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  1. Malaria remains a major cause of morbidity and mortality among children in Africa. There is inadequate information regarding malaria transmission-intensity in some of the worst-affected parts of sub-Saharan Af...

    Authors: Usman Nasir Nakakana, Ismaila Ahmed Mohammed, B. O. Onankpa, Ridwan M. Jega and Nma Muhammad Jiya

    Citation: Malaria Journal 2020 19:149

    Content type: Research

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  2. A previous study reported that the malaria parasite Plasmodium falciparum enters an altered growth state upon extracellular withdrawal of the essential amino acid isoleucine. Parasites slowed transit through the ...

    Authors: Kyle Jarrod McLean and Marcelo Jacobs-Lorena

    Citation: Malaria Journal 2020 19:147

    Content type: Research

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  3. Insecticide-treated nets (ITNs) are losing efficacy against pyrethroid-resistant malaria vector populations throughout Africa. Safeguarding bed net efficacy, vital for effective malaria control, requires great...

    Authors: Angela Hughes, Geraldine M. Foster, Amy Guy, Agnes Matope, Mayumi Abe, David Towers and Philip J. McCall

    Citation: Malaria Journal 2020 19:140

    Content type: Research

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  4. Dissolution of artemether (ART) and lumefantrine (LUM) active pharmaceutical ingredients (APIs) in fixed dose combination (FDC) ART/LUM tablets is one of the critical quality attributes. Thus, the verification...

    Authors: Sileshi Belew, Sultan Suleman, Markos Duguma, Henok Teshome, Evelien Wynendaele, Luc Duchateau and Bart De Spiegeleer

    Citation: Malaria Journal 2020 19:139

    Content type: Research

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  5. Seasonal malaria chemoprevention (SMC) is a new strategy to prevent malaria in children under 5 years old. It has been recommended by the World Health Organization since 2012 in malaria-endemic areas with seas...

    Authors: Drissa Konaté, Sory I. Diawara, Mahamoudou Touré, Seidina A. S. Diakité, Agnès Guindo, Karim Traoré, Ayouba Diarra, Bourama Keita, Sibe Thiam, Moussa Keita, Ibrahim Sissoko, Nafomon Sogoba, Sékou F. Traoré, Donald J. Krogtad, Seydou Doumbia and Mahamadou Diakité

    Citation: Malaria Journal 2020 19:137

    Content type: Research

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  6. Since the National Malaria Elimination Action Plan was launched in China in 2010, local malaria transmission has decreased rapidly. Zero indigenous cases were reported since 2017. However, after 2010, the prop...

    Authors: Mei-hua Zhang, Sui Xu, Ya-ping Gu, Yao-bao Liu, Hong Lin, Chao-yong Xie, Yue-e Chen, Jian-feng Chen, Hua-yun Zhou, Leonard Ortega, Guo-ding Zhu and Jun Cao

    Citation: Malaria Journal 2020 19:136

    Content type: Case study

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  7. Owing to the large amount of host DNA in clinical samples, generation of high-quality Plasmodium falciparum whole genome sequencing (WGS) data requires enrichment for parasite DNA. Enrichment is often achieved by...

    Authors: Zalak Shah, Matthew Adams, Kara A. Moser, Biraj Shrestha, Emily M. Stucke, Miriam K. Laufer, David Serre, Joana C. Silva and Shannon Takala-Harrison

    Citation: Malaria Journal 2020 19:135

    Content type: Methodology

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  8. In 2006, the Senegalese National Malaria Control Programme recommended artemisinin-based combination therapy (ACT) with artemether–lumefantrine as the first-line treatment for uncomplicated Plasmodium falciparum ...

    Authors: Amy Gaye, Mouhamad Sy, Tolla Ndiaye, Katherine J. Siddle, Daniel J. Park, Awa B. Deme, Aminata Mbaye, Baba Dieye, Yaye Die Ndiaye, Daniel E. Neafsey, Angela Early, Timothy Farrell, Mamadou Samb Yade, Mamadou Alpha Diallo, Khadim Diongue, Amy Bei…

    Citation: Malaria Journal 2020 19:134

    Content type: Research

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  9. Conceptualizing gender dynamics and ways of bridging entrenched gender roles will contribute to better health promotion, policy and planning. Such processes are explored in relation to malaria in Mozambique.

