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  1. Malaria remains a public health problem in regions of Northeastern India because of favourable bio-geographic transmission conditions, poor access to routine healthcare, and inadequate infrastructure for publi...

    Authors: Carinthia B. Nengnong, Mattimi Passah, Mark L. Wilson, Elisa Bellotti, Anne Kessler, Bibha R. Marak, Jane M. Carlton, Rajiv Sarkar and Sandra Albert
    Citation: Malaria Journal 2024 23:83
  2. Adults infected with Plasmodium spp. in endemic areas need to be re-evaluated in light of global malaria elimination goals. They potentially undermine malaria interventions but remain an overlooked aspect of publ...

    Authors: Nadine Kalenda Kayiba, Yuko Nitahara, Evariste Tshibangu-Kabamba, Denis Kalambayi Mbuyi, Augustin Kabongo-Tshibaka, Nestor Tshituka Kalala, Barthélemy Mukenga Tshiebue, Katherine-Sofia Candray-Medina, Natsuko Kaku, Yu Nakagama, Niko Speybroeck, Dieudonné Ngoyi Mumba, Ghislain Tumba Disashi, Akira Kaneko and Yasutoshi Kido
    Citation: Malaria Journal 2024 23:82
  3. Vector surveillance is among the World Health Organization global vector control response (2017–2030) pillars. Human landing catches are a gold standard but difficult to implement and potentially expose collec...

    Authors: Jackline Kosgei, John E. Gimnig, Vincent Moshi, Seline Omondi, Daniel P. McDermott, Martin J. Donnelly, Collins Ouma, Bernard Abong’o and Eric Ochomo
    Citation: Malaria Journal 2024 23:81
  4. Malaria vector control activities in Sudan rely largely on Long-Lasting Insecticidal Nets (LLINs), Indoor Residual Spray (IRS) and Larval Source Management (LSM). The present study attempted to determine cost ...

    Authors: Sami M. HasapAla, Rasha S. Azrag and Osama M. Awad
    Citation: Malaria Journal 2024 23:80
  5. Tanzania is currently implementing therapeutic efficacy studies (TES) in areas of varying malaria transmission intensities as per the World Health Organization (WHO) recommendations. In TES, distinguishing rei...

    Authors: Deus S. Ishengoma, Celine I. Mandara, Rashid A. Madebe, Marian Warsame, Billy Ngasala, Abdunoor M. Kabanywanyi, Muhidin K. Mahende, Erasmus Kamugisha, Reginald A. Kavishe, Florida Muro, Renata Mandike, Sigsbert Mkude, Frank Chacky, Ritha Njau, Troy Martin, Ally Mohamed…
    Citation: Malaria Journal 2024 23:79
  6. Vegetation health (VH) is a powerful characteristic for forecasting malaria incidence in regions where the disease is prevalent. This study aims to determine how vegetation health affects the prevalence of mal...

    Authors: Gouvidé Jean Gbaguidi, Mouhamed Idrissou, Nikita Topanou, Walter Leal Filho and Guillaume K. Ketoh
    Citation: Malaria Journal 2024 23:78
  7. Pyrethroid-based indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs) have been employed as key vector control measures against malaria in Namibia. However, pyrethroid resistance in Anopheles

    Authors: Rosalia N. Joseph, Tabeth Mwema, Seth J. Eiseb, Deodatus V. Maliti, Munyaradzi Tambo, Iitula Iitula, Lydia Eloff, Ophilia Lukubwe, Cara Smith-Gueye, Élodie A. Vajda, Allison Tatarsky, Stark T. Katokele, Petrina N. Uusiku, Dennis Walusimbi, Sheila B. Ogoma, Davis R. Mumbengegwi…
    Citation: Malaria Journal 2024 23:77
  8. Malaria remains a significant cause of morbidity and mortality in Ethiopia with an estimated 3.8 million cases in 2021 and 61% of the population living in areas at risk of malaria transmission. Throughout the ...

