadragy, Mohamed A Dkhil, Horst Mossmann and Frank Wunderlich
    Citation: Malaria Journal 2009 8:54
  39. GIMAP (GTPase of the immunity-associated protein family) proteins are a family of putative GTPases believed to be regulators of cell death in lymphomyeloid cells. GIMAP1 was the first reported member of this g...

    Authors: Amy Saunders, Tracey Lamb, John Pascall, Amanda Hutchings, Carine Dion, Christine Carter, Lucy Hepburn, Jean Langhorne and Geoffrey W Butcher
    Citation: Malaria Journal 2009 8:53
  40. Artemisinin combination therapy (ACT) has been widely adopted as first-line treatment for uncomplicated falciparum malaria. In Uganda, amodiaquine plus artesunate (AQ+AS), is the alternative first-line regimen...

    Authors: Muhammad Ntale, Celestino Obua, Jackson Mukonzo, Margarita Mahindi, Lars L Gustafsson, Olof Beck and Jasper W Ogwal-Okeng
    Citation: Malaria Journal 2009 8:52
  41. While insecticide-treated nets (ITNs) are a recognized effective method for preventing malaria, there has been an extensive debate in recent years about the best large-scale implementation strategy. Implementa...

    Authors: Joshua O Yukich, Mehari Zerom, Tewolde Ghebremeskel, Fabrizio Tediosi and Christian Lengeler
    Citation: Malaria Journal 2009 8:51

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