    Authors: Zoe Jane-Lara Hildon, Maria Escorcio-Ymayo, Rose Zulliger, Rosario Arias de Aramburú, Nan Lewicky, Hunter Harig, Jose Braz Chidassicua, Carol Underwood, Liliana Pinto and Maria Elena Figueroa

    Citation: Malaria Journal 2020 19:133

    Content type: Research

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  10. During the erythrocytic cycle, Plasmodium falciparum malaria parasites express P. falciparum Erythrocyte Membrane Protein 1 (PfEMP1) that anchor the infected erythrocytes (IE) to the vascular lining of the host. ...

    Authors: Charlotte Harmsen, Louise Turner, Susan Thrane, Adam F. Sander, Thor G. Theander and Thomas Lavstsen

    Citation: Malaria Journal 2020 19:132

    Content type: Research

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  11. China launched the National Malaria Elimination Programme (NMEP) in 2010 and set the goal that all health facilities should be able to diagnose malaria. Additionally, hospitals at all levels could treat malari...

    Authors: Gang Li, Donglan Zhang, Zhuo Chen, Da Feng, Xiaoyu Chen, Shangfeng Tang, Heejung Son, Zhenhua Wang, Yuanhang Xi and Zhanchun Feng

    Citation: Malaria Journal 2020 19:131

    Content type: Research

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  12. Several refugee settlements in Bangladesh have provided housing and medical care for the forcibly-displaced Myanmar nationals (FDMN, also known as Rohingya) population. The identification of malaria infection ...

    Authors: Austin Lu, Olivia Cote, Silvia D. Dimitrova, Gretchen Cooley, A. Alamgir, M. Salim Uzzaman, Meerjady Sabrina Flora, Yulia Widiati, Mohammad Saifuddin Akhtar, Maya Vandenent, Daniel C. Ehlman, Sarah D. Bennett, Leora R. Feldstein and Eric Rogier

    Citation: Malaria Journal 2020 19:130

    Content type: Research

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  13. The World Health Organization (WHO) recommends parasite-based diagnosis of malaria. In recent years, there has been surge in the use of various kinds of nucleic-acid amplification based tests (NAATs) for detec...

    Authors: Jane A. Cunningham, Rebecca M. Thomson, Sean C. Murphy, Maria de la Paz Ade, Xavier C. Ding, Sandra Incardona, Eric Legrand, Naomi W. Lucchi, Didier Menard, Samuel L. Nsobya, Agatha C. Saez, Peter L. Chiodini and Jaya Shrivastava

    Citation: Malaria Journal 2020 19:129

    Content type: Research

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  14. Malaria control using long-lasting insecticidal nets (LLINs) and indoor residual spraying of insecticide (IRS) has been associated with reduced transmission throughout Africa. However, the impact of transmissi...

    Authors: Simon P. Kigozi, Ruth N. Kigozi, Adrienne Epstein, Arthur Mpimbaza, Asadu Sserwanga, Adoke Yeka, Joaniter I. Nankabirwa, Katherine Halliday, Rachel L. Pullan, Damian Rutazaana, Catherine M. Sebuguzi, Jimmy Opigo, Moses R. Kamya, Sarah G. Staedke, Grant Dorsey, Bryan Greenhouse…

    Citation: Malaria Journal 2020 19:128

    Content type: Research

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  15. There is an urgent need for an effective vaccine to control and eradicate malaria, one of the most serious global infectious diseases. Plasmodium merozoite surface protein 4 (MSP4) has been listed as a blood-stag...