    Authors: Lauren Bradley, Delenasaw Yewhalaw, Elizabeth Hemming-Schroeder, Brook Jeang, Ming-Chieh Lee, Endalew Zemene, Teshome Degefa, Eugenia Lo, Christopher King, James Kazura and Guiyun Yan
    Citation: Malaria Journal 2024 23:76
  9. The Great Mekong Subregion has attained a major decline in malaria cases and fatalities over the last years, but residual transmission hotspots remain, supposedly fueled by forest workers and migrant populatio...

    Authors: Anaïs Pepey, Marc Souris, Saorin Kim, Thomas Obadia, Sophy Chy, Malen Ea, Sivkeng Ouk, Franck Remoue, Siv Sovannaroth, Ivo Mueller, Benoit Witkowski and Amélie Vantaux
    Citation: Malaria Journal 2024 23:75
  10. Understanding of malaria ecology is a prerequisite for designing locally adapted control strategies in resource-limited settings. The aim of this study was to utilize the spatial heterogeneity in malaria trans...

    Authors: Guofa Zhou, John Githure, Ming-Chieh Lee, Daibin Zhong, Xiaoming Wang, Harrysone Atieli, Andrew K. Githeko, James Kazura and Guiyun Yan
    Citation: Malaria Journal 2024 23:74
  11. Delays in malaria treatment can not only lead to severe and even life-threatening complications, but also foster transmission, putting more people at risk of infection. This study aimed to investigate the fact...

    Authors: Lianyu Jia, Xiaoyu Chen, Zhanchun Feng, Shangfeng Tang and Da Feng
    Citation: Malaria Journal 2024 23:73
  12. Recently, bacterial endosymbiont, including Wolbachia and Microsporidia were found to limit the infection of Anopheles mosquitoes with Plasmodium falciparum. This study aimed to investigate the natural presence o...

    Authors: Minassou Juvénal Ahouandjinou, Arthur Sovi, Aboubakar Sidick, Wilfried Sewadé, Come Zinsou Koukpo, Saïd Chitou, Linda Towakinou, Bruno Adjottin, Steve Hougbe, Filémon Tokponnon, Germain Gil Padonou, Martin Akogbéto, Louisa A. Messenger and Razaki A. Ossè
    Citation: Malaria Journal 2024 23:72
  13. Therapeutic efficacy studies (TESs) and detection of molecular markers of drug resistance are recommended by the World Health Organization (WHO) to monitor the efficacy of artemisinin-based combination therapy...

    Authors: Catherine Bakari, Celine I. Mandara, Rashid A. Madebe, Misago D. Seth, Billy Ngasala, Erasmus Kamugisha, Maimuna Ahmed, Filbert Francis, Samwel Bushukatale, Mercy Chiduo, Twilumba Makene, Abdunoor M. Kabanywanyi, Muhidin K. Mahende, Reginald A. Kavishe, Florida Muro, Sigsbert Mkude…
    Citation: Malaria Journal 2024 23:71
  14. Birds chronically infected with avian malaria parasites often show relapses of parasitaemia after latent stages marked by absence of parasites in the peripheral circulation. These relapses are assumed to resul...

    Authors: Tanja Himmel, Josef Harl, Julia Matt, Nora Nedorost, Tatjana Iezhova, Mikas Ilgūnas, Gediminas Valkiūnas and Herbert Weissenböck
    Citation: Malaria Journal 2024 23:70
  15. There are several indications that pesticides used in agriculture contribute to the emergence and spread of resistance of mosquitoes to vector control insecticides. However, the impact of such an indirect sele...

