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  1. Malaria kills over 400,000 people each year and nearly half the world’s population live in at-risk areas. Progress against malaria has recently stalled, highlighting the need for developing novel therapeutics....

    Authors: Jonathan M. Machin, Anastassia L. Kantsadi and Ioannis Vakonakis

    Citation: Malaria Journal 2019 18:388

    Content type: Research

    Published on:

  2. Malaria rapid diagnostic tests (RDTs) emerged in the early 1990s into largely unregulated markets, and uncertain field performance was a major concern for the acceptance of tests for malaria case management. T...

    Authors: Jane Cunningham, Sophie Jones, Michelle L. Gatton, John W. Barnwell, Qin Cheng, Peter L. Chiodini, Jeffrey Glenn, Sandra Incardona, Cara Kosack, Jennifer Luchavez, Didier Menard, Sina Nhem, Wellington Oyibo, Roxanne R. Rees-Channer, Iveth Gonzalez and David Bell

    Citation: Malaria Journal 2019 18:387

    Content type: Review

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  3. Measuring human exposure to mosquito bites is a crucial component of vector-borne disease surveillance. For malaria vectors, the human landing catch (HLC) remains the gold standard for direct estimation of exp...

    Authors: Antoine Sanou, W. Moussa Guelbéogo, Luca Nelli, K. Hyacinth Toé, Soumanaba Zongo, Pierre Ouédraogo, Fatoumata Cissé, Nosrat Mirzai, Jason Matthiopoulos, N’falé Sagnon and Heather M. Ferguson

    Citation: Malaria Journal 2019 18:386

    Content type: Research

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  4. Long-lasting insecticidal nets (LLINs) treated with pyrethroids are the foundation of malaria control in sub-Saharan Africa. Rising pyrethroid resistance in vectors, however, has driven the development of alte...

    Authors: Kobié H. Toé, Frank Mechan, Julie-Anne A. Tangena, Marion Morris, Joanna Solino, Emile F. S. Tchicaya, Alphonse Traoré, Hanafy Ismail, James Maas, Natalie Lissenden, Margaret Pinder, Steve W. Lindsay, Alfred B. Tiono, Hilary Ranson and N’Falé Sagnon

    Citation: Malaria Journal 2019 18:383

    Content type: Research

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  5. Rhoptries are the large, paired, secretory organelles located at the apical tip of the malaria merozoite that are considered important for parasite invasion processes. Plasmodium vivax rhoptry proteins have been ...

    Authors: Piyawan Kochayoo, Siriruk Changrob, Kittikorn Wangriatisak, Seong Kyun Lee, Patchanee Chootong and Eun-Taek Han

    Citation: Malaria Journal 2019 18:382

    Content type: Research

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  6. Malaria disease commences when blood-stage parasites, called merozoites, invade human erythrocytes. Whilst the process of invasion is traditionally seen as being entirely merozoite-driven, emerging data sugges...

    Authors: Marion Koch, Jaimini Cegla, Ben Jones, Yuning Lu, Ziad Mallat, Andrew M. Blagborough, Fiona Angrisano and Jake Baum

    Citation: Malaria Journal 2019 18:381

    Content type: Research

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  7. The Plasmodium falciparum parasite is the only human malaria that produces the histidine-rich protein 2 and 3 (HRP2/3) antigens. Currently, HRP2/3 are widely used in malaria rapid diagnostic tests (RDTs), but sev...

    Authors: Camelia Herman, Curtis S. Huber, Sophie Jones, Laura Steinhardt, Mateusz M. Plucinski, Jean F. Lemoine, Michelle Chang, John W. Barnwell, Venkatachalam Udhayakumar and Eric Rogier

    Citation: Malaria Journal 2019 18:380

    Content type: Research

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  8. The ongoing spread of artemisinin resistant Plasmodium falciparum malaria is a major threat to global health. In response, countries in the Greater Mekong Sub-region, including Cambodia, have declared ambitious g...

    Authors: Rebecca Thomson, Phok Sochea, Mak Sarath, Amanda MacDonald, Abigail Pratt, Steve Poyer, Henrietta Allen, Sok Kunthy, Sok Chamroeun, Kim Daro, Sourn Samean, Nou Panharith, Sok Ra, Chan Sovottha, Gary Mundy and Shunmay Yeung

    Citation: Malaria Journal 2019 18:379

    Content type: Research

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  9. Tamoxifen is an oestrogen receptor modulator that is widely used for the treatment of early stage breast cancer and reduction of recurrences. Tamoxifen is also used as a powerful research tool for controlling ...

