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Table 1 Demographic, parasitological and hematological characteristics of the study population

From: Suppression of circulating IgD+CD27+ memory B cells in infants living in a malaria-endemic region of Kenya

 

Kisumu

 

Nandi

 

Parameter

12 months

18 months

24 months

p- value

12 months

18 months

24 months

p -value

No. of participants

24

24

24

 

21

21

21

 

Gender

        

   Male (n[%])

14(58)

14 (58)

14 (58)

 

9 (43)

9 (43)

9 (43)

 

P. falciparum BS+

0

0

0

 

0

0

0

 

P.falciparum Q-PCR+ (n[%])*

13 (54)

5 (21)

8 (33)

<0.0001 a

8 (38)

5 (24)

3 (14)

<0.0001 a

Temperature °C

36.55(0.008)

36.51(0.48)

36.27(0.12)

 

36.64((0.34)

36.58(0.4)

36.74(0.1)

 

Erythrocyte indices

        

   Hb conc (g/dl)

10.85(0.25)

11.07(0.26)

11.50(0.26)

0.0390 b

11.21(0.26)

11.37(0.28)

11.76(0.34)

0.0524b

   RBCs (106/µl)

5.00(0.07)

4.90(0.14)

4.68(0.09)

0.0191 b

4.73(0.01)

5.03 (0.08)

4.77(0.01)

0.0019 b

  1. Data presented as Mean (SEM) unless otherwise stated
  2. Abbreviations: Hb conc hemoglobin concentration; RBCs red blood cells. Statistically significant p ≤0.05 are in bold
  3. aThe differences in proportions over the three time points was determined using Fischer exact test
  4. bAnalysis of the continuous variables over the three time points was determined by Friedman test with post-hoc Dunns test for multiple comparisons
  5. *Parasitemic infants were significantly higher in Kisumu relative to Nandi at 12 (p = 0.0331), 18 (p = 0.7351) and 24 months (p = 0.0025)