    Authors: Christabelle G. Sadia, Jean-Marc Bonneville, Marius G. Zoh, Behi K. Fodjo, France-Paraudie A. Kouadio, Sebastien K. Oyou, Benjamin G. Koudou, Beatrice A. Adepo-Gourene, Stephane Reynaud, Jean-Philippe David and Chouaibou S. Mouahamadou
    Citation: Malaria Journal 2024 23:69
  16. Genetic surveillance of the Plasmodium falciparum parasite shows great promise for helping National Malaria Control Programmes (NMCPs) assess parasite transmission. Genetic metrics such as the frequency of polyge...

    Authors: Wesley Wong, Stephen F. Schaffner, Julie Thwing, Mame Cheikh Seck, Jules Gomis, Younouss Diedhiou, Ngayo Sy, Medoune Ndiop, Fatou Ba, Ibrahima Diallo, Doudou Sene, Mamadou Alpha Diallo, Yaye Die Ndiaye, Mouhamad Sy, Aita Sene, Djiby Sow…
    Citation: Malaria Journal 2024 23:68
  17. The malaria incidence data from a malaria prevention study from the Rift Valley, Central Ethiopia, were reanalysed. The objective was to investigate whether including an administrative structure within the soc...

    Authors: Taye Gari and Bernt Lindtjørn
    Citation: Malaria Journal 2024 23:67
  18. Insecticide-treated nets (ITNs) contributed significantly to the decline in malaria since 2000. Their protective efficacy depends not only on access, use, and net integrity, but also location of people within ...

    Authors: Julius I. Odero, Bernard Abong’o, Vincent Moshi, Sheila Ekodir, Steven A. Harvey, Eric Ochomo, John E. Gimnig, Nicole L. Achee, John P. Grieco, Prisca A. Oria and April Monroe
    Citation: Malaria Journal 2024 23:66
  19. Neonicotinoids are potential alternatives for controlling pyrethroid-resistant mosquitoes, but their efficacy against malaria vector populations of sub-Saharan Africa has yet to be investigated. The aim of the...

    Authors: Fred A. Ashu, Caroline Fouet, Marilene M. Ambadiang, Véronique Penlap-Beng and Colince Kamdem
    Citation: Malaria Journal 2024 23:65
  20. Malaria remains a global health challenge, disproportionately affecting vulnerable communities. Despite substantial progress, the emergence of anti-malarial drug resistance poses a constant threat. The Greater...

    Authors: Giulia Manzoni, Rady Try, Jean Olivier Guintran, Céline Christiansen-Jucht, Elodie Jacoby, Siv Sovannaroth, Zaixing Zhang, Vilasack Banouvong, Matthew Scott Shortus, Rita Reyburn, Chitsavang Chanthavisouk, Nay Yi Yi Linn, Badri Thapa, San Kyawt Khine, Prayuth Sudathip, Deyer Gopinath…
    Citation: Malaria Journal 2024 23:64
  21. Malaria elimination requires closely co-ordinated action between neighbouring countries. In Southern Africa several countries have reduced malaria to low levels, but the goal of elimination has eluded them thu...

    Authors: Chadwick H. Sikaala, Bongani Dlamini, Alphart Lungu, Phelele Fakudze, Mukosha Chisenga, Chishala Lukwesa Siame, Nyasha Mwendera, Dumisani Shaba, John M. Chimumbwa and Immo Kleinschmidt
    Citation: Malaria Journal 2024 23:62
  22. Children are particularly at risk of malaria. This analysis consolidates the clinical data for pyronaridine–artesunate (PA) paediatric granules in children from three randomized clinical trials and a real-worl...

    Authors: Michael Ramharter, Abdoulaye A. Djimde, Isabelle Borghini-Fuhrer, Robert Miller, Jangsik Shin, Adam Aspinall, Naomi Richardson, Martina Wibberg, Lawrence Fleckenstein, Sarah Arbe-Barnes and Stephan Duparc
    Citation: Malaria Journal 2024 23:61
  23. When integrated with insecticide-treated bed nets, larval control of Anopheles mosquitoes could fast-track reductions in the incidence of human malaria. However, larval control interventions may deliver suboptim...