    Authors: Ada Weinstock, Julio Gallego-Delgado, Cláudia Gomes, Julian Sherman, Cyrus Nikain, Sandra Gonzalez, Edward Fisher and Ana Rodriguez

    Citation: Malaria Journal 2019 18:378

    Content type: Research

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  10. Indian-origin rhesus (InR) are preferred for research, but strict export restrictions continue to limit their use. Chinese-origin rhesus (ChR), although easier to procure, are genetically distinct from InR and...

    Authors: Monica L. Martin, Alexis A. Bitzer, Andrew Schrader, Elke S. Bergmann-Leitner, Kim Soto, Xiaoyan Zou, Zoltan Beck, Gary R. Matyas and Sheetij Dutta

    Citation: Malaria Journal 2019 18:377

    Content type: Research

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  11. Over the last 20 years, malaria incidence has decreased across the Greater Mekong Sub-region (GMS) and the emergence of artemisinin resistance has stimulated efforts to accelerate regional elimination. In the ...

    Authors: Nou Sanann, Thomas J. Peto, Rupam Tripura, James J. Callery, Chea Nguon, Thanh Mai Bui, Stephanie D. Nofal, Lorenz von Seidlein, Dysoley Lek, Arjen M. Dondorp, Phaik Yeong Cheah and Christopher Pell

    Citation: Malaria Journal 2019 18:376

    Content type: Research

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  12. In view of recent evidence from a randomized trial in Burkina Faso that periconceptional iron supplementation substantially increases risk of spontaneous preterm birth (< 37 weeks) in first pregnancies (adjust...

    Authors: Bernard Brabin, Halidou Tinto and Stephen A. Roberts

    Citation: Malaria Journal 2019 18:374

    Content type: Research

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  13. Please be advised that one of the author names is incorrectly spelled in the published article: ‘Irene Kyomuhagi’ should be ‘Irene Kyomuhangi’.

    Authors: Tarekegn A. Abeku, Michelle E. H. Helinski, Matthew J. Kirby, Takele Kefyalew, Tessema Awano, Esey Batisso, Gezahegn Tesfaye, James Ssekitooleko, Sarala Nicholas, Laura Erdmanis, Angela Nalwoga, Chris Bass, Stephen Cose, Ashenafi Assefa, Zelalem Kebede, Tedila Habte…

    Citation: Malaria Journal 2019 18:373

    Content type: Correction

    Published on:

    The original article was published in Malaria Journal 2015 14:337

  14. Malaria in pregnancy (MiP) contributes to devastating maternal and neonatal outcomes. Coverage of intermittent preventive treatment during pregnancy (IPTp) remains alarmingly low. Data was compiled from MiP pr...

    Authors: Elaine Roman, Kristin Andrejko, Katherine Wolf, Marianne Henry, Susan Youll, Lia Florey, Erin Ferenchick and Julie R. Gutman

    Citation: Malaria Journal 2019 18:372

    Content type: Review

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  15. Malaria remains a public health issue, particularly in sub-Saharan Africa with special features of seriousness in young children and pregnant women. Adolescents and adults are reported to have acquired a semi-...

    Authors: Rella Zoleko Manego, Erik Koehne, Andrea Kreidenweiss, Brice Nzigou Mombo, Bayode Romeo Adegbite, Lia Betty Dimessa Mbadinga, Malik Akinosho, Julian Matthewman, Ayola Akim Adegnika, Michael Ramharter and Ghyslain Mombo-Ngoma

    Citation: Malaria Journal 2019 18:371

    Content type: Research

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  16. With increasing spatial heterogeneity of malaria transmission and a shift of the disease burden towards older children and adults, pregnant women attending antenatal care (ANC) have been proposed as a pragmati...

