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  1. Tanzania started implementing single screening and treatment (SST) for all pregnant women attending their first antenatal care (ANC) visits in 2014, using malaria rapid diagnostic tests (RDTs) and treating tho...

    Authors: Chonge Kitojo, Frank Chacky, Emmanuel S. Kigadye, Joseph P. Mugasa, Abdallah Lusasi, Ally Mohamed, Erik J. Reaves, Julie R. Gutman and Deus S. Ishengoma

    Citation: Malaria Journal 2021 20:256

    Content type: Research

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  2. The quality of malaria test results is crucial for optimal patient treatment and care. The Ghana Health Service is successfully shifting from presumptive clinical diagnosis and treatment of malaria to the Test...

    Authors: Mary Tetteh, Duah Dwomoh, Alexander Asamoah, Edward King Kupeh, Keziah Malm and Justice Nonvignon

    Citation: Malaria Journal 2021 20:255

    Content type: Research

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  3. Selectively targeting and treating malaria-infected individuals may further decrease parasite carriage in low-burden settings. Using a trans-disciplinary approach, a reactive treatment strategy to reduce Plasmodi...

    Authors: Joseph Okebe, Edgard Dabira, Fatou Jaiteh, Nuredin Mohammed, John Bradley, Ndey-Fatou Drammeh, Amadou Bah, Yoriko Masunaga, Jane Achan, Joan Muela Ribera, Shunmay Yeung, Julie Balen, Koen Peeters Grietens and Umberto D’Alessandro

    Citation: Malaria Journal 2021 20:253

    Content type: Research

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  4. Citation: Malaria Journal 2021 20:252

    Content type: Correction

    Published on:

    The original article was published in Malaria Journal 2021 20:197

  5. Although microscopy remains the gold standard for malaria diagnosis, little is known about its accuracy in the private health facilities in Uganda. This study evaluated the accuracy of malaria microscopy, and ...

    Authors: Tobius Mutabazi, Emmanuel Arinaitwe, Alex Ndyabakira, Emmanuel Sendaula, Alex Kakeeto, Paul Okimat, Philip Orishaba, Simon Peter Katongole, Arthur Mpimbaza, Pauline Byakika-Kibwika, Charles Karamagi, Joan Nakayaga Kalyango, Moses R. Kamya, Grant Dorsey and Joaniter I. Nankabirwa

    Citation: Malaria Journal 2021 20:250

    Content type: Research

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  6. Malaria is a fatal disease that presents clinically as a continuum of symptoms and severity, which are determined by complex host-parasite interactions. Clearance of infection is believed to be accomplished by...

    Authors: Huajing Wang, Shuo Li, Zhao Cui, Tingting Qin, Hang Shi, Ji Ma, Lanfang Li, Guihua Yu, Tingliang Jiang and Canghai Li

    Citation: Malaria Journal 2021 20:249

    Content type: Research

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  7. The Solomon Islands has made significant progress in the control of malaria through vector control, access and use of improved diagnostics and therapeutic drugs. As transmission is reduced there is a need to u...

    Authors: Tanya L. Russell, Lynn Grignard, Alan Apairamo, Nathan Kama, Albino Bobogare, Chris Drakeley and Thomas R. Burkot

    Citation: Malaria Journal 2021 20:248

    Content type: Research

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  8. Plasmodium knowlesi is now the major cause of human malaria in Malaysia, complicating malaria control efforts that must attend to the elimination of multiple Plasmodium species. Recent advances in the cultivation...

    Authors: Roberto R. Moraes Barros, Kittisak Thawnashom, Tyler J. Gibson, Jennifer S. Armistead, Ramoncito L. Caleon, Miho Kaneko, Whitney A. Kite, J. Patrick Mershon, Jacqueline K. Brockhurst, Theresa Engels, Lynn Lambert, Sachy Orr-Gonzalez, John H. Adams, Juliana M. Sá, Osamu Kaneko and Thomas E. Wellems

    Citation: Malaria Journal 2021 20:247

    Content type: Research

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  9. Plasmodium vivax is the most prevalent malaria parasite in many countries. A better understanding of human immunity to this parasite can provide new insights for vaccine development. Plasmodium vivax Reticulocyt...