    Authors: Faith I. Ebhodaghe, Irma Sanchez-Vargas, Clement Isaac, Brian D. Foy and Elizabeth Hemming-Schroeder
    Citation: Malaria Journal 2024 23:60
  24. By 2022, the Government of Indonesia had successfully eliminated malaria in 389 out of 514 districts but continues to face a challenge in Eastern Indonesia where 95% of the total 2021 malaria cases were report...

    Authors: Dee Jupp, Sherria Ayuandini, Frisca Tobing, Denny Halim, Enny Kenangalem, Maria E. Sumiwi, Hellen D. Prameswari, Minerva Theodora, Hermawan Susanto, Riskha T. P. Dewi, Dedy Supriyanto, Bayu Kurnia, Mrunal Shetye, Ermi Ndoen and Yuka Onishi
    Citation: Malaria Journal 2024 23:59
  25. Qualified malaria diagnosis competency has contributed to the great achievement of malaria elimination in China. After eliminating malaria, it is still critical to the prevention of re-establishment of malaria...

    Authors: He Yan, Mei Li, Zhi-gui Xia and Jian-hai Yin
    Citation: Malaria Journal 2024 23:58
  26. Gabon still bears significant malaria burden despite numerous efforts. To reduce this burden, policy-makers need strategies to design effective interventions. Besides, malaria distribution is well known to be ...

    Authors: Fabrice Mougeni, Bertrand Lell, Ngianga-Bakwin Kandala and Tobias Chirwa
    Citation: Malaria Journal 2024 23:57
  27. Cambodia aims to eliminate all forms of malaria by 2025. In 2020, 90% of all malaria cases were Plasmodium vivax. Thus, preventing P. vivax and relapse malaria is a top priority for elimination. 14-day primaquine...

    Authors: Dysoley Lek, Yu-Cheng Tsai, Jillian Hirano, Siv Sovannaroth, Voeurng Bunreth, Prak Vonn, Or Vannthen, Tol Bunkea, Top Samphornarann, Nguon Sokomar, Mak Sarath, Soy Ty Kheang, Evelyn Wong, Michelle K. Burbach, Jayme Hughes and Huy Rekol
    Citation: Malaria Journal 2024 23:56
  28. Plasmodium vivax Duffy binding protein (PvDBP) is a merozoite surface protein located in the micronemes of P. vivax. The invasion of human reticulocytes by P. vivax merozoites depends on the parasite DBP binding ...

    Authors: Abnet Abebe, Cheikh Cambel Dieng, Sisay Dugassa, Deriba Abera, Tassew T. Shenkutie, Ashenafi Assefa, Didier Menard, Eugenia Lo and Lemu Golassa
    Citation: Malaria Journal 2024 23:55
  29. Mass Drug Administration (MDA) has become a mainstay for the control of several diseases over the last two decades. Successful implementation of MDA programmes requires community participation and can be threa...

    Authors: Christian Kositz, Hristina Vasileva, Nuredin Mohammed, Jane Achan, Edgard Diniba Dabira, Umberto D’Alessandro, John Bradley and Michael Marks
    Citation: Malaria Journal 2024 23:54
  30. The infection of the liver by Plasmodium parasites is an obligatory step leading to malaria disease. Following hepatocyte invasion, parasites differentiate into replicative liver stage schizonts and, in the case ...

    Authors: Gabriel Mitchell, Laura Torres, Matthew E. Fishbaugher, Melanie Lam, Vorada Chuenchob, Reena Zalpuri, Shreya Ramasubban, Caitlin N. Baxter, Erika L. Flannery, Anke Harupa, Sebastian A. Mikolajczak and Danielle M. Jorgens
    Citation: Malaria Journal 2024 23:53
  31. Against a backdrop of stalled progress in malaria control, it is surprising that the various forms of malaria chemoprevention are not more widely used. The World Health Organization (WHO) has recommended sever...