    Authors: Juliette Uwase, Ruilin Chu, Kokouvi Kassegne, Yao Lei, Feihu Shen, Haitian Fu, Yifan Sun, Yinghua Xuan, Jun Cao and Yang Cheng

    Citation: Malaria Journal 2020 19:126

    Content type: Research

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  16. Despite huge investments and implementation of effective interventions for malaria, progress has stalled, with transmission being increasingly localized among difficult-to-reach populations and outdoor-biting ...

    Authors: Roly Gosling, John Chimumbwa, Petrina Uusiku, Sara Rossi, Henry Ntuku, Kelly Harvard, Chris White, Allison Tatarsky, Daniel Chandramohan and Ingrid Chen

    Citation: Malaria Journal 2020 19:125

    Content type: Opinion

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  17. Following guidance from the US President’s Malaria Initiative, durability monitoring of DawaPlus® 2.0 brand of long-lasting insecticidal net (LLIN) distributed during the 2015/16 mass campaign was set up in three...

    Authors: Emmanuel Obi, Festus Okoh, Sean Blaufuss, Bolanle Olapeju, Joel Akilah, Okefu Oyale Okoko, Abidemi Okechukwu, Mark Maire, Kehinda Popoola, Muhammad Abdullahi Yahaya, Chigozie Jesse Uneke, Samson Awolola, Olivier Pigeon, Stella Babalola, Hannah Koenker and Albert Kilian

    Citation: Malaria Journal 2020 19:124

    Content type: Research

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  18. Malaria surveillance requires powerful tools and strategies to achieve malaria elimination. Rapid diagnostic tests for malaria (RDTs) are easily deployed on a large scale and are helpful sources of parasite DN...

    Authors: Kiswendsida Thierry Guiguemde, Yakou Dieye, Aminata Collé Lô, Magatte Ndiaye, Aminata Lam, Isaac Akhénaton Manga, Gnagna Dieng Sow, Moussa Diop, Tamba Souané, Marie Pièrre Diouf, Roger Clément Kouly Tine and Babacar Faye

    Citation: Malaria Journal 2020 19:123

    Content type: Research

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  19. Please note, following publication of the original article [1], the authors have advised of three errors that are present in the published article.

    Authors: Sonal Gupta, Juveria Khan, Priti Kumari, Chintam Narayana, R. Ayana, Malabika Chakrabarti, Ram Sagar and Shailja Singh

    Citation: Malaria Journal 2020 19:122

    Content type: Correction

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    The original article was published in Malaria Journal 2019 18:346

  20. The loss of chloroquine (CQ) effectiveness has led to its withdrawal from national policies as a first-line treatment for uncomplicated malaria in several endemic countries, such as the Democratic Republic of ...

    Authors: Doudou M. Yobi, Nadine K. Kayiba, Dieudonné M. Mvumbi, Raphael Boreux, Pius Z. Kabututu, Hippolyte N. T. Situakibanza, Joris L. Likwela, Patrick De Mol, Emile W. Okitolonda, Niko Speybroeck, Georges L. Mvumbi and Marie-Pierre Hayette

    Citation: Malaria Journal 2020 19:121

    Content type: Research

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  21. The Ministry of Health, Ghana, in accordance with global policy, recommends that all suspected malaria cases be confirmed parasitologically before treatment. Not all clinicians, however, base their treatment o...

    Authors: Jonathan Mawutor Gmanyami, Asiwome Ameko, Saviour Selase Ahiafe, Samuel Adolf Bosoka, Margaret Kweku and Evelyn Korkor Ansah

    Citation: Malaria Journal 2020 19:120

    Content type: Research

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  22. Drug safety assessments in clinical trials present unique analytical challenges. Some of these include adjusting for individual follow-up time, repeated measurements of multiple outcomes and missing data among...

    Authors: Noel Patson, Mavuto Mukaka, Kennedy N. Otwombe, Lawrence Kazembe, Don P. Mathanga, Victor Mwapasa, Alinune N. Kabaghe, Marinus J. C. Eijkemans, Miriam K. Laufer and Tobias Chirwa

    Citation: Malaria Journal 2020 19:119

    Content type: Research

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  23. Seasonal malaria chemoprevention (SMC) relies on community health workers to distribute drugs. This study assessed: (1) the capacity of community-based distributors (CBDs) at the start and end of a campaign an...