    Authors: Jenni Hietanen, Anongruk Chim-ong, Jetsumon Sattabongkot and Wang Nguitragool

    Citation: Malaria Journal 2021 20:246

    Content type: Research

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  10. To overcome the limitations of conventional malaria rapid diagnostic tests (cRDTs) in diagnosing malaria in patients with low parasitaemia, ultrasensitive malaria rapid diagnostic tests (uRDTs) have recently b...

    Authors: Celestin Danwang, Fati Kirakoya-Samadoulougou and Sekou Samadoulougou

    Citation: Malaria Journal 2021 20:245

    Content type: Research

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  11. Spatio-temporal trends in mosquito-borne diseases are driven by the locations and seasonality of larval habitat. One method of disease control is to decrease the mosquito population by modifying larval habitat...

    Authors: Michelle C. Stanton, Patrick Kalonde, Kennedy Zembere, Remy Hoek Spaans and Christopher M. Jones

    Citation: Malaria Journal 2021 20:244

    Content type: Research

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  12. The current consensus on prevention of re-establishment of malaria is based on the following principles: (1) Fundamental role of general health services; (2) Surveillance; (3) Vector control; (4) Border action...

    Authors: Allan Schapira and Anatoly Kondrashin

    Citation: Malaria Journal 2021 20:243

    Content type: Opinion

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  13. Genetic diversity and parasite relatedness are essential parameters for assessing impact of interventions and understanding transmission dynamics of malaria parasites, however data on its status in Plasmodium fal...

    Authors: Agaba B. Bosco, Karen Anderson, Karryn Gresty, Christiane Prosser, David Smith, Joaniter I. Nankabirwa, Sam Nsobya, Adoke Yeka, Rhoda Namubiru, Emmanuel Arinaitwe, Paul Mbaka, John Kissa, Chae Seung Lim, Charles Karamagi, Joan K. Nakayaga, Moses R. Kamya…

    Citation: Malaria Journal 2021 20:242

    Content type: Research

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  14. To reduce the malaria burden and improve the socioeconomic status of its citizens, the Democratic Republic of Congo scaled up key malaria control interventions, especially insecticide-treated nets (ITNs), betw...

    Authors: Johanna Karemere, Ismael G. Nana, Andrew Andrada, Olivier Kakesa, Eric Mukomena Sompwe, Joris Likwela Losimba, Jacques Emina, Aboubacar Sadou, Michael Humes and Yazoumé Yé

    Citation: Malaria Journal 2021 20:241

    Content type: Research

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  15. Understanding why some infants tolerate infections, remaining asymptomatic while others succumb to repeated symptomatic malaria is beneficial for studies of naturally acquired immunity and can guide control in...

    Authors: Akua Kyerewaa Botwe, Felix Boakye Oppong, Stephaney Gyaase, Seth Owusu-Agyei, Muhammad Asghar, Kwaku Poku Asante, Anna Färnert and Faith Osier

    Citation: Malaria Journal 2021 20:240

    Content type: Research

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  16. Assessment of the genetic diversity of Plasmodium falciparum parasites from various malaria transmission settings could help to define tailored local strategies for malaria control and elimination. Such assessmen...

    Authors: Fanomezantsoa Ralinoro, Tovonahary Angelo Rakotomanga, Rianasoambolanoro Rakotosaona, Danielle A. Doll Rakoto, Didier Menard, Victor Jeannoda and Arsene Ratsimbasoa

    Citation: Malaria Journal 2021 20:239

    Content type: Research

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  17. Malaria diagnosis in many malaria-endemic countries relies mainly on the use of rapid diagnostic tests (RDTs). The majority of commercial RDTs used in Africa detect the Plasmodium falciparum histidine-rich protei...