    Authors: Nina C. Brunner, Frank Chacky, Renata Mandike, Ally Mohamed, Manuela Runge, Sumaiyya G. Thawer, Amanda Ross, Penelope Vounatsou, Christian Lengeler, Fabrizio Molteni and Manuel W. Hetzel

    Citation: Malaria Journal 2019 18:370

    Content type: Research

    Published on:

  17. Please note that an author has been erroneously omitted from the author list of the published article [1].

    Authors: Adela Ida Jiram, Choo Huck Ooi, José Miguel Rubio, Shamilah Hisam, Govindarajoo Karnan, Nurnadiah Mohd Sukor, Mohd Mafe Artic, Nor Parina Ismail, Nor Wahida Alias and Ismail Aziah

    Citation: Malaria Journal 2019 18:369

    Content type: Correction

    Published on:

    The original article was published in Malaria Journal 2019 18:156

  18. Although malaria remains a noteworthy disease in South Africa, the provinces are at differing stages of the malaria elimination continuum. KwaZulu-Natal has consistently reported the lowest number of cases ove...

    Authors: Rajendra Maharaj, Ishen Seocharan, Bheki Qwabe, Moses Mkhabela, Sunitha Kissoon and Vishan Lakan

    Citation: Malaria Journal 2019 18:368

    Content type: Research

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  19. Malaria is a major public health problem in the China–Myanmar border region. The genetic structure of malaria parasite may affect its transmission model and control strategies. The present study was to analyse...

    Authors: Cang-Lin Zhang, Hong-Ning Zhou, Quan Liu and Ya-Ming Yang

    Citation: Malaria Journal 2019 18:367

    Content type: Research

    Published on:

  20. Following publication of the original article [1], the authors flagged an error in Addition file 6.

    Authors: Aayush Khadka, Nicole A. Perales, Dorothy J. Wei, Anna D. Gage, Noah Haber, Stéphane Verguet, Bryan Patenaude and Günther Fink

    Citation: Malaria Journal 2019 18:365

    Content type: Correction

    Published on:

    The original article was published in Malaria Journal 2018 17:224

  21. Long-lasting insecticidal nets (LLIN), improved diagnosis and artemisinin-based combination therapy (ACT) have reduced malaria prevalence in Papua New Guinea since 2008. Yet, national incidence trends are inco...

    Authors: Daniela Rodriguez-Rodriguez, Seri Maraga, Lina Lorry, Leanne J. Robinson, Peter M. Siba, Ivo Mueller, Justin Pulford, Amanda Ross and Manuel W. Hetzel

    Citation: Malaria Journal 2019 18:364

    Content type: Research

    Published on:

  22. Improving maternal health remains a priority to the Ghanaian government. Consequently, it has implemented the World Health Organization recommendation of distributing free long-lasting insecticidal nets (LLINs...

    Authors: Matilda Aberese-Ako, Pascal Magnussen, Gifty D. Ampofo and Harry Tagbor

    Citation: Malaria Journal 2019 18:363

    Content type: Research

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  23. Interventions to raise community awareness about malaria prevention and treatment have used various approaches with little evidence on their efficacy. This study aimed to determine the effectiveness of loudspe...

    Authors: Pyae Linn Aung, Tepanata Pumpaibool, Than Naing Soe, Jessica Burgess, Lynette J. Menezes, Myat Phone Kyaw and Liwang Cui

    Citation: Malaria Journal 2019 18:362

    Content type: Research

    Published on:

  24. Drug resistance is one of the greatest challenges of malaria control programme in Mali. Recent advances in next-generation sequencing (NGS) technologies provide new and effective ways of tracking drug-resistan...

    Authors: Seidina A. S. Diakité, Karim Traoré, Ibrahim Sanogo, Taane G. Clark, Susana Campino, Modibo Sangaré, Djeneba Dabitao, Antoine Dara, Drissa S. Konaté, Fousseyni Doucouré, Amadou Cissé, Bourama Keita, Mory Doumbouya, Merepen A. Guindo, Mahamoudou B. Toure, Nafomon Sogoba…

    Citation: Malaria Journal 2019 18:361

    Content type: Research

    Published on:

  25. Malaria remains a leading cause of morbidity and mortality in Mozambique. Increased investments in malaria control have reduced the burden, but few studies have estimated the costs of malaria in the country. T...

    Authors: Sergi Alonso, Carlos J. Chaccour, Eldo Elobolobo, Amilcar Nacima, Baltazar Candrinho, Abuchahama Saifodine, Francisco Saute, Molly Robertson and Rose Zulliger

    Citation: Malaria Journal 2019 18:360

    Content type: Research

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  26. A major health burden in Cameroon is malaria, a disease that is sensitive to climate, environment and socio-economic conditions, but whose precise relationship with these drivers is still uncertain. An improve...