    Authors: Abel Bicaba, Luc Serme, Gaël Chetaille, Gountante Kombate, Alice Bila and Slim Haddad

    Citation: Malaria Journal 2020 19:118

    Content type: Research

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  24. Ongoing efforts to fight Plasmodium falciparum malaria has reduced malaria in many areas, but new tools are needed to monitor further progress, including indicators of decreasing exposure to parasite infection. S...

    Authors: Marie-Louise Varela, David Koffi, Michael White, Makhtar Niang, Babacar Mbengue, Fatoumata Diene Sarr, André Offianan Touré and Ronald Perraut

    Citation: Malaria Journal 2020 19:117

    Content type: Research

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  25. Between 1999 and 2008 Russia experienced a flare-up of transmission of vivax malaria following its massive importation with more than 500 autochthonous cases in European Russia, the Moscow region being the mos...

    Authors: Varvara A. Mironova, Natalia V. Shartova, Andrei E. Beljaev, Mikhail I. Varentsov, Fedor I. Korennoy and Mikhail Y. Grishchenko

    Citation: Malaria Journal 2020 19:116

    Content type: Research

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  26. Malaria is a major public health problem in Cameroon. The study of the genetic diversity within parasite population is essential for understanding the mechanism underlying malaria pathology and to determine pa...

    Authors: Theresia Njuabe Metoh, Jun-Hu Chen, Philip Fon-Gah, Xia Zhou, Roger Moyou-Somo and Xiao-Nong Zhou

    Citation: Malaria Journal 2020 19:115

    Content type: Research

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  27. Malaria mortality and morbidity have decreased in recent years. Malaria elimination (ME) and effective efforts to achieve ME is one of the most important priorities for health systems in countries in the elimi...

    Authors: Hosein Azizi, Elham Davtalab-Esmaeili, Mostafa Farahbakhsh, Maryam Zeinolabedini, Yagoub Mirzaei and Mohammad Mirzapour

    Citation: Malaria Journal 2020 19:114

    Content type: Research

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  28. New strategies are needed to reduce the incidence of malaria, and promising approaches include the development of vaccines and monoclonal antibodies (mAbs) that target the circumsporozoite protein (CSP). To se...

    Authors: Rama Raghunandan, Bryan T. Mayer, Yevel Flores-Garcia, Monica W. Gerber, Raphael Gottardo, Hugo Jhun, Sonia M. Herrera, Daniel W. Perez-Ramos, Emily Locke, C. Richter King and Fidel Zavala

    Citation: Malaria Journal 2020 19:113

    Content type: Research

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  29. Malaria is one of the main public health challenges in Ethiopia that hinder the productivity and development of the country. In 2018, Ethiopia is on track to minimize the incidence of malaria by 40% as per its...

    Authors: Absra Solomon, Daniel Kahase and Mihret Alemayehu

    Citation: Malaria Journal 2020 19:112

    Content type: Research

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  30. Tafenoquine is an 8-aminoquinoline anti-malarial drug recently approved as a single-dose (300 mg) therapy for Plasmodium vivax relapse prevention, when co-administered with 3-days of chloroquine or other blood sc...

    Authors: Stephan Duparc, Stephan Chalon, Scott Miller, Naomi Richardson and Stephen Toovey

    Citation: Malaria Journal 2020 19:111

    Content type: Review

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  31. Long-lasting insecticidal nets (LLINs) are the most sustainable and effective malaria control tool currently available. Global targets are for 80% of the population living in malaria endemic areas to have acce...

    Authors: Jeremiah J. Musa, Sarah J. Moore, Jason Moore, Emmanuel Mbuba, Edgar Mbeyela, Dickson Kobe, Johnson K. Swai and Olukayode G. Odufuwa

    Citation: Malaria Journal 2020 19:110

    Content type: Research

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  32. Residents of malaria-endemic communities spend several hours outdoors performing different activities, e.g. cooking, story-telling or eating, thereby exposing themselves to potentially-infectious mosquitoes. T...