    Authors: Mandella King, Alexander E. George, Pau Cisteró, Christine K. Tarr-Attia, Beatriz Arregui, Senga Omeonga, Haily Chen, Ana Meyer García-Sípido, Adelaida Sarukhan, Quique Bassat, Dawoh Peter Lansana and Alfredo Mayor

    Citation: Malaria Journal 2021 20:238

    Content type: Research

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  18. There are a variety of approaches being used for malaria surveillance. While active and reactive case detection have been successful in localized areas of low transmission, concerns over scalability and sustai...

    Authors: Carson Moore, Thomas Scherr, Japhet Matoba, Caison Sing’anga, Mukuma Lubinda, Phil Thuma and David Wright

    Citation: Malaria Journal 2021 20:237

    Content type: Research

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  19. Malaria remains a public health burden especially in Nigeria. To develop new malaria control and elimination strategies or refine existing ones, understanding parasite population diversity and transmission pat...

    Authors: Fehintola V. Ajogbasile, Adeyemi T. Kayode, Paul E. Oluniyi, Kazeem O. Akano, Jessica N. Uwanibe, Benjamin B. Adegboyega, Courage Philip, Oluwagboadurami G. John, Philomena J. Eromon, George Emechebe, Finimo Finimo, Nnenna Ogbulafor, Nma Jiya, Uche Okafor, Jose Ambe, Robinson D. Wammanda…

    Citation: Malaria Journal 2021 20:236

    Content type: Research

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  20. The current first-line treatments for uncomplicated malaria recommended by the National Malaria Control Programme in Mali are artemether–lumefantrine (AL) and artesunate–amodiaquine (ASAQ). From 2015 to 2016, ...

    Authors: Youssouf Diarra, Oumar Koné, Lansana Sangaré, Lassina Doumbia, Dade Bouye Ben Haidara, Mouctar Diallo, Ababacar Maiga, Hamadoun A. Sango, Halidou Sidibé, Jules Mihigo, Douglas Nace, Dragan Ljolje, Eldin Talundzic, Venkatachalam Udhayakumar, Erin Eckert, Celia J. Woodfill…

    Citation: Malaria Journal 2021 20:235

    Content type: Research

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  21. The emergence of insecticide resistance is a major threat to malaria control programmes in Africa, with many different factors contributing to insecticide resistance in its vectors, Anopheles mosquitoes. CYP6M2 h...

    Authors: Martin G. Wagah, Petra Korlević, Christopher Clarkson, Alistair Miles, Mara K. N. Lawniczak and Alex Makunin

    Citation: Malaria Journal 2021 20:234

    Content type: Research

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  22. The coronavirus disease 2019 (COVID-19) pandemic has posed a unique challenge to health care systems globally. To curb COVID-19 transmission, mitigation measures such as travel restrictions, border closures, c...

    Authors: Samuel Gavi, Oscar Tapera, Joseph Mberikunashe and Mufaro Kanyangarara

    Citation: Malaria Journal 2021 20:233

    Content type: Case study

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  23. Current standard interventions are not universally sufficient for malaria elimination. The effects of community-based house improvement (HI) and larval source management (LSM) as supplementary interventions to...

    Authors: Robert S. McCann, Alinune N. Kabaghe, Paula Moraga, Steven Gowelo, Monicah M. Mburu, Tinashe Tizifa, Michael G. Chipeta, William Nkhono, Aurelio Di Pasquale, Nicolas Maire, Lucinda Manda-Taylor, Themba Mzilahowa, Henk van den Berg, Peter J. Diggle, Dianne J. Terlouw, Willem Takken…

    Citation: Malaria Journal 2021 20:232

    Content type: Research

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  24. In malaria endemic regions, intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) is recommended for all pregnant women during prenatal consultation, from the fourth month of pregnancy up ...