    Authors: Amelie D. Mbouna, Adrian M. Tompkins, Andre Lenouo, Ernest O. Asare, Edmund I. Yamba and Clement Tchawoua

    Citation: Malaria Journal 2019 18:359

    Content type: Research

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  27. Insecticide resistance is a growing threat to malaria vector control. Ivermectin, either administered to humans or animals, may represent an alternate strategy to reduce resistant mosquito populations. The aim...

    Authors: Wondemeneh Mekuriaw, Meshesha Balkew, Louisa A. Messenger, Delenasaw Yewhalaw, Adugna Woyessa and Fekadu Massebo

    Citation: Malaria Journal 2019 18:357

    Content type: Research

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  28. Control and elimination of malaria can be accelerated by transmission-blocking interventions such as vaccines. A surface antigen of Plasmodium falciparum gametocytes, Pfs230, is a leading vaccine target antigen, ...

    Authors: Shwu-Maan Lee, Yimin Wu, John M. Hickey, Kazutoyo Miura, Neal Whitaker, Sangeeta B. Joshi, David B. Volkin, C. Richter King and Jordan Plieskatt

    Citation: Malaria Journal 2019 18:356

    Content type: Research

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  29. Malaria rapid diagnostic tests based on histidine-rich protein-2 have played a vital role in improving malaria case management and surveillance particularly in Africa, where Plasmodium falciparum is predominant. ...

    Authors: Bosco B. Agaba, Adoke Yeka, Sam Nsobya, Emmanuel Arinaitwe, Joaniter Nankabirwa, Jimmy Opigo, Paul Mbaka, Chae Seung Lim, Joan N. Kalyango, Charles Karamagi and Moses R. Kamya

    Citation: Malaria Journal 2019 18:355

    Content type: Research

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  30. CareStart™ malaria HRP2/pLDH (Pf/pan) combo test is one of the several rapid diagnostic tests (RDT) approved for diagnosis of malaria at the point of care in Tanzania. However, there are limited studies on the...

    Authors: George M. Bwire, Billy Ngasala, Manase Kilonzi, Wigilya P. Mikomangwa, Fatuma F. Felician and Appolinary A. R. Kamuhabwa

    Citation: Malaria Journal 2019 18:354

    Content type: Research

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  31. Plasmodium falciparum drug resistance surveillance is key to successful disease control and eradication. Contemporary methods that only allow determination of prevalence of resistance are expensive, time consumin...

    Authors: Rebecca Smith-Aguasca, Himanshu Gupta, Estefania Uberegui, Mara Maquina, Francisco Saute, Krijn P. Paaijmans, Alfredo Mayor and Silvie Huijben

    Citation: Malaria Journal 2019 18:351

    Content type: Methodology

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  32. Malaria elimination requires diagnostic methods able to detect parasite levels well below what is currently possible with microscopy and rapid diagnostic tests. This is particularly true in surveillance of mal...

    Authors: Abu Naser Mohon, Sisay Getie, Nusrat Jahan, Mohammad Shafiul Alam and Dylan R. Pillai

    Citation: Malaria Journal 2019 18:350

    Content type: Research

    Published on:

  33. The resistance of Plasmodium falciparum to artemisinin has been identified in Asia and some parts of Africa. The drug resistance of P. falciparum will be an obstacle to the successful elimination of malaria by 20...

    Authors: Jun Li, Yunliang Shi, Weiwei Zhang, Hui Yan, Kangming Lin, Shujiao Wei, Haiyan Wei, Yichao Yang, Shanping Huang, Yuxin Lu, Anxiang Ma and Jian Qin

    Citation: Malaria Journal 2019 18:349

    Content type: Research

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  34. Widespread elimination of malaria requires an ultra-sensitive detection method that can detect low parasitaemia levels seen in asymptomatic carriers who act as reservoirs for further transmission of the diseas...

    Authors: Philip Heraud, Patutong Chatchawal, Molin Wongwattanakul, Patcharaporn Tippayawat, Christian Doerig, Patcharee Jearanaikoon, David Perez-Guaita and Bayden R. Wood

    Citation: Malaria Journal 2019 18:348

    Content type: Research

    Published on:

  35. Gene drive mosquitoes have been proposed as a possible means to reduce the transmission of malaria in Africa. Because this technology has no prior use-history at this time, environmental risk assessments for g...

