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  1. Application methods of |Attractive Toxic Sugar Baits (ATSB) need to be improved for wide-scale use, and effects on non-target organisms (NTOs) must be assessed. The goals of this study were to determine, at th...

    Authors: Rabiatou A. Diarra, Mohamed M. Traore, Amy Junnila, Sekou F. Traore, Seydou Doumbia, Edita E. Revay, Vasiliy D. Kravchenko, Yosef Schlein, Kristopher L. Arheart, Petrányi Gergely, Axel Hausmann, Robert Beck, Rui-De Xue, Alex M. Prozorov, Aboubakr S. Kone, Silas Majambere…

    Citation: Malaria Journal 2021 20:184

    Content type: Research

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  2. Malaria transmission-blocking vaccines (TBVs) could help break the cycle of malaria transmission by conferring community rather than individual protection. When introducing new intervention strategies, uptake is ...

    Authors: Kaci D. McCoy, Caroline T. Weldon, Rashid Ansumana, Joseph M. Lamin, David A. Stenger, Sadie J. Ryan, Kevin Bardosh, Kathryn H. Jacobsen and Rhoel R. Dinglasan

    Citation: Malaria Journal 2021 20:183

    Content type: Research

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  3. The malaria control programme in Indonesia has successfully brought down malaria incidence in many parts in Indonesia, including Aceh Province. Clinical manifestation of reported malaria cases in Aceh varied w...

    Authors: Kurnia Fitri Jamil, Nandha Rizki Pratama, Sylvia Sance Marantina, Harapan Harapan, Muhammad Riza Kurniawan, Tjut Mariam Zanaria, Jontari Hutagalung, Ismail Ekoprayitno Rozi, Puji Budi Setia Asih, Supargiyono and Din Syafruddin

    Citation: Malaria Journal 2021 20:182

    Content type: Research

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  4. Volunteer infection studies have become a standard model for evaluating drug efficacy against Plasmodium infections. Molecular techniques such as qPCR are used in these studies due to their ability to provide rob...

    Authors: Claire Y. T. Wang, Emma L. Ballard, Zuleima Pava, Louise Marquart, Jane Gaydon, Sean C. Murphy, David Whiley, Peter O’Rourke and James S. McCarthy

    Citation: Malaria Journal 2021 20:181

    Content type: Research

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  5. The effectiveness of long-lasting insecticidal nets (LLIN), the primary method for preventing malaria in Africa, is compromised by evolution and spread of pyrethroid resistance. Further gains require new insec...

    Authors: Patrick K. Tungu, Elisante Michael, Wema Sudi, William W. Kisinza and Mark Rowland

    Citation: Malaria Journal 2021 20:180

    Content type: Research

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  6. Plasmodium knowlesi is recognized as the fifth Plasmodium species causing malaria in humans. It is morphologically similar to the human malaria parasite Plasmodium malariae, so molecular detection should be used ...

    Authors: Aongart Mahittikorn, Frederick Ramirez Masangkay, Kwuntida Uthaisar Kotepui, Giovanni De Jesus Milanez and Manas Kotepui

    Citation: Malaria Journal 2021 20:179

    Content type: Research

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  7. A goal of malaria epidemiological interventions is the detection and treatment of parasite reservoirs in endemic areas—an activity that is expected to reduce local transmission. Since the gametocyte is the onl...

    Authors: Ayleen Kosasih, Cristian Koepfli, M. Sopiyudin Dahlan, William A. Hawley, J. Kevin Baird, Ivo Mueller, Neil F. Lobo and Inge Sutanto

    Citation: Malaria Journal 2021 20:177

    Content type: Research

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  8. K13 propeller (k13) polymorphism are useful molecular markers for tracking the emergence and spread of artemisinin resistance in Plasmodium falciparum. Polymorphisms are reported from Cambodia with rapid invasion...

    Authors: Najia Karim Ghanchi, Bushra Qurashi, Hadiqa Raees and Mohammad Asim Beg

    Citation: Malaria Journal 2021 20:176

    Content type: Research

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  9. The emergence of artemisinin resistance in Southeast Asia and Plasmodium falciparum kelch13 propeller gene mutations in sub-Saharan African pose the greatest threat to global efforts to control malaria. This is a...

    Authors: Dawit Getachew Assefa, Eden Dagnachew Zeleke, Delayehu Bekele, Hanna Amanuel Tesfahunei, Emnet Getachew, Michele Joseph and Tsegahun Manyazewal

    Citation: Malaria Journal 2021 20:174

    Content type: Research

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  10. Widespread insecticide resistance to pyrethroids could thwart progress towards elimination. Recently, the World Health Organization has encouraged the use of non-pyrethroid insecticides to reduce the spread of...