    Authors: Jasper Littmann, Dorothy Achu, Miriam K. Laufer, Corine Karema and David Schellenberg
    Citation: Malaria Journal 2024 23:51
  32. Despite the progress made in this decade towards malaria elimination, it remains a significant public health concern in India and many other countries in South Asia and Asia Pacific region. Understanding the h...

    Authors: Mrigendra P. Singh, Harsh Rajvanshi, Praveen K. Bharti, Anup R. Anvikar and Altaf A. Lal
    Citation: Malaria Journal 2024 23:50
  33. Over the last decades, the number of malaria cases has drastically reduced in Cambodia. As the overall prevalence of malaria in Cambodia declines, residual malaria transmission becomes increasingly fragmented ...

    Authors: Mathilde Grimée, Costanza Tacoli, Mirco Sandfort, Thomas Obadia, Aimee R. Taylor, Amélie Vantaux, Leanne J. Robinson, Dysoley Lek, Rhea J. Longley, Ivo Mueller, Jean Popovici, Michael T. White and Benoît Witkowski
    Citation: Malaria Journal 2024 23:49
  34. Immunogenic cell death (ICD) is a type of regulated cell death that plays a crucial role in activating the immune system in response to various stressors, including cancer cells and pathogens. However, the inv...

    Authors: Yan-hui Zhang, Li-hua Xie, Jian Li, Yan-wei Qi and Jia-jian Shi
    Citation: Malaria Journal 2024 23:48
  35. South Africa set a target to eliminate malaria by 2023, with KwaZulu-Natal (KZN) Province the malaria-endemic province closest to achieving this goal. Objective two of the National Malaria Elimination Strategi...

    Authors: Maxwell Mabona, Thembekile Zwane, Jaishree Raman, Lazarus Kuonza, Babongile Mhlongo and Poncho Phafane
    Citation: Malaria Journal 2024 23:47
  36. The aim of this study is to design ad hoc malaria learning (ML) approaches to predict clinical outcome in all patients with imported malaria and, therefore, to identify the best clinical setting.

    Authors: Alessandra D’Abramo, Francesco Rinaldi, Serena Vita, Riccardo Mazzieri, Angela Corpolongo, Claudia Palazzolo, Tommaso Ascoli Bartoli, Francesca Faraglia, Maria Letizia Giancola, Enrico Girardi and Emanuele Nicastri
    Citation: Malaria Journal 2024 23:46
  37. The male mosquito microbiome may be important for identifying ideal candidates for disease control. Among other criteria, mosquito-associated symbionts that have high localization in both male and female mosqu...

    Authors: Richardson K. Egyirifa and Jewelna Akorli
    Citation: Malaria Journal 2024 23:45
  38. Over the past thirty years, epigenetic regulation of gene expression has gained increasing interest as it was shown to be implicated in illnesses ranging from cancers to parasitic diseases. In the malaria para...

    Authors: Thibaud Reyser, Lucie Paloque, Jean-Michel Augereau, Luisa Di Stefano and Françoise Benoit-Vical
    Citation: Malaria Journal 2024 23:44
  39. Malaria remains an enduring public health concern in Indonesia, exacerbated by its equatorial climate that fosters the proliferation of Anopheles mosquitoes. This study seeks to assess the performance of the mala...

    Authors: Hamzah Hasyim, Heni Marini, Misnaniarti Misnaniarti, Rostika Flora, Iche Andriyani Liberty, Ahmed Elagali, Hartoni Hartoni and Fadhilah Eka Maharani
    Citation: Malaria Journal 2024 23:43
  40. Malaria is one of the most important vector-borne diseases of humans with an estimated 241 million cases worldwide in 2020. As an urban and periurban mosquito species, Anopheles stephensi is exposed to artificial...

