Figure 1

CYP, MAO-A & B activity plotted as % parent loss for PQ after two-hour incubation. Concentrations were as follows: PQ was at 10 mM, CYPs, MAOs were at 100 mg/ml, NADP was 1.3 mM, MgCl₂ and G6P were both 3.3 mM, and G6PD was 1 Unit/ml. 3A4, 2D6, 2 C19, and MAO-A show activity. Each experiment was done with an n of four to eight. Error reported as SD.