    Authors: John L. Teem, Aggrey Ambali, Barbara Glover, Jeremy Ouedraogo, Diran Makinde and Andrew Roberts

    Citation: Malaria Journal 2019 18:347

    Content type: Research

    Published on:

  36. Malaria is one of the deadliest infectious diseases caused by protozoan parasite of Plasmodium spp. Increasing resistance to anti-malarials has become global threat in control of the disease and demands for novel...

    Authors: Sonal Gupta, Juveria Khan, Priti Kumari, Chintam Narayana, R. Ayana, Malabika Chakrabarti, Ram Sagar and Shailja Singh

    Citation: Malaria Journal 2019 18:346

    Content type: Research

    Published on:

    The Correction to this article has been published in Malaria Journal 2020 19:122

  37. Malaria is a public health problem in the Brazilian Amazon region. In integrated vector management for malaria (anopheline) control, indoor residual spraying (IRS) represents one of the main tools in the basic...

    Authors: Ana Paula S. A. Corrêa, Allan K. R. Galardo, Luana A. Lima, Daniel C. P. Câmara, Josiane N. Müller, Jéssica Fernanda S. Barroso, Oscar M. M. Lapouble, Cynara M. Rodovalho, Kaio Augusto N. Ribeiro and José Bento P. Lima

    Citation: Malaria Journal 2019 18:345

    Content type: Research

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  38. Historically neglected, due to its biological peculiarities, the absence of a continuous long-term in vitro blood stage culture system and a propensity towards high morbidity rather than mortality, Plasmodium viv...

    Authors: Richard Thomson-Luque, John H. Adams, Clemens H. M. Kocken and Erica M. Pasini

    Citation: Malaria Journal 2019 18:344

    Content type: Review

    Published on:

  39. A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This study evaluated the current prevalence of Pfcrt and Pfmdr1 alleles in Plasmodium ...

    Authors: Moses N. Ikegbunam, Charles N. Nkonganyi, Bolaji N. Thomas, Charles O. Esimone, Thirumalaisamy P. Velavan and Olusola Ojurongbe

    Citation: Malaria Journal 2019 18:343

    Content type: Research

    Published on:

  40. Chloroquine (CQ) was the drug of choice for decades in the treatment of falciparum malaria until resistance emerged. CQ is suggested to accumulate in the parasite’s digestive vacuole (DV), where it unfolds its...

    Authors: Sarah J. Reiling and Petra Rohrbach

    Citation: Malaria Journal 2019 18:342

    Content type: Research

    Published on:

  41. Epidemiological surveys of malaria currently rely on microscopy, polymerase chain reaction assays (PCR) or rapid diagnostic test kits for Plasmodium infections (RDTs). This study investigated whether mid-infrared...

    Authors: Emmanuel P. Mwanga, Elihaika G. Minja, Emmanuel Mrimi, Mario González Jiménez, Johnson K. Swai, Said Abbasi, Halfan S. Ngowo, Doreen J. Siria, Salum Mapua, Caleb Stica, Marta F. Maia, Ally Olotu, Maggy T. Sikulu-Lord, Francesco Baldini, Heather M. Ferguson, Klaas Wynne…

    Citation: Malaria Journal 2019 18:341

    Content type: Research

    Published on:

  42. G6PD enzyme deficiency is a common enzymatic X-linked disorder. Deficiency of the G6PD enzyme can cause free radical-mediated oxidative damage to red blood cells, leading to premature haemolysis. Treatment of Pla...

    Authors: Eugenia Lo, Daibin Zhong, Beka Raya, Kareen Pestana, Cristian Koepfli, Ming-Chieh Lee, Delenasaw Yewhalaw and Guiyun Yan

    Citation: Malaria Journal 2019 18:340

    Content type: Research

    Published on:

  43. The recent emergence in Southeast Asia of artemisinin resistance poses major threats to malaria control and elimination globally. Green nanotechnologies can constitute interesting tools for discovering anti-ma...

    Authors: Loick P. Kojom Foko, Francois Eya’ane Meva, Carole E. Eboumbou Moukoko, Agnes A. Ntoumba, Marie I. Ngaha Njila, Philippe Belle Ebanda Kedi, Lawrence Ayong and Leopold G. Lehman

    Citation: Malaria Journal 2019 18:337

    Content type: Research

    Published on:

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