    Authors: Joseph Keating, Joshua O. Yukich, John M. Miller, Sara Scates, Busiku Hamainza, Thomas P. Eisele and Adam Bennett

    Citation: Malaria Journal 2021 20:173

    Content type: Research

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  11. Cape Verde is an archipelago located off the West African coast and is in a pre-elimination phase of malaria control. Since 2010, fewer than 20 Plasmodium falciparum malaria cases have been reported annually, exc...

    Authors: Silvania Da Veiga Leal, Daniel Ward, Susana Campino, Ernest Diez Benavente, Amy Ibrahim, Tânia Claret, Varela Isaías, Davidson Monteiro, Taane G. Clark, Luzia Gonçalves, Tomas Valdez, Maria da Luz Lima Mendonça, Henrique Silveira and Fatima Nogueira

    Citation: Malaria Journal 2021 20:172

    Content type: Research

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  12. As insecticide-treated nets (ITNs) wear out and are disposed, some household members are prioritized to use remaining ITNs. This study assessed how nets are allocated within households to individuals of differ...

    Authors: Zawadi M. Mboma, Charles Festo, Lena M. Lorenz, Dennis J. Massue, William N. Kisinza, John Bradley, Jason D. Moore, Renata Mandike, Ikupa Akim, Jo Lines, Hans J. Overgaard and Sarah J. Moore

    Citation: Malaria Journal 2021 20:171

    Content type: Research

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  13. Population suppression gene drive has been proposed as a strategy for malaria vector control. A CRISPR-Cas9-based transgene homing at the doublesex locus (dsxFCRISPRh) has recently been shown to increase rapidly ...

    Authors: John B. Connolly, John D. Mumford, Silke Fuchs, Geoff Turner, Camilla Beech, Ace R. North and Austin Burt

    Citation: Malaria Journal 2021 20:170

    Content type: Research

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  14. Treatment of clinical Plasmodium falciparum malaria with sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) is associated with increased post-treatment gametocyte carriage. The effect of seasonal malaria chemopr...

    Authors: Abdullahi Ahmad, Aurelia Prom, John Bradley, Mamadou Ndiath, Blessed Etoketim, Mamadou Bah, Jean-Pierre Van Geertruyden, Chris Drakeley, Teun Bousema, Jane Achan and Umberto D’Alessandro

    Citation: Malaria Journal 2021 20:169

    Content type: Research

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  15. Although it is accepted that long-lasting insecticidal net (LLIN) use is an effective means to prevent malaria, children aged 5 to 15 years do not appear to be sufficiently protected in Madagascar; the malaria...

    Authors: Ammy Fiadanana Njatosoa, Chiarella Mattern, Dolorès Pourette, Thomas Kesteman, Elliot Rakotomanana, Bakoly Rahaivondrafahitra, Mauricette Andriamananjara, Aina Harimanana, Jocelyn Razafindrakoto, Emma Raboanary, Andry Andrianasolo and Christophe Rogier

    Citation: Malaria Journal 2021 20:168

    Content type: Research

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  16. To achieve malaria elimination in the Greater Mekong Subregion, including Myanmar, it is necessary to ensure all malaria cases are detected, treated, and reported in a timely manner. Mobile phone-based applica...

    Authors: Win Han Oo, Win Htike, Julia C. Cutts, Kyawt Mon Win, Kaung Myat Thu, May Chan Oo, Galau Naw Hkawng, Paul A. Agius, Pyae Phyo Htoon, Nick Scott, Ellen Kearney, Clarissa Moreira, Alisa Pedrana, Mark Stoove, Aung Thi, Ye Win Aung…

    Citation: Malaria Journal 2021 20:167

    Content type: Research

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  17. As an alternative to PCR methods, LAMP is increasingly being used in the field of molecular diagnostics. Under isothermal conditions at 65 °C, the entire procedure takes approximately 30 min to complete. In th...

    Authors: Meng Yee Lai, Choo Huck Ooi and Yee Ling Lau

    Citation: Malaria Journal 2021 20:166

    Content type: Research

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  18. Malaria is a principal cause of illness and death in countries where the disease is endemic. Personal protection against mosquitoes using repellents could be a useful method that can reduce and/or prevent tran...

    Authors: António B. Mapossa, Walter W. Focke, Robert K. Tewo, René Androsch and Taneshka Kruger

    Citation: Malaria Journal 2021 20:165

    Content type: Review

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  19. Wide-spread implementation of treatment regimens for the radical cure of vivax malaria is hindered by a range of factors. This has resulted in an increase in the relative proportion of vivax malaria and is an ...

