Skip to main content

Table 1 lists the immunohistochemical results for cleaved Caspase 3 and the hearing ability of the animals

From: Apoptosis of the fibrocytes type 1 in the spiral ligament and blood labyrinth barrier disturbance cause hearing impairment in murine cerebral malaria

Animal number

Malaria manifestation

ED[7]

Hearing loss

Cleaved Caspase 3

    

IHC

OHC

SGC

SV

SL

Li

CM1

cerebral

6

No

-

-

-

-

+

-

CM2

cerebral

7

Yes

-

-

+

-

++

-

CM3

cerebral

5

Yes

-

-

+

-

+

+

CM4

cerebral

6

Yes

-

-

+

-

++

+

CM5

cerebral

5

Yes

-

-

+

-

++

+

CM6

cerebral

7

No

-

-

-

-

+

-

CM7

cerebral

7

No

-

-

-

-

+

-

CO1

not infected

11

No

-

-

-

-

-

-

CO2

not infected

11

No

-

-

-

-

-

-

CO3

not infected

11

No

-

-

-

-

-

-

  1. The evaluation of the slices was done in a semi-quantitative manner: ++ strong reaction, + mild reaction,-no reaction. IHC: inner hair cells, OHC: outer hair cells, SGC: spiral ganglion cells, SV: stria vascularis, SL: spiral ligament, Li: limbus, ED: euthanisia day after infection
Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us