Table 2 Factors associated with the presence of the resa2 T1526C allele in P. falciparum infected Beninese patients. Analysis without mixed isolates
From: Possible association of the Plasmodium falciparum T1526C resa2 gene mutation with severe malaria
T1526C SNP | Wild allele | p value | |
|---|---|---|---|
Infected patients n (%) | 10 (10,5) | 85 (89,5) | |
Variables | |||
Sex | |||
Male | 8 (80) | 53 (62) | 0.3 |
Female | 2 (20) | 32 (38) | |
Age (months) | |||
Median (min-max) | 35 (24–108) | 48 (4–114) | 0.5 |
In quartile | |||
<=24 months | 4 (40) | 24 (28) | |
24.1-48 | 2 (20) | 22 (26) | 0.6 |
48.1-84 | 3 (30) | 17 (20) | |
>84 | 1 (10) | 22 (26) | |
Malaria | |||
Severe | 8 (80) | 43 (51) | 0.08 |
Uncomplicated | 2 (20) | 42 (49) | |
Parasitaemia (%) | |||
Median (min-max) | 7 (0.2-36) | 3 (0.01-65) | 0.2 |
By category | |||
>4% | 7 (70) | 32 (38) | 0.05 |
<=4% | 3 (30) | 53 (62) | |
Malaria prophylaxis | |||
Yes | 3 (38) | 30 (41) | 0.8 |
No | 5 (62) | 44 (59) | |
Splenomegalia | |||
Yes | 2 (20) | 27 (32) | 0.4 |
No | 8 (80) | 58 (78) |