Skip to main content

Table 2 Sensitivity, specificity & ROC* for saliva derived seroprevalence to P. falciparum merozoite surface antigens

From: Human saliva as a source of anti-malarial antibodies to examine population exposure to Plasmodium falciparum

 

Sensitivity (95% CI)

Specificity (95% CI)

ROC (95% CI)

AMA-1

   

Tanzania Oracol

76.7 (54.9-90.6)

100 (87.7-100)

0.88 (0.8-0.96)

Tanzania Orasure

64 (42.5-82)

92.9 (76.5-99.1)

0.78 (0.68-0.89)

The Gambia

68 (56-78.8)

91.2(85-95.6)

0.80(0.74-0.86)

MSP-1 19

   

Oracol

46.7 (21.3-73.4)

97.4 (86.2-99.9)

0.72 (0.58-0.85)

Orasure

66.7 (38.4-88.2)

90.0(75.2-97.1)

0.78 (0.64-0.91)

The Gambia

53 (40.1-66.5)

94.2(89-87.5)

0.74(0.67-0.81)

  1. * ROC = receiver operating characteristic curve; the average of sensitivity and specificity
  2. Fingerprick derived plasma antibody prevalence was the gold standard for sensitivity and specificity analysis.
Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us