    Authors: John P. Masalu, Marceline Finda, Gerry F. Killeen, Halfan S. Ngowo, Polius G. Pinda and Fredros O. Okumu

    Citation: Malaria Journal 2020 19:109

    Content type: Research

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  33. Ethiopia has set a goal for malaria elimination by 2030. Low parasite density infections may go undetected by conventional diagnostic methods (microscopy and rapid diagnostic tests) and their contribution to m...

    Authors: Ashenafi Assefa, Ahmed Ali Ahmed, Wakgari Deressa, G. Glenn Wilson, Amha Kebede, Hussein Mohammed, Maruon Sassine, Mebrahtom Haile, Dereje Dilu, Hiwot Teka, Matthew W. Murphy, Sheila Sergent, Eric Rogier, Zhou Zhiyong, Brian S. Wakeman, Chris Drakeley…

    Citation: Malaria Journal 2020 19:108

    Content type: Research

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  34. Resistance to anti-malarials is a major threat to the control and elimination of malaria. Sulfadoxine–pyrimethamine (SP) anti-malarial treatment was used as a national policy for treatment of uncomplicated fal...

    Authors: Rungniran Sugaram, Kanokon Suwannasin, Chanon Kunasol, Vivek Bhakta Mathema, Nicholas P. J. Day, Prayuth Sudathip, Preecha Prempree, Arjen M. Dondorp and Mallika Imwong

    Citation: Malaria Journal 2020 19:107

    Content type: Research

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  35. Insecticide-treated nets (ITNs) are one of the most cost-effective measures for preventing malaria. The World Health Organization recommends both large-scale mass distribution campaigns and continuous distribu...

    Authors: Sara S. Scates, Timothy P. Finn, Janna Wisniewski, David Dadi, Renata Mandike, Mwinyi Khamis, George Greer, Naomi Serbantez, Sylvester Segbaya, Prince Owusu, Jules Mihigo, Lilia Gerberg, Angela Acosta, Hannah Koenker and Joshua Yukich

    Citation: Malaria Journal 2020 19:105

    Content type: Research

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  36. Timor Leste has made remarkable progress from malaria control to malaria elimination in a span of 10 years during which organized malaria control efforts were instituted. The good practices and possible factor...

    Authors: A. M. G. Manel Yapabandara, Maria do Rosario de Fatima Mota, Raul Sarmento, Johanes don Bosco and Rajitha Wickremasinghe

    Citation: Malaria Journal 2020 19:104

    Content type: Research

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  37. Seasonal malaria chemoprevention is widely implemented in Sahel and sub-Sahel countries in Africa. Few studies have assessed the impact of the SMC on hospital admission and death when it is implemented in the ...

    Authors: Djibrilla Issiaka, Amadou Barry, Tiangoua Traore, Boubacar Diarra, David Cook, Mohamed Keita, Issaka Sagara, Patrick Duffy, Michal Fried and Alassane Dicko

    Citation: Malaria Journal 2020 19:103

    Content type: Research

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  38. More than ever, it is crucial to make the best use of existing country data, and analytical tools for developing malaria control strategies as the heterogeneity in malaria risk within countries is increasing, ...

    Authors: Manuela Runge, Fabrizio Molteni, Renata Mandike, Robert W. Snow, Christian Lengeler, Ally Mohamed and Emilie Pothin

    Citation: Malaria Journal 2020 19:101

    Content type: Case study

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  39. Growing concerns about the waning efficacy of IPTp-SP warrants continuous monitoring and evaluation. This study determined coverage of IPTp-SP and compared the effectiveness of the 3-dose to 2-dose regimen on ...