    Authors: Oumar Sangho, Moctar Tounkara, Lillian Joyce Whiting-Collins, Madeleine Beebe, Peter J. Winch and Seydou Doumbia

    Citation: Malaria Journal 2021 20:231

    Content type: Research

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  25. Mosquito species from the Anopheles gambiae complex and the Anopheles funestus group are dominant African malaria vectors. Mosquito microbiota play vital roles in physiology and vector competence. Recent research...

    Authors: Bianca E Silva, Zvifadzo Matsena Zingoni, Lizette L. Koekemoer and Yael L. Dahan-Moss

    Citation: Malaria Journal 2021 20:230

    Content type: Research

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  26. Malaria is a major public health problem in India and accounts for about 88% of malaria burden in South-East Asia. India alone accounted for 2% of total malaria cases globally. Anti-malarial drug resistance is...

    Authors: Sri Krishna, Sweta Mishra, Prakash Tiwari, Anup K. Vishwakarma, Sushrikanta Khandai, Suyesh Shrivastava, Anil K. Verma, Shashikant Tiwari, Hari Barman, Surendra Jhariya, Pradeep Tiwari, Anup S. Tidgam, Brij M. Varun, Sunil Singh, Naresh Yerane, Chintaman R. Tembhurne…

    Citation: Malaria Journal 2021 20:229

    Content type: Research

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  27. The over-distributed pattern of malaria transmission has led to attempts to define malaria “hotspots” that could be targeted for purposes of malaria control in Africa. However, few studies have investigated th...

    Authors: Alice Kamau, Grace Mtanje, Christine Mataza, Philip Bejon and Robert W. Snow

    Citation: Malaria Journal 2021 20:227

    Content type: Research

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  28. Malaria vector control relies upon the use of insecticide-treated nets and indoor residual spraying. However, as the emergency of insecticide resistance in malaria vectors grows, the effectiveness of these mea...

    Authors: Alphonse Traoré, Gérard Niyondiko, Antoine Sanou, Franck Langevin, N’Falé Sagnon, Adama Gansané and Moussa Wamdaogo Guelbeogo

    Citation: Malaria Journal 2021 20:226

    Content type: Research

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  29. Loop-mediated isothermal amplification (LAMP) for malaria diagnosis at the point of care (POC) depends on the detection capacity of synthesized nucleic acids and the specificity of the amplification target. To...

    Authors: Oscar Nolasco, Jhoel Montoya, Ana L. Rosales Rosas, Scarlett Barrientos, Anna Rosanas-Urgell and Dionicia Gamboa

    Citation: Malaria Journal 2021 20:225

    Content type: Research

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  30. Sixty percent of the Ethiopia population is at risk of malaria, with the highest prevalence reported in Gambella (6%) and Benishangul-Gumuz (3%) regions. Within these regions are large agricultural development...

    Authors: Yehualashet Tadesse, Seth R. Irish, Sheleme Chibsa, Sisay Dugassa, Lena M. Lorenz, Asfawesen Gebreyohannes, Hiwot Teka, Hiwot Solomon, Eshetu Gezahegn, Yonas Petros, Mesfin Haile, Mesfin Eshetu and Matthew Murphy

    Citation: Malaria Journal 2021 20:224

    Content type: Research

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  31. To improve the coverage of intermittent preventive treatment of malaria in pregnancy (IPTp) in Africa, Medicines for Malaria Venture (MMV) developed, tested and validated a new packaging of sulfadoxine–pyrimet...

    Authors: Sylvain Landry Birane Faye and Maud Majeres Lugand

    Citation: Malaria Journal 2021 20:223

    Content type: Research

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  32. For uncomplicated Plasmodium falciparum malaria, highly efficacious single-dose treatments are expected to increase compliance and improve treatment outcomes, and thereby may slow the development of resistance. T...