    Authors: Jose Luis Llergo, Helena Garuti, Celia Lopez, Julia Sanchez and David Calvo
    Citation: Malaria Journal 2024 23:42
  41. An estimated 50% of suspected malaria cases in sub-Saharan Africa first seek care in the private sector, especially in private medicine retail outlets. Quality of care in these outlets is generally unknown but...

    Authors: Meley Woldeghebriel, Ezinne Aso, Erica Berlin, Chizoba Fashanu, Sylvia N. Kirumira, Felix Lam, Robert Mugerwa, Juliet Nakiganda, Tayo Olaleye, Jimmy Opigo, Funlola Osinupebi, Natalie Priestley, Rodger Stringham, Perpetua Uhomoibhi, Theodoor Visser, Abigail Ward…
    Citation: Malaria Journal 2024 23:41
  42. Artemisinin-based combination therapy (ACT) has been effective in the supervised treatment of uncomplicated malaria in Ghana. Since ACT usage is primarily unsupervised, this study aimed to determine the effect...

    Authors: Mawusi Adepa Mawuli, Linda Eva Amoah, Liwang Cui, Neils Ben Quashie and Yaw Asare Afrane
    Citation: Malaria Journal 2024 23:40
  43. Seasonal Malaria Chemoprevention (SMC) is a highly effective intervention for preventing malaria, particularly in areas with highly seasonal transmission. Monitoring and evaluating (M&E) SMC programmes are com...

    Authors: Monica Anna de Cola, Elisabeth G. Chestnutt, Sol Richardson, Matthieu Baudry, Chuks Nnaji, Taiwo Ibinaiye, Azoukalné Moukénet, Kunle Rotimi, Benoît Sawadogo, Joshua Okafor, Cheick Saïd Compaoré, Chibuzo Oguoma, Christian Rassi and Arantxa Roca-Feltrer
    Citation: Malaria Journal 2024 23:39
  44. It was hypothesized that glucose-6-phosphate dehydrogenase (G6PD) deficiency confers a protective effect against malaria infection, however, safety concerns have been raised regarding haemolytic toxicity cause...

    Authors: Usa Boonyuen, Beatriz Aira C. Jacob, Jutamas Wongwigkan, Kamonwan Chamchoy, Natsamon Singha-art, Natnicha Pengsuk, Duantida Songdej, Emily R. Adams, Thomas Edwards, Supat Chamnanchanunt, Syazwani Itri Amran, Nurriza Ab Latif, Naveen Eugene Louis and Shamini Chandran
    Citation: Malaria Journal 2024 23:38
  45. A major challenge to malaria elimination is identifying and targeting populations that are harbouring residual infections and contributing to persistent transmission. In many near-elimination settings in South...

    Authors: Sarah Gallalee, Iska Zarlinda, Martha G. Silaen, Chris Cotter, Carmen Cueto, Iqbal R. F. Elyazar, Jerry O. Jacobson, Roly Gosling, Michelle S. Hsiang, Adam Bennett, Farah N. Coutrier and Jennifer L. Smith
    Citation: Malaria Journal 2024 23:37
  46. Timely molecular surveillance of Plasmodium falciparum kelch 13 (k13) gene mutations is essential for monitoring the emergence and stemming the spread of artemisinin resistance. Widespread artemisinin resistance,...

    Authors: Brook Jeang, Daibin Zhong, Ming-Chieh Lee, Harrysone Atieli, Delenasaw Yewhalaw and Guiyun Yan
    Citation: Malaria Journal 2024 23:36
  47. Sri Lanka after eliminating malaria in 2012, is in the prevention of re-establishment (POR) phase. Being a tropical country with high malariogenic potential, maintaining vigilance is important. All malaria cas...

    Authors: Kumudunayana T. Gunasekera, Risintha G. Premaratne, Shiroma M. Handunnetti, Jagathpriya Weerasena, Sunil Premawansa and Deepika S. Fernando
    Citation: Malaria Journal 2024 23:35

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