    Authors: Judith K. Anchang-Kimbi, Laken N. Kalaji, Harry F. Mbacham, Godlove B. Wepnje, Tobias O. Apinjoh, Irene U. Ngole Sumbele, Jodie Dionne-Odom, Alan T. N. Tita and Eric A. Achidi

    Citation: Malaria Journal 2020 19:100

    Content type: Research

    Published on:

  40. The World Health Organization (WHO) recommends rapid diagnostic tests (RDTs) as a good alternative malaria-diagnosis method in remote parts of sub-Saharan Africa. The majority of commercial RDTs currently avai...

    Authors: Pedro Berzosa, Vicenta González, Laura Taravillo, Alfredo Mayor, María Romay-Barja, Luz García, Policarpo Ncogo, Matilde Riloha and Agustín Benito

    Citation: Malaria Journal 2020 19:99

    Content type: Research

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  41. This study determined the rate of mother-to-child transmission (MTCT) of HIV among HIV positive women with placenta malaria and factors associated with placenta malaria.

    Authors: Ikechukwu I. Mbachu, Samson D. Ejikunle, Frederick Anolue, Chioma N. Mbachu, Ephraim Dike, Eke Ejikem and Chijioke Okeudo

    Citation: Malaria Journal 2020 19:97

    Content type: Research

    Published on:

  42. Anopheles fluviatilis is a species-complex comprising of four cryptic species provisionally designated as species S, T, U and V. Earlier, a 28S-rDNA based allele-specific polymerase chain reaction (ASPCR) assay w...

    Authors: Om P. Singh, Nutan Nanda, Dinesh Chandra, Deepa Jha, Tridibes Adak, Virendra K. Dua and Sarala K. Subbarao

    Citation: Malaria Journal 2020 19:96

    Content type: Methodology

    Published on:

  43. Mizoram, a northeastern state in India, shares international borders with Myanmar and Bangladesh and is considered to be one of the key routes through which drug-resistant parasites of Southeast Asia enter mai...

    Authors: Rita Zomuanpuii, Christopher L. Hmar, Khawlhring Lallawmzuala, Lal Hlimpuia, Praveen Balabaskaran Nina and Nachimuthu Senthil Kumar

    Citation: Malaria Journal 2020 19:95

    Content type: Research

    Published on:

  44. Human blood cells (erythrocytes) serve as hosts for the malaria parasite Plasmodium falciparum during its 48-h intraerythrocytic developmental cycle (IDC). Established in vitro protocols allow for the study of ho...

    Authors: Shivendra G. Tewari, Russell P. Swift, Jaques Reifman, Sean T. Prigge and Anders Wallqvist

    Citation: Malaria Journal 2020 19:94

    Content type: Research

    Published on:

  45. Despite the uptake of parasitological testing into policy and practice, appropriate prescription of anti-malarials and artemisinin-based combination therapy (ACT) in accordance with test results is variable. T...

    Authors: Ayodele Jegede, Barbara Willey, Prudence Hamade, Fredrick Oshiname, Daniel Chandramohan, IkeOluwa Ajayi, Catherine Falade, Ebenezer Baba and Jayne Webster

    Citation: Malaria Journal 2020 19:90

    Content type: Research

    Published on:

  46. Accurate Anopheles species identification is key for effective malaria vector control. Identification primarily depends on morphological analysis of field samples as well as molecular species-specific identificat...

    Authors: Yael Dahan-Moss, Allison Hendershot, Minishca Dhoogra, Henry Julius, Jacek Zawada, Maria Kaiser, Neil F. Lobo, Basil D. Brooke and Lizette L. Koekemoer

    Citation: Malaria Journal 2020 19:89

    Content type: Research

    Published on:

  47. In malaria-endemic areas, human populations are frequently exposed to immunomodulatory salivary components injected during mosquito blood feeding. The consequences on pathogen-specific immune responses are not...

    Authors: Kakou G. Aka, Dipomin F. Traoré, André B. Sagna, Dounin D. Zoh, Serge B. Assi, Bertin N’cho Tchiekoi, Akré M. Adja, Franck Remoue and Anne Poinsignon

    Citation: Malaria Journal 2020 19:83

    Content type: Research

    Published on:

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