    Authors: Yeka Adoke, Rella Zoleko-Manego, Serge Ouoba, Alfred B. Tiono, Grace Kaguthi, Juvêncio Eduardo Bonzela, Tran Thanh Duong, Alain Nahum, Marielle Bouyou-Akotet, Bernhards Ogutu, Alphonse Ouedraogo, Fiona Macintyre, Andreas Jessel, Bart Laurijssens, Mohammed H. Cherkaoui-Rbati, Cathy Cantalloube…

    Citation: Malaria Journal 2021 20:222

    Content type: Research

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  33. Efforts to study the biology of Plasmodium vivax liver stages, particularly the latent hypnozoites, have been hampered by the limited availability of P. vivax sporozoites. Anopheles stephensi is a major urban mal...

    Authors: Ajeet Kumar Mohanty, Charles de Souza, Deepika Harjai, Prathamesh Ghavanalkar, Mezia Fernandes, Anvily Almeida, Jayashri Walke, Suresh Kumar Manoharan, Ligia Pereira, Rashmi Dash, Anjali Mascarenhas, Edwin Gomes, Thanyapit Thita, Laura Chery, Anupkumar R. Anvikar, Ashwani Kumar…

    Citation: Malaria Journal 2021 20:221

    Content type: Research

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  34. Sleeping under an ITN reduces contact with mosquitoes through the combination of a physical barrier and an insecticidal effect, which reduces the incidence of malaria. The 2016–2020 Burkina Faso National Malar...

    Authors: Mahamadi Tassembedo, Soumaila Coulibaly and Boukary Ouedraogo

    Citation: Malaria Journal 2021 20:220

    Content type: Research

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  35. Insecticide-treated bed nets (ITNs) are widely used for the prevention and control of malaria. In Guatemala, since 2006, ITNs have been distributed free of charge in the highest risk malaria-endemic areas and ...

    Authors: María Eugenia Castellanos, Soledad Rodas, José Guillermo Juárez, Juan Carlos Lol, Sayra Chanquin, Zoraida Morales, Lucrecia Vizcaino, Stephen C. Smith, Jodi Vanden Eng, Henok G. Woldu, Audrey Lenhart and Norma Padilla

    Citation: Malaria Journal 2021 20:219

    Content type: Research

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  36. Malaria control and elimination strategies are based on levels of transmission that are usually determined by data collected from health facilities. In endemic areas, asymptomatic Plasmodium infection is thought ...

    Authors: Aida Sadikh Badiane, Tolla Ndiaye, Alphonse Birane Thiaw, Deme Awa Binta, Mamadou Alpha Diallo, Mame Cheikh Seck, Khadim Diongue, Mamane Nassirou Garba, Mouhamadou Ndiaye and Daouda Ndiaye

    Citation: Malaria Journal 2021 20:218

    Content type: Research

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  37. The radical cure of Plasmodium vivax requires treatment with an 8-aminoquinoline drug, such as primaquine and tafenoquine, to eradicate liver hypnozoite stages, which can reactivate to cause relapsing infections....

    Authors: Nora Engel, Cristian Ghergu, Mohammad Abdul Matin, Mohammad Golam Kibria, Kamala Thriemer, Ric N. Price, Xavier C. Ding, Rosalind E. Howes, Benedikt Ley, Sandra Incardona and Mohammad Shafiul Alam

    Citation: Malaria Journal 2021 20:217

    Content type: Research

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  38. In French Guiana, gold miners working illegally represents a major reservoir of malaria. This mobile population, mainly of Brazilian descent, enters the French Guianese forest from neighbouring countries, Suri...

    Authors: Muriel Suzanne Galindo, Yann Lambert, Louise Mutricy, Laure Garancher, Jane Bordalo Miller, José Hermenegildo Gomes, Alice Sanna, Cassio Peterka, Hélène Hilderal, Hedley Cairo, Helene Hiwat, Mathieu Nacher, Martha Cecilia Suárez-Mutis, Stephen Vreden and Maylis Douine

    Citation: Malaria Journal 2021 20:216

    Content type: Methodology

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  39. European travellers to endemic countries are at risk of malaria and may be affected by a different range of co-morbidities than natives of endemic regions. The safety profile, especially cardiac issues, of art...