    Authors: Bipin Adhikari, Ghulam Rhahim Awab and Lorenz von Seidlein

    Citation: Malaria Journal 2021 20:164

    Content type: Research

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  20. Approximately 70% of Kenya’s population is at risk for malaria. The core vector control methods in Kenya are insecticide-treated mosquito nets (ITNs) and indoor residual spraying, with supplementary larval sou...

    Authors: Prisca A. Oria, Vincent Moshi, Julius I. Odero, Sheila Ekodir, April Monroe, Steven A. Harvey, Eric Ochomo and Danielle Piccinini Black

    Citation: Malaria Journal 2021 20:163

    Content type: Research

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  21. In Namibia, as in many malaria elimination settings, reactive case detection (RACD), or malaria testing and treatment around index cases, is a standard intervention. Reactive focal mass drug administration (rf...

    Authors: Kathryn W. Roberts, Cara Smith Gueye, Kimberly Baltzell, Henry Ntuku, Patrick McCreesh, Alysse Maglior, Brooke Whittemore, Petrina Uusiku, Davis Mumbengegwi, Immo Kleinschmidt, Roly Gosling and Michelle S. Hsiang

    Citation: Malaria Journal 2021 20:162

    Content type: Research

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  22. Accumulating evidence suggest that compromised CYP2D6 enzyme activity caused by gene mutation could contribute to primaquine failure for the radical cure of vivax malaria. The current study aims to preliminari...

    Authors: Herong Huang, Ying Dong, Yanchun Xu, Yan Deng, Canglin Zhang, Shuping Liu, Mengni Chen and Yan Liu

    Citation: Malaria Journal 2021 20:160

    Content type: Research

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  23. Eswatini was the first country in sub-Saharan Africa to pass a National Malaria Elimination Policy in 2011, and later set a target for elimination by the year 2020. This case study aimed to review the malaria ...

    Authors: Theresia Estomih Nkya, Ulrike Fillinger, Makhoselive Dlamini, Onyango P. Sangoro, Rose Marubu, Zulisile Zulu, Emmanuel Chanda, Clifford Maina Mutero and Quinton Dlamini

    Citation: Malaria Journal 2021 20:159

    Content type: Case study

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  24. China has accumulated considerable experience in malaria control and elimination over the past decades. Many research papers have been published in Chinese journals. This study intends to describe the developm...

    Authors: Yan-Qiu Du, Guo-Ding Zhu, Jun Cao and Jia-Yan Huang

    Citation: Malaria Journal 2021 20:158

    Content type: Research

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  25. Numerous studies have been undertaken to advance knowledge of apicomplexan parasites infecting vertebrates, including humans. Of these parasites, the genus Plasmodium has been most extensively studied because of ...

    Authors: Mercia Rasoanoro, Steven M. Goodman, Milijaona Randrianarivelojosia, Mbola Rakotondratsimba, Koussay Dellagi, Pablo Tortosa and Beza Ramasindrazana

    Citation: Malaria Journal 2021 20:157

    Content type: Research

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  26. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Thomas A. Anyorigiya, Sandra Castel, Katya Mauf, Frank Atuguba, Bernhards Ogutu, Abraham Oduro, David Dosoo, Kwaku-Poku Asante, Seth Owusu-Agyei, Alexander Dodoo, Abraham Hodgson, Fred Binka, Lesley J. Workman, Elizabeth N. Allen, Paolo Denti, Lubbe Wiesner…

    Citation: Malaria Journal 2021 20:156

    Content type: Correction

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    The original article was published in Malaria Journal 2021 20:18

  27. Integrated vector management (IVM) is defined as a rational decision-making process for the optimal use of resources for vector control. The IVM approach is based on the premise that effective control of vecto...

    Authors: Peter N. Ng’ang’a, Polycarp Aduogo and Clifford M. Mutero

    Citation: Malaria Journal 2021 20:155

    Content type: Case study

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  28. Understanding malaria vector’s population dynamics and their spatial distribution is important to define when and where the largest infection risks occur and implement appropriate control strategies. In this s...

    Authors: Kasahun Eba, Tibebu Habtewold, Delenasaw Yewhalaw, George K. Christophides and Luc Duchateau

    Citation: Malaria Journal 2021 20:154

    Content type: Research

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  29. Malaria is one of the most important public health problems in Ethiopia contributing to significant patient morbidity and mortality. Prompt diagnosis and effective malaria case management through public, priva...

    Authors: Mesele Damte Argaw, Thandisizwe Redford Mavundla and Kassa Daka Gidebo

    Citation: Malaria Journal 2021 20:153

    Content type: Research

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  30. Anti-malarial drug resistance remains a key concern for the global fight against malaria. In Ghana sulfadoxine-pyrimethamine (SP) is used for intermittent preventive treatment of malaria in pregnancy and combi...

    Authors: Lucas N. Amenga-Etego, Victor Asoala, Godfred Agongo, Christopher Jacob, Sonia Goncalves, Gordon A. Awandare, Kirk A. Rockett and Dominic Kwiatkowski

    Citation: Malaria Journal 2021 20:152

    Content type: Research

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  31. Attractive targeted sugar baits (ATSBs) are a promising new tool for malaria control as they can target outdoor-feeding mosquito populations, in contrast to current vector control tools which predominantly tar...

    Authors: Keith J. Fraser, Lazaro Mwandigha, Sekou F. Traore, Mohamed M. Traore, Seydou Doumbia, Amy Junnila, Edita Revay, John C. Beier, John M. Marshall, Azra C. Ghani and Gunter Müller

    Citation: Malaria Journal 2021 20:151

    Content type: Research

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  32. Mosquito larval source management (LSM) is a key outdoor malaria vector control strategy in rural communities in sub-Saharan Africa. Knowledge of this strategy is important for optimal design and implementatio...

    Authors: Mphatso Kamndaya, Dumisani Mfipa and Kingsley Lungu

    Citation: Malaria Journal 2021 20:150

    Content type: Research

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  33. The African Union’s High-Level Panel on Emerging Technologies identified gene drive mosquitoes as a priority technology for malaria elimination. The first field trials are expected in 5–10 years in Uganda, Mal...

    Authors: Sarah Hartley, Robert D. J. Smith, Adam Kokotovich, Chris Opesen, Tibebu Habtewold, Katie Ledingham, Ben Raymond and Charles B. Rwabukwali

    Citation: Malaria Journal 2021 20:149

    Content type: Research

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  34. The malaria vector Anopheles funestus is increasingly recognized as a dominant vector of residual transmission in many African settings. Efforts to better understand its biology and control are significantly impe...

    Authors: Halfan S. Ngowo, Emmanuel E. Hape, Jason Matthiopoulos, Heather M. Ferguson and Fredros O. Okumu

    Citation: Malaria Journal 2021 20:148

    Content type: Research

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  35. Yunnan Province was considered the most difficult place in China for malaria elimination because of its complex malaria epidemiology, heterogeneous ecological features, relatively modest economic development, ...

    Authors: Xiao-Hong Li, Hong-Ning Zhou, Jian-Wei Xu, Zu-Rui Lin, Xiao-Dong Sun, Jia-Yin Li, Xian-Xian Lin, Yan Xie, Pedro Alonso and Heng-Lin Yang

    Citation: Malaria Journal 2021 20:147

    Content type: Review

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  36. Vivax malaria diagnosis remains a challenge in malaria elimination, with current point of care rapid diagnostic tests (RDT) missing many clinically significant infections because of usually lower peripheral pa...

    Authors: Gisely Cardoso de Melo, Rebeca Linhares Abreu Netto, Victor Irungu Mwangi, Yanka Evellyn Alves Rodrigues Salazar, Vanderson de Souza Sampaio, Wuelton Marcelo Monteiro, Fernando Fonseca de Almeida e Val, Anne Rocheleau, Priyaleela Thota and Marcus Vinícius Guimarães Lacerda

    Citation: Malaria Journal 2021 20:146

    Content type: Research

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  37. Plasmodium falciparum strains with mutations/deletions of the genes encoding the histidine-rich proteins 2/3 (pfhrp2/3) have emerged during the last 10 years leading to false-negative results in HRP2-based rapid ...

    Authors: Stefan Schlabe, Ingrid Reiter-Owona, Tamara Nordmann, Ramona Dolscheid-Pommerich, Egbert Tannich, Achim Hoerauf and Jürgen Rockstroh

    Citation: Malaria Journal 2021 20:145

    Content type: Case report

    Published on:

  38. The national policy for malaria treatment of the Democratic Republic of Congo recommends two first-line artemisinin-based combinations for the treatment of uncomplicated malaria: artesunate-amodiaquine and art...

    Authors: Doudou M. Yobi, Nadine K. Kayiba, Dieudonné M. Mvumbi, Raphael Boreux, Pius Z. Kabututu, Hippolyte N. T. Situakibanza, Solange E. Umesumbu, Patrick De Mol, Niko Speybroeck, Georges L. Mvumbi and Marie-Pierre Hayette

    Citation: Malaria Journal 2021 20:144

    Content type: Research

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  39. As malaria cases increase in some of the highest burden countries, more strategic deployment of new and proven interventions must be evaluated to meet global malaria reduction goals.

    Authors: Sergi Alonso, Carlos J. Chaccour, Joseph Wagman, Baltazar Candrinho, Rodaly Muthoni, Abuchahama Saifodine, Francisco Saute, Molly Robertson and Rose Zulliger

    Citation: Malaria Journal 2021 20:143

    Content type: Research

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  40. Malaria is the single largest cause of illness in Uganda. Since the year 2008, the Global Fund has rolled out several funding streams for malaria control in Uganda. Among these are mechanisms aimed at increasi...

    Authors: Denis Kibira, Anthony Ssebagereka, Hendrika A. van den Ham, Jimmy Opigo, Henry Katamba, Morries Seru, Tim Reed, Hubert G. Leufkens and Aukje K. Mantel-Teeuwisse

    Citation: Malaria Journal 2021 20:142

    Content type: Research

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  41. The malaria mosquito Anopheles punctipennis, a widely distributed species in North America, is capable of transmitting human malaria and is actively involved in the transmission of the ungulate malaria parasite P...

    Authors: James M. Hodge, Andrey A. Yurchenko, Dmitriy A. Karagodin, Reem A. Masri, Ryan C. Smith, Mikhail I. Gordeev and Maria V. Sharakhova

    Citation: Malaria Journal 2021 20:141

    Content type: Research

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  42. To strengthen the fight against malaria, it is imperative to identify weaknesses and possible solutions in order to improve programmes implementation. This study reports experiences gained from collaboration b...

    Authors: Tete S. Amouh, Saidou Malam Ekoye, Césaire D. Ahanhanzo, Tinga Robert Guiguemdé and Issiaka Sombié

    Citation: Malaria Journal 2021 20:140

    Content type: Research

    Published on:

  43. Malaria control system (MCS), an Information technology (IT)-driven surveillance and monitoring intervention is being adopted for elimination of malaria in Mangaluru city, Karnataka, India since October 2015. ...

    Authors: B. Shantharam Baliga, Shrikala Baliga, Animesh Jain, Naveen Kulal, Manu Kumar, Naren Koduvattat, B. G. Prakash Kumar, Arun Kumar and Susanta K. Ghosh

    Citation: Malaria Journal 2021 20:139

    Content type: Methodology

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  44. Long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are the malaria control interventions primarily responsible for reductions in transmission intensity across sub-Saharan Africa. These i...

    Authors: Henry Ddumba Mawejje, Maxwell Kilama, Simon P. Kigozi, Alex K. Musiime, Moses Kamya, Jo Lines, Steven W. Lindsay, David Smith, Grant Dorsey, Martin J. Donnelly and Sarah G. Staedke

    Citation: Malaria Journal 2021 20:138

    Content type: Research

    Published on:

  45. Cross-border malaria is a major barrier to elimination efforts. Along the Venezuela-Brazil-Guyana border, intense human mobility fueled primarily by a humanitarian crisis and illegal gold mining activities has...

    Authors: Nicholas J. Arisco, Cassio Peterka and Marcia C. Castro

    Citation: Malaria Journal 2021 20:135

    Content type: Research

    Published on:

  46. Different forms of mosquito modifications are being considered as potential high-impact and low-cost tools for future malaria control in Africa. Although still under evaluation, the eventual success of these t...

    Authors: Marceline F. Finda, Fredros O. Okumu, Elihaika Minja, Rukiyah Njalambaha, Winfrida Mponzi, Brian B. Tarimo, Prosper Chaki, Javier Lezaun, Ann H. Kelly and Nicola Christofides

    Citation: Malaria Journal 2021 20:134

    Content type: Research

    Published on:

    The Correction to this article has been published in Malaria Journal 2021 20:257

  47. Rapid and sensitive diagnostics are critical tools for clinical case management and public health control efforts. Both capillary and venous blood are currently used for malaria detection and while diagnostic ...

    Authors: Tomasz A. Leski, Chris Rowe Taitt, Umaru Bangura, Joseph Lahai, Joseph M. Lamin, Victoria Baio, Mohamed S. Koroma, Abdulai G. Swaray, Kathryn H. Jacobsen, Olivia Jackson, Brian W. Jones, Cynthia L. Phillips, Rashid Ansumana and David A. Stenger

    Citation: Malaria Journal 2021 20:133

    Content type: Research

    Published on:

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