Vaccination | Ad5 naive | Ad5 immune |
---|
Naive | 2.71 | 2.71 |
Ad5‒CSP/Ad5‒CSP | 791.25 | 2.80 |
Ad5‒CSP/Ad4‒CSP | 708.00 | 74.50 |
Ad4‒CSP/Ad4‒CSP | 527.20 | 79.60 |
Ad4‒CSP/Ad5‒CSP | 1100 | 57.60 |
- All vaccinations, inclusive of homologous Ad4-CSP prime boost, elicited fewer IFNγ secreting splenocytes in Ad5 immune animals as measured by ELISpot. The table displays the mean numbers of spot forming cells per 500,000 splenocytes from spleens of Ad5 naïve and Ad5 immune mice treated with each prime boost regimen.