    Authors: Nicolas Vignier, Olivier Bouchaud, Andrea Angheben, Emmanuel Bottieau, Guido Calleri, Joaquín Salas-Coronas, Charlotte Martin, José Manuel Ramos, Matthieu Mechain, Christophe Rapp, Hans-Dieter Nothdurft, Maria Velasco, Azucena Bardají, Gerardo Rojo-Marcos, Leo G. Visser, Christoph Hatz…

    Citation: Malaria Journal 2021 20:214

    Content type: Research

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  40. Regular monitoring of anti-malarial drug efficacy is vital for establishing rational malaria treatment guidelines and ensuring adequate treatment outcomes. This study aimed to synthesize the available evidence...

    Authors: Abdulhakim Abamecha, Daniel Yilma, Wondimagegn Adissu, Delenasaw Yewhalaw and Alemseged Abdissa

    Citation: Malaria Journal 2021 20:213

    Content type: Research

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  41. Understanding of the impacts of climatic variability on human health remains poor despite a possibly increasing burden of vector-borne diseases under global warming. Numerous socioeconomic variables make such ...

    Authors: Tzu Tung Chen, Fredrik Charpentier Ljungqvist, Helene Castenbrandt, Franziska Hildebrandt, Mathias Mølbak Ingholt, Jenny C. Hesson, Johan Ankarklev, Kristina Seftigen and Hans W. Linderholm

    Citation: Malaria Journal 2021 20:212

    Content type: Case study

    Published on:

  42. Malaria in endemic countries is often asymptomatic during pregnancy, but it has substantial consequences for both the mother and her unborn baby. During pregnancy, anaemia is an important consequence of malari...

    Authors: Toussaint Rouamba, Sékou Samadoulougou, Mady Ouédraogo, Hervé Hien, Halidou Tinto and Fati Kirakoya-Samadoulougou

    Citation: Malaria Journal 2021 20:211

    Content type: Research

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  43. Imported malaria parasites with anti-malarial drug resistance (ADR) from Africa is a serious public health challenge in non-malarial regions, including Wuhan, China. It is crucial to assess the ADR status in A...

    Authors: Weijia Cheng, Xiaonan Song, Huabing Tan, Kai Wu and Jian Li

    Citation: Malaria Journal 2021 20:209

    Content type: Research

    Published on:

  44. In malaria elimination settings, available metrics for malaria surveillance have been insufficient to measure the performance of passive case detection adequately. An indicator for malaria suspected cases with...

    Authors: Diego Rios-Zertuche, Keith H. Carter, Katie Panhorst Harris, Max Thom, Maria Paola Zúñiga-Brenes, Pedro Bernal-Lara, Álvaro González-Marmol, Casey K. Johanns, Bernardo Hernández, Erin Palmisano, Rebecca Cogen, Paulami Naik, Charbel El Bcheraoui, David L. Smith, Ali H. Mokdad and Emma Iriarte

    Citation: Malaria Journal 2021 20:208

    Content type: Research

    Published on:

  45. The Plasmodium falciparum antigen histidine rich protein 2 (HRP2) is a preferred target for malaria rapid diagnostic tests (RDTs) because of its abundant production by the parasite and thermal stability. As a res...

    Authors: Amy Kong, Scott A. Wilson, Yong Ah, Douglas Nace, Eric Rogier and Michael Aidoo

    Citation: Malaria Journal 2021 20:207

    Content type: Research

    Published on:

  46. Drug-resistant falciparum malaria is an increasing public health burden. This study examined the magnitude of Plasmodium falciparum infection and the patterns and predictors of treatment failure in Vietnam.

    Authors: Minh Cuong Duong, Oanh Kieu Nguyet Pham, Phong Thanh Nguyen, Van Vinh Chau Nguyen and Phu Hoan Nguyen

    Citation: Malaria Journal 2021 20:205

    Content type: Research